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Denervation and High-Fat Diet Reduce Insulin Signaling in T-Tubules in Skeletal Muscle of Living Mice
Online-Only Appendix
Files in this Data Supplement:
Supplementary Figure 1 Muscle denervation and high-fat feeding reduce maximal insulin-mediated 2-deoxy-glucose (2DG) uptake in incubated mouse EDL muscle.
Supplementary Figure and Movie Legends
Movie 1: Insulin activated PIP3 production progressing from the sarcolemma into the t-tubules in control muscle
Movie 2: Insulin activated PIP3 production progressing from the sarcolemma into the t-tubules in denervated muscle
Movie 3: Insulin activated PIP3 production progressing from the sarcolemma into the t-tubules in muscle of a high-fat fed mouse
This Article
Published online before print
October 3, 2007
, doi:
10.2337/db07-0516
Diabetes
January 2008
vol. 57
no. 1
13-23
Abstract
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