Dapagliflozin lowers plasma glucose levels in ZDF rats after single oral doses. Rats were in the fed state at the initiation
of the experiment. Access to food was restricted over the first 6 h post-dose, but access to food was restored for the remaining
18 h post-dose.
, Vehicle; ▪, 0.01 mg/kg; , 0.1 mg/kg; □, 1 mg/kg. *P < 0.0001, †P < 0.05, each vs. vehicle.