Majority of Children With Type 1 Diabetes Produce and Deposit Anti-Tissue Transglutaminase Antibodies in the Small Intestine

TABLE 2

Prevalence of IgA anti-TG2 mucosal deposits in the study population

Patients Presence of anti-TG2 mucosal deposits % Positivity
Type 1 diabetic patients
    TG2+ 11/14 78
    TG 11/19 58
Patients with untreated celiac disease 12/12 100
Control subjects 4/28 14
Patients with IBD 3/18 16.6
Patients with food allergies 0/9 0
  • TG2+ type 1 diabetic patients had increased serum levels of anti-TG2 antibodies; TG2 type 1 diabetic patients had normal serum levels of anti-TG2 antibodies.

This Article

  1. Diabetes vol. 58 no. 7 1578-1584