Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

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FIG. 8.
FIG. 8.

Hypothesis for bacteria-induced metabolic disease. On excessive high-fat feeding, intestinal microflora changes. This is associated with an increased intestinal permeability. Consequently, endotoxemia increases and triggers inflammation and metabolic disorders.

This Article

  1. Diabetes vol. 57 no. 6 1470-1481