Dapagliflozin, a Selective SGLT2 Inhibitor, Improves Glucose Homeostasis in Normal and Diabetic Rats

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FIG. 3.
FIG. 3.

Single oral doses of dapagliflozin stimulate an increase in urinary glucose excretion (left) and increased urine volume (right) in ZDF rats over 6 h post-dose (A) and 24 h post-dose (B). □, Vehicle treatment; ▪, dapagliflozin treatment. *P < 0.0001, †P < 0.05, each vs. vehicle. BW, body weight.

This Article

  1. Diabetes vol. 57 no. 6 1723-1729