Advertisement

Table of Contents

April 2009; 58 (4)

Banting Lecture

    • Ralph A. DeFronzo

    From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

    Diabetes April 2009 58:773-795; doi:10.2337/db09-9028

Commentary

Commentaries

    • Edward H. Leiter

    Type 1 Diabetes Genes in Rats: Few or Many?

    Diabetes April 2009 58:796-797; doi:10.2337/db08-1811
    • Naveed Sattar and
    • Aroon D. Hingorani

    C-Reactive Protein and Prognosis in Diabetes: Getting to the Heart of the Matter

    Diabetes April 2009 58:798-799; doi:10.2337/db08-1788
    • Anna L. Gloyn,
    • Matthias Braun,
    • and Patrik Rorsman

    Type 2 Diabetes Susceptibility Gene TCF7L2 and Its Role in β-Cell Function

    Diabetes April 2009 58:800-802; doi:10.2337/db09-0099

Original Article

Metabolism

    • Yazmin Macotela,
    • Jeremie Boucher,
    • Thien T. Tran,
    • and C. Ronald Kahn

    Sex and Depot Differences in Adipocyte Insulin Sensitivity and Glucose Metabolism

    Diabetes April 2009 58:803-812; published ahead of print January 9, 2009, doi:10.2337/db08-1054
    • Ronit Katz,
    • Matthew J. Budoff,
    • Junichiro Takasu,
    • David M. Shavelle,
    • Alain Bertoni,
    • Roger S. Blumenthal,
    • Pamela Ouyang,
    • Nathan D. Wong,
    • and Kevin D. O'Brien

    Relationship of Metabolic Syndrome With Incident Aortic Valve Calcium and Aortic Valve Calcium Progression: The Multi-Ethnic Study of Atherosclerosis (MESA)

    Diabetes April 2009 58:813-819; published ahead of print January 9, 2009, doi:10.2337/db08-1515
    • Oscar Escribano,
    • Carlos Guillén,
    • Carmen Nevado,
    • Almudena Gómez-Hernández,
    • C. Ronald Kahn,
    • and Manuel Benito

    β-Cell Hyperplasia Induced by Hepatic Insulin Resistance: Role of a Liver-Pancreas Endocrine Axis Through Insulin Receptor A Isoform

    Diabetes April 2009 58:820-828; published ahead of print January 9, 2009, doi:10.2337/db08-0551
    • Gregory R. Steinberg,
    • Matthew J. Watt,
    • Matthias Ernst,
    • Morris J. Birnbaum,
    • Bruce E. Kemp,
    • and Sebastian Beck Jørgensen

    Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase–Dependent Pathway That Is Impaired With Obesity

    Diabetes April 2009 58:829-839; published ahead of print January 9, 2009, doi:10.2337/db08-0659
    • Gavin A. Bewick,
    • Aysha Kent,
    • Daniel Campbell,
    • Michael Patterson,
    • Mohammed A. Ghatei,
    • Stephen R. Bloom,
    • and James V. Gardiner

    Mice With Hyperghrelinemia Are Hyperphagic and Glucose Intolerant and Have Reduced Leptin Sensitivity

    Diabetes April 2009 58:840-846; published ahead of print January 16, 2009, doi:10.2337/db08-1428
    • Håkan K.R. Karlsson,
    • Alexander V. Chibalin,
    • Heikki A. Koistinen,
    • Jing Yang,
    • Francoise Koumanov,
    • Harriet Wallberg-Henriksson,
    • Juleen R. Zierath,
    • and Geoffrey D. Holman

    Kinetics of GLUT4 Trafficking in Rat and Human Skeletal Muscle

    Diabetes April 2009 58:847-854; published ahead of print February 2, 2009, doi:10.2337/db08-1539

Obesity Studies

    • Maryam Ahmadian,
    • Robin E. Duncan,
    • Krista A. Varady,
    • Danubia Frasson,
    • Marc K. Hellerstein,
    • Andreas L. Birkenfeld,
    • Varman T. Samuel,
    • Gerald I. Shulman,
    • Yuhui Wang,
    • Chulho Kang,
    • and Hei Sook Sul

