Impact of Physical Inactivity on Subcutaneous Adipose Tissue Metabolism in Healthy Young Male Offspring of Patients With Type 2 Diabetes

TABLE 1

Subject characteristics

Before bed rest After bed rest
CON FDR aP CON FDR bP cP
Age (years) 25 ± 0.2 26.1 ± 1 ns nm nm
VO2max (ml O2/kg/min) 43.5 ± 1.5 39.1 ± 1.9 ns 42.8 ± 1.1 37.5 ± 2.0 ns ns
VO2max (ml/min) 3,659 ± 125 3,405 ± 162 P < 0.05 3,527 ± 101 3,190 ± 160 ns ns
Fasting arterial glucose (mmol/l) 5.3 ± 0.1 5.5 ± 0.1 ns 5.1 ± 0.1 5.2 ± 0.1 P < 0.05 P < 0.05
Weight (kg) 82.5 ± 2.3 84.0 ± 3.3 ns 82.2 ± 2.3 83.6 ± 3.2 ns ns
Height (m) 1.85 ± 0.01 1.84 ± 0.02 ns nm nm
BMI (kg/m2) 24.1 ± 0.5 24.9 ± 0.9 ns 23.9 ± 0.5 24.8 ± 0.9 ns ns
Total fat mass (kg) 14.3 ± 1.6 21.6 ± 2.5 P < 0.05 14.7 ± 1.8 21.5 ± 2.7 ns ns
Total lean mass (kg) 63.8 ± 1.1 58.6 ± 1.5 P < 0.05 63.6 ± 1.1 58.4 ± 1.5 ns ns
Whole body fat percentage (%) 17.4 ± 1.7 25.0 ± 2.3 P < 0.05 17.1 ± 1.6 24.9 ± 2.5 ns ns
Trunk fat mass/total fat mass 0.48 ± 0.1 0.58 ± 0.001 P < 0.05 0.50 ± 0.01 0.58 ± 0.01 ns ns
Leg fat mass/total fat mass 0.37 ± 0.1 0.29 ± 0.01 P < 0.05 0.37 ± 0.01 0.29 ± 0.01 ns ns
Waist/hip ratio 0.85 ± 0.01 0.88 ± 0.02 ns 0.86 ± 0.01 0.87 ± 0.02 ns ns
Abdominal skinfold (mm) 21 ± 1.8 25 ± 3.0 ns 21 ± 1.6 23 ± 2.0 ns ns
Femoral skinfold (mm) 16 ± 1.5 16 ± 2.0 ns 15 ± 1.4 16 ± 2.0 ns ns
  • Data are mean ± SE.

  • aP, significant difference between the groups before bed rest (P < 0