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Table of Contents

February 2009; 58 (2)

Commentaries

    • Guy A. Rutter

    Regulating Glucagon Secretion: Somatostatin in the Spotlight

    Diabetes February 2009 58:299-301; doi:10.2337/db08-1534
    • Robert S. Lindsay

    Many HAPO Returns: Maternal Glycemia and Neonatal Adiposity: New Insights from the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) Study

    Diabetes February 2009 58:302-303; doi:10.2337/db08-1562
    • David A. Jacobson,
    • Barton L. Wicksteed,
    • and Louis H. Philipson

    The α-Cell Conundrum: ATP-Sensitive K+ Channels and Glucose Sensing

    Diabetes February 2009 58:304-306; doi:10.2337/db08-1618
    • William T. Cefalu

    Inflammation, Insulin Resistance, and Type 2 Diabetes: Back to the Future?

    Diabetes February 2009 58:307-308; doi:10.2337/db08-1656

New Methodologies and Databases

    • Zihao Wang,
    • Kyoungsook Park,
    • Frank Comer,
    • Linda C. Hsieh-Wilson,
    • Christopher D. Saudek,
    • and Gerald W. Hart

    Site-Specific GlcNAcylation of Human Erythrocyte Proteins: Potential Biomarker(s) for Diabetes

    Diabetes February 2009 58:309-317; published ahead of print November 4, 2008, doi:10.2337/db08-0994

Metabolism

    • Bronwen Martin,
    • Erin Golden,
    • Olga D. Carlson,
    • Paul Pistell,
    • Jie Zhou,
    • Wook Kim,
    • Brittany P. Frank,
    • Sam Thomas,
    • Wayne A. Chadwick,
    • Nigel H. Greig,
    • Gillian P. Bates,
    • Kirupa Sathasivam,
    • Michel Bernier,
    • Stuart Maudsley,
    • Mark P. Mattson,
    • and Josephine M. Egan

    Exendin-4 Improves Glycemic Control, Ameliorates Brain and Pancreatic Pathologies, and Extends Survival in a Mouse Model of Huntington's Disease

    Diabetes February 2009 58:318-328; published ahead of print November 4, 2008, doi:10.2337/db08-0799
    • Myoung Sook Han,
    • Kun Wook Chung,
    • Hyae Gyeong Cheon,
    • Sang Dal Rhee,
    • Chang-Hwan Yoon,
    • Moon-Kyu Lee,
    • Kwang-Won Kim,
    • and Myung-Shik Lee

    Imatinib Mesylate Reduces Endoplasmic Reticulum Stress and Induces Remission of Diabetes in db/db Mice

    Diabetes February 2009 58:329-336; doi:10.2337/db08-0080
    • Jacob M. Haus,
    • Sangeeta R. Kashyap,
    • Takhar Kasumov,
    • Renliang Zhang,
    • Karen R. Kelly,
    • Ralph A. DeFronzo,
    • and John P. Kirwan

    Plasma Ceramides Are Elevated in Obese Subjects With Type 2 Diabetes and Correlate With the Severity of Insulin Resistance

    Diabetes February 2009 58:337-343; published ahead of print November 13, 2008, doi:10.2337/db08-1228
    • Ji-Hyun Lee,
    • Mi-Young Song,
    • Eun-Kyung Song,
    • Eun-Kyung Kim,
    • Woo Sung Moon,
    • Myung-Kwan Han,
    • Jin-Woo Park,
    • Kang-Beom Kwon,
    • and Byung-Hyun Park

    Overexpression of SIRT1 Protects Pancreatic β-Cells Against Cytokine Toxicity by Suppressing the Nuclear Factor-κB Signaling Pathway

    Diabetes February 2009 58:344-351; published ahead of print November 13, 2008, doi:10.2337/db07-1795
    • Dan Zheng,
    • Viorica Ionut,
    • Vahe Mooradian,
    • Darko Stefanovski,
    • and Richard N. Bergman

    Exenatide Sensitizes Insulin-Mediated Whole-Body Glucose Disposal and Promotes Uptake of Exogenous Glucose by the Liver

    Diabetes February 2009 58:352-359; published ahead of print November 14, 2008, doi:10.2337/db08-0875
    • Gail K. Adler,
    • Istvan Bonyhay,
    • Hannah Failing,
    • Elizabeth Waring,
    • Sarah Dotson,
    • and Roy Freeman

    Antecedent Hypoglycemia Impairs Autonomic Cardiovascular Function: Implications for Rigorous Glycemic Control

    Diabetes February 2009 58:360-366; published ahead of print December 3, 2008, doi:10.2337/db08-1153
    • Audrey Bergouignan,
    • Guy Trudel,
    • Chantal Simon,
    • Angèle Chopard,
    • Dale A. Schoeller,
    • Iman Momken,
    • Susanne B. Votruba,
    • Michel Desage,
    • Graham C. Burdge,
    • Guillemette Gauquelin-Koch,
    • Sylvie Normand,
    • and Stéphane Blanc

