|Group A||Group B||P|
|CD3+ >34/mm||6/14 (43)||4/19 (21)||NS|
|γδ+ >3.4/mm||9/14 (64)||5/19 (26)||<0.05|
|CD25+ >4/mm2||4/14 (29)||7/19 (37)||NS|
|HLA-DR (++/+++)||10/14 (71)||11/19 (58)||NS|
|ICAM-1 (++/+++)||4/14 (29)||6/19 (31)||NS|
Group A consisted of type 1 diabetic patients with elevated serum levels of anti-TG2 antibodies (TG2+). Group B consisted of type 1 diabetic patients with normal serum levels of anti-TG2 antibodies (TG2−). CD3+ and γδ+ IELs are expressed per millimeter of epithelium; CD25+ cells are expressed per square millimeter of lamina propria. The expression of crypt epithelial HLA-DR and the expression of lamina propria ICAM-1 were evaluated in terms of their staining intensity and graded on an arbitrary scale of staining level, where − = no staining, + = weak staining, ++ = strong staining, and +++ = very strong staining. The data were analyzed by a χ2 test. P < 0.05 was considered significant.