Enhancement of Muscle Mitochondrial Oxidative Capacity and Alterations in Insulin Action Are Lipid Species Dependent

TABLE 2

Body mass, fat pad mass, and tissue triglyceride levels in mice

Low-fat diet MCFAs LCFAs
Body mass (g) 28.2 ± 0.5 28.7 ± 0.6 29.1 ± 1.0
Fat mass (%) 14.7 ± 0.6 17.3 ± 1.7 25.6 ± 1.9*
Muscle triglycerides (μmol/g) 11.1 ± 0.8 13.0 ± 2.8 19.7 ± 1.9*
Liver triglycerides (μmol/g) 8.5 ± 0.7 49.7 ± 4.4* 20.1 ± 2.7*
  • Data are means ± SE for n = 6–11 animals. Fat mass (%) was determined by dual-energy X-ray absorptiometry scanning.

  • *P < 0.01 vs. low fat;

  • P < 0.01 vs. MCFA;

  • P < 0.05 vs. MCFA.

This Article

  1. Diabetes vol. 58 no. 11 2547-2554