Majority of Children With Type 1 Diabetes Produce and Deposit Anti-Tissue Transglutaminase Antibodies in the Small Intestine

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FIG. 3.
FIG. 3.

Monkey esophagus sections stained with anti-TG2 scFv containing a VH1, VH3, and VH4 gene segment. An anti-TG2 VH5 scFv is shown as a control. All of the scFvs recognize native TG2–anti-endomysium structures in the oesophagus muscularis mucosa according to the reticular motif, which is similar to the results observed for serum anti-endomysium antibodies. (A high-quality digital representation of this figure is available in the online issue.)

This Article

  1. Diabetes vol. 58 no. 7 1578-1584