    Adipose Overexpression of Desnutrin Promotes Fatty Acid Use and Attenuates Diet-Induced Obesity

    Diabetes April 2009 58:855-866; published ahead of print January 9, 2009, doi:10.2337/db08-1644
    • Jenny M. Kindblom,
    • Mattias Lorentzon,
    • Åsa Hellqvist,
    • Lars Lönn,
    • John Brandberg,
    • Staffan Nilsson,
    • Ensio Norjavaara,
    • and Claes Ohlsson

    BMI Changes During Childhood and Adolescence as Predictors of Amount of Adult Subcutaneous and Visceral Adipose Tissue in Men: The GOOD Study

    Diabetes April 2009 58:867-874; published ahead of print January 23, 2009, doi:10.2337/db08-0606

Islet Studies

    • Nathalie Fiaschi-Taesch,
    • Todd A. Bigatel,
    • Brian Sicari,
    • Karen K. Takane,
    • Fatima Salim,
    • Silvia Velazquez-Garcia,
    • George Harb,
    • Karen Selk,
    • Irene Cozar-Castellano,
    • and Andrew F. Stewart

    Survey of the Human Pancreatic β-Cell G1/S Proteome Reveals a Potential Therapeutic Role for Cdk-6 and Cyclin D1 in Enhancing Human β-Cell Replication and Function In Vivo

    Diabetes April 2009 58:882-893; published ahead of print January 9, 2009, doi:10.2337/db08-0631
    • Gabriela da Silva Xavier,
    • Merewyn K. Loder,
    • Angela McDonald,
    • Andrei I. Tarasov,
    • Raffaella Carzaniga,
    • Katrin Kronenberger,
    • Sebastian Barg,
    • and Guy A. Rutter

    TCF7L2 Regulates Late Events in Insulin Secretion From Pancreatic Islet β-Cells

    Diabetes April 2009 58:894-905; published ahead of print January 23, 2009, doi:10.2337/db08-1187
    • Aleksey V. Matveyenko,
    • Tatyana Gurlo,
    • Marie Daval,
    • Alexandra E. Butler,
    • and Peter C. Butler

    Successful Versus Failed Adaptation to High-Fat Diet–Induced Insulin Resistance: The Role of IAPP-Induced β-Cell Endoplasmic Reticulum Stress

    Diabetes April 2009 58:906-916; published ahead of print January 16, 2009, doi:10.2337/db08-1464

Complications

    • Yugal Behl,
    • Padmaja Krothapalli,
    • Tesfahun Desta,
    • Sayon Roy,
    • and Dana T. Graves

    FOXO1 Plays an Important Role in Enhanced Microvascular Cell Apoptosis and Microvascular Cell Loss in Type 1 and Type 2 Diabetic Rats

    Diabetes April 2009 58:917-925; published ahead of print January 23, 2009, doi:10.2337/db08-0537
    • Graziella Bruno,
    • Paolo Fornengo,
    • Giulia Novelli,
    • Francesco Panero,
    • Massimo Perotto,
    • Olivia Segre,
    • Chiara Zucco,
    • PierCarlo Deambrogio,
    • Giuseppe Bargero,
    • and Paolo Cavallo Perin

    C-Reactive Protein and 5-Year Survival in Type 2 Diabetes: The Casale Monferrato Study

    Diabetes April 2009 58:926-933; published ahead of print December 15, 2008, doi:10.2337/db08-0900
    • George Francis,
    • Jose Martinez,
    • Wei Liu,
    • Thuhien Nguyen,
    • Amit Ayer,
    • Jared Fine,
    • Douglas Zochodne,
    • Leah R. Hanson,
    • William H. Frey II,
    • and Cory Toth

    Intranasal Insulin Ameliorates Experimental Diabetic Neuropathy

    Diabetes April 2009 58:934-945; published ahead of print January 9, 2009, doi:10.2337/db08-1287
    • Pairoj Rerkpattanapipat,
    • Ralph B. D'Agostino, Jr,
    • Kerry M. Link,
    • Eyal Shahar,
    • Joao A. Lima,
    • David A. Bluemke,
    • Shantanu Sinha,
    • David M. Herrington,
    • and W. Gregory Hundley

    Location of Arterial Stiffening Differs in Those With Impaired Fasting Glucose Versus Diabetes: Implications for Left Ventricular Hypertrophy From the Multi-Ethnic Study of Atherosclerosis

    Diabetes April 2009 58:946-953; published ahead of print January 9, 2009, doi:10.2337/db08-1192
    • Zhi Zheng,
    • Haibing Chen,
    • Genjie Ke,
    • Ying Fan,
    • Haidong Zou,
    • Xiaodong Sun,
    • Qing Gu,
    • Xun Xu,
    • and Patrick C.P. Ho

    Protective Effect of Perindopril on Diabetic Retinopathy Is Associated With Decreased Vascular Endothelial Growth Factor–to–Pigment Epithelium–Derived Factor Ratio: Involvement of a Mitochondria–Reactive Oxygen Species Pathway

    Diabetes April 2009 58:954-964; published ahead of print February 2, 2009, doi:10.2337/db07-1524

Pharmacology and Therapeutics

    • Jung Hwan Hwang,
    • Dong Wook Kim,
    • Eun Jin Jo,
    • Yong Kyung Kim,
    • Young Suk Jo,
    • Ji Hoon Park,
    • Sang Ku Yoo,
    • Myung Kyu Park,
    • Tae Hwan Kwak,
    • Young Lim Kho,
    • Jin Han,
    • Hueng-Sik Choi,
    • Sang-Hee Lee,
    • Jin Man Kim,
    • InKyu Lee,
    • Taeyoon Kyung,
    • Cholsoon Jang,
    • Jongkyeong Chung,
    • Gi Ryang Kweon,
    • and Minho Shong

    Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice

    Diabetes April 2009 58:965-974; published ahead of print January 9, 2009, doi:10.2337/db08-1183
    • Mohammad Hossein Noyan-Ashraf,
    • M. Abdul Momen,
    • Kiwon Ban,
    • Al-Muktafi Sadi,
    • Yu-Qing Zhou,
    • Ali M. Riazi,
    • Laurie L. Baggio,
    • R. Mark Henkelman,
    • Mansoor Husain,
    • and Daniel J. Drucker

    GLP-1R Agonist Liraglutide Activates Cytoprotective Pathways and Improves Outcomes After Experimental Myocardial Infarction in Mice

    Diabetes April 2009 58:975-983; published ahead of print January 16, 2009, doi:10.2337/db08-1193

Genetics

    • Helmut Laumen,
    • Akuma D. Saningong,
    • Iris M. Heid,
    • Jochen Hess,
    • Christian Herder,
    • Melina Claussnitzer,
    • Jens Baumert,
    • Claudia Lamina,
    • Wolfgang Rathmann,
    • Eva-Maria Sedlmeier,
    • Norman Klopp,
    • Barbara Thorand,
    • H.-Erich Wichmann,
    • Thomas Illig,
    • and Hans Hauner

    Functional Characterization of Promoter Variants of the Adiponectin Gene Complemented by Epidemiological Data

    Diabetes April 2009 58:984-991; published ahead of print December 15, 2008, doi:10.2337/db07-1646
    • Dennis O. Mook-Kanamori,
    • Eric A.P. Steegers,
    • Andre G. Uitterlinden,
    • Henriëtte A. Moll,
    • Cornelia M. van Duijn,
    • Albert Hofman,
    • and Vincent W.V. Jaddoe

    Breast-Feeding Modifies the Association of PPARγ2 Polymorphism Pro12Ala With Growth in Early Life: The Generation R Study

    Diabetes April 2009 58:992-998; published ahead of print February 2, 2009, doi:10.2337/db08-1311
    • David J. Friedman,
    • Matthew E. Talbert,
    • Donald W. Bowden,
    • Barry I. Freedman,
    • Yves Mukanya,
    • Keiichi Enjyoji,
    • and Simon C. Robson

    Functional ENTPD1 Polymorphisms in African Americans With Diabetes and End-Stage Renal Disease

    Diabetes April 2009 58:999-1006; published ahead of print December 18, 2008, doi:10.2337/db08-1214
    • Robert H. Wallis,
    • KeSheng Wang,
    • Leili Marandi,
    • Eugene Hsieh,
    • Terri Ning,
    • Gary Y.C. Chao,
    • Janice Sarmiento,
    • Andrew D. Paterson,
    • and Philippe Poussier