    Physical Inactivity Differentially Alters Dietary Oleate and Palmitate Trafficking

    Diabetes February 2009 58:367-376; published ahead of print November 18, 2008, doi:10.2337/db08-0263

Signal Transduction

    • Naofumi Fukuda,
    • Masahiro Emoto,
    • Yoshitaka Nakamori,
    • Akihiko Taguchi,
    • Sachiko Miyamoto,
    • Shinsuke Uraki,
    • Yoshitomo Oka,
    • and Yukio Tanizawa

    DOC2B: A Novel Syntaxin-4 Binding Protein Mediating Insulin-Regulated GLUT4 Vesicle Fusion in Adipocytes

    Diabetes February 2009 58:377-384; published ahead of print November 25, 2008, doi:10.2337/db08-0303

Obesity Studies

    • Emilio Ortega Martinez de Victoria,
    • Xiaoyuan Xu,
    • Juraj Koska,
    • Ann Marie Francisco,
    • Michael Scalise,
    • Anthony W. Ferrante, Jr.,
    • and Jonathan Krakoff

    Macrophage Content in Subcutaneous Adipose Tissue: Associations With Adiposity, Age, Inflammatory Markers, and Whole-Body Insulin Action in Healthy Pima Indians

    Diabetes February 2009 58:385-393; published ahead of print November 13, 2008, doi:10.2337/db08-0536

Immunology and Transplantation

    • Andréa Toma,
    • Taghrid Laïka,
    • Samy Haddouk,
    • Sandrine Luce,
    • Jean-Paul Briand,
    • Luc Camoin,
    • Francine Connan,
    • Marion Lambert,
    • Sophie Caillat-Zucman,
    • Jean-Claude Carel,
    • Sylviane Muller,
    • Jeannine Choppin,
    • François Lemonnier,
    • and Christian Boitard

    Recognition of Human Proinsulin Leader Sequence by Class I–Restricted T-Cells in HLA-A*0201 Transgenic Mice and in Human Type 1 Diabetes

    Diabetes February 2009 58:394-402; published ahead of print November 14, 2008, doi:10.2337/db08-0599

Islet Studies

    • Astrid C. Hauge-Evans,
    • Aileen J. King,
    • Danielle Carmignac,
    • Carolyn C. Richardson,
    • Iain C.A.F. Robinson,
    • Malcolm J. Low,
    • Michael R. Christie,
    • Shanta J. Persaud,
    • and Peter M. Jones

    Somatostatin Secreted by Islet δ-Cells Fulfills Multiple Roles as a Paracrine Regulator of Islet Function

    Diabetes February 2009 58:403-411; published ahead of print November 4, 2008, doi:10.2337/db08-0792
    • Nicolas Quoix,
    • Rui Cheng-Xue,
    • Laurine Mattart,
    • Ziad Zeinoun,
    • Yves Guiot,
    • Mélanie C. Beauvois,
    • Jean-Claude Henquin,
    • and Patrick Gilon

    Glucose and Pharmacological Modulators of ATP-Sensitive K+ Channels Control [Ca2+]c by Different Mechanisms in Isolated Mouse α-Cells

    Diabetes February 2009 58:412-421; published ahead of print November 13, 2008, doi:10.2337/db07-1298
    • Dan S. Luciani,
    • Kamila S. Gwiazda,
    • Ting-Lin B. Yang,
    • Tatyana B. Kalynyak,
    • Yaryna Bychkivska,
    • Matthew H.Z. Frey,
    • Kristin D. Jeffrey,
    • Arthur V. Sampaio,
    • T. Michael Underhill,
    • and James D. Johnson

    Roles of IP3R and RyR Ca2+ Channels in Endoplasmic Reticulum Stress and β-Cell Death

    Diabetes February 2009 58:422-432; published ahead of print November 25, 2008, doi:10.2337/db07-1762
    • Sapna Puri,
    • David A. Cano,
    • and Matthias Hebrok

    A Role for von Hippel-Lindau Protein in Pancreatic β-Cell Function

    Diabetes February 2009 58:433-441; published ahead of print November 25, 2008, doi:10.2337/db08-0749
    • Rita Bottino,
    • Angela Criscimanna,
    • Anna Casu,
    • Jing He,
    • Dirk J. Van der Windt,
    • William A. Rudert,
    • Carla Giordano,
    • and Massimo Trucco

    Recovery of Endogenous β-Cell Function in Nonhuman Primates After Chemical Diabetes Induction and Islet Transplantation

    Diabetes February 2009 58:442-447; published ahead of print November 10, 2008, doi:10.2337/db08-1127

