Effect of high glucose conditions on glyoxalase-1 activity. Quantification of glyoxalase-1 activity in whole-body extracts
of 5-day-old wild-type (WT) animals, cultured under standard and high glucose conditions, or sorbitol as control. Results
are the means ± SE of three independent experiments; value from a t test (***P < 0.001) comparing wild type under standard conditions vs. wild type under high glucose conditions.