    Type 1 Diabetes in the BB Rat: A Polygenic Disease

    Diabetes April 2009 58:1007-1017; published ahead of print January 23, 2009, doi:10.2337/db08-1215
    • Patrick Concannon,
    • Wei-Min Chen,
    • Cécile Julier,
    • Grant Morahan,
    • Beena Akolkar,
    • Henry A. Erlich,
    • Joan E. Hilner,
    • Jørn Nerup,
    • Concepcion Nierras,
    • Flemming Pociot,
    • John A. Todd,
    • Stephen S. Rich,
    • and the Type 1 Diabetes Genetics Consortium

    Genome-Wide Scan for Linkage to Type 1 Diabetes in 2,496 Multiplex Families From the Type 1 Diabetes Genetics Consortium

    Diabetes April 2009 58:1018-1022; published ahead of print January 9, 2009, doi:10.2337/db08-1551

Brief Report

Immunology and Transplantation

    • Andrea Valle,
    • Tatiana Jofra,
    • Angela Stabilini,
    • Mark Atkinson,
    • Maria-Grazia Roncarolo,
    • and Manuela Battaglia

    Rapamycin Prevents and Breaks the Anti-CD3–Induced Tolerance in NOD Mice

    Diabetes April 2009 58:875-881; published ahead of print January 16, 2009, doi:10.2337/db08-1432

Genetics

    • Andrea K. Steck,
    • Weiming Zhang,
    • Teodorica L. Bugawan,
    • Katherine J. Barriga,
    • Alan Blair,
    • Henry A. Erlich,
    • George S. Eisenbarth,
    • Jill M. Norris,
    • and Marian J. Rewers

    Do Non-HLA Genes Influence Development of Persistent Islet Autoimmunity and Type 1 Diabetes in Children With High-Risk HLA-DR,DQ Genotypes?

    Diabetes April 2009 58:1028-1033; published ahead of print February 2, 2009, doi:10.2337/db08-1179

Brief Reports

Genetics

    • Congrong Wang,
    • Cheng Hu,
    • Rong Zhang,
    • Yuqian Bao,
    • Xiaojing Ma,
    • Jingyi Lu,
    • Wen Qin,
    • Xinyu Shao,
    • Junxi Lu,
    • Jing Xu,
    • Huijuan Lu,
    • Kunsan Xiang,
    • and Weiping Jia

    Common Variants of Hepatocyte Nuclear Factor 1β Are Associated With Type 2 Diabetes in a Chinese Population

    Diabetes April 2009 58:1023-1027; published ahead of print January 23, 2009, doi:10.2337/db08-1064

Organization Section

  • Organization Section

    Diabetes April 2009 58:1034

Online Letters to the Editor

Online Letters

    • Haim Shapiro,
    • Pierre Singer,
    • and Joelle Attal-Singer

    Comment on: Reyna et al. (2008) Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects. Diabetes 57:2595–2602

    Diabetes April 2009 58:e5; doi:10.2337/db09-0022
    • Sara M. Reyna,
    • Sangeeta Ghosh,
    • Ralph A. DeFronzo,
    • Christopher P. Jenkinson,
    • and Nicolas Musi

    Response to Comment on: Reyna et al. (2008) Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects. Diabetes 57:2595–2602

    Diabetes April 2009 58:e6-e7; doi:10.2337/db09-0077
|

This Issue

April 2009; 58 (4)
  1. Banting Lecture
  2. Commentary
    1. Commentaries
  4. Original Article
    1. Metabolism
    2. Obesity Studies
    3. Islet Studies
    4. Complications
    5. Pharmacology and Therapeutics
    6. Genetics
  6. Brief Report
    1. Immunology and Transplantation
    2. Genetics
  8. Brief Reports
    1. Genetics
  10. Organization Section
  11. Online Letters to the Editor
    1. Online Letters

Find articles in this issue containing these words:

Current Issue

  1. February 2012, 61 (2)
  1. Current Issue
  1. Alert me to new issues of Diabetes
Advertisement