Pathophysiology

    • Kathleen A. Page,
    • Jagriti Arora,
    • Maolin Qiu,
    • Rachna Relwani,
    • R. Todd Constable,
    • and Robert S. Sherwin

    Small Decrements in Systemic Glucose Provoke Increases in Hypothalamic Blood Flow Prior to the Release of Counterregulatory Hormones

    Diabetes February 2009 58:448-452; published ahead of print November 18, 2008, doi:10.2337/db08-1224
    • The HAPO Study Cooperative Research Group

    Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: Associations With Neonatal Anthropometrics

    Diabetes February 2009 58:453-459; published ahead of print November 14, 2008, doi:10.2337/db08-1112
    • Josep C. Jimenez-Chillaron,
    • Elvira Isganaitis,
    • Marika Charalambous,
    • Stephane Gesta,
    • Thais Pentinat-Pelegrin,
    • Ryan R. Faucette,
    • Jessica P. Otis,
    • Alice Chow,
    • Ruben Diaz,
    • Anne Ferguson-Smith,
    • and Mary-Elizabeth Patti

    Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

    Diabetes February 2009 58:460-468; published ahead of print November 18, 2008, doi:10.2337/db08-0490

Complications

    • Celine C. Berthier,
    • Hongyu Zhang,
    • MaryLee Schin,
    • Anna Henger,
    • Robert G. Nelson,
    • Berne Yee,
    • Anissa Boucherot,
    • Matthias A. Neusser,
    • Clemens D. Cohen,
    • Christin Carter-Su,
    • Lawrence S. Argetsinger,
    • Maria P. Rastaldi,
    • Frank C. Brosius,
    • and Matthias Kretzler

    Enhanced Expression of Janus Kinase–Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

    Diabetes February 2009 58:469-477; published ahead of print November 18, 2008, doi:10.2337/db08-1328

Genetics

    • Rong Rong,
    • Robert L. Hanson,
    • Daniel Ortiz,
    • Christopher Wiedrich,
    • Sayuko Kobes,
    • William C. Knowler,
    • Clifton Bogardus,
    • and Leslie J. Baier

    Association Analysis of Variation in/Near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B With Type 2 Diabetes and Related Quantitative Traits in Pima Indians

    Diabetes February 2009 58:478-488; published ahead of print November 13, 2008, doi:10.2337/db08-0877
    • Christine Dos Santos,
    • Pierre Bougnères,
    • and Delphine Fradin

    A Single-Nucleotide Polymorphism in a Methylatable Foxa2 Binding Site of the G6PC2 Promoter Is Associated With Insulin Secretion In Vivo and Increased Promoter Activity In Vitro

    Diabetes February 2009 58:489-492; published ahead of print November 4, 2008, doi:10.2337/db08-0587
    • Yasuharu Tabara,
    • Haruhiko Osawa,
    • Ryuichi Kawamoto,
    • Hiroshi Onuma,
    • Ikki Shimizu,
    • Tetsuro Miki,
    • Katsuhiko Kohara,
    • and Hideichi Makino

    Replication Study of Candidate Genes Associated With Type 2 Diabetes Based On Genome-Wide Screening

    Diabetes February 2009 58:493-498; published ahead of print November 25, 2008, doi:10.2337/db07-1785
    • Meredith A. Bostrom,
    • Barry I. Freedman,
    • Carl D. Langefeld,
    • Lingyi Liu,
    • Pamela J. Hicks,
    • and Donald W. Bowden

    Association of Adiponectin Gene Polymorphisms With Type 2 Diabetes in an African American Population Enriched for Nephropathy

    Diabetes February 2009 58:499-504; published ahead of print December 3, 2008, doi:10.2337/db08-0598
    • Nicholas J. Timpson,
    • Cecilia M. Lindgren,
    • Michael N. Weedon,
    • Joshua Randall,
    • Willem H. Ouwehand,
    • David P. Strachan,
    • N. William Rayner,
    • Mark Walker,
    • Graham A. Hitman,
    • Alex S.F. Doney,
    • Colin N.A. Palmer,
    • Andrew D. Morris,
    • Andrew T. Hattersley,
    • Eleftheria Zeggini,
    • Timothy M. Frayling,
    • and Mark I. McCarthy

    Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data

    Diabetes February 2009 58:505-510; published ahead of print December 3, 2008, doi:10.2337/db08-0906

Erratum

  • Erratum

    Diabetes February 2009 58:511; doi:10.2337/db09-er02
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This Issue

February 2009; 58 (2)
  1. Commentaries
  2. New Methodologies and Databases
  3. Metabolism
  4. Signal Transduction
  5. Obesity Studies
  6. Immunology and Transplantation
  7. Islet Studies
  8. Pathophysiology
  9. Complications
  10. Genetics
  11. Erratum

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