Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

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FIG. 5.
FIG. 5.

Antibiotic treatment prevented high-fat diet–induced adipocyte hypertrophy. A: Adipocyte size distribution (%). B: Adipocyte mean area (μm2). C: Cell density (arbitrary unit). D: Representative adipose tissue staining in mice fed normal diet (CT), normal diet and antibiotics (CT-Ab), high-fat diet (HF), or high-fat diet and antibiotics (HF-Ab) for 4 weeks. Data are means ± SE. Data with different superscript letters are significantly different (P < 0.05) according to the post hoc ANOVA statistical analysis.

This Article

  1. Diabetes vol. 57 no. 6 1470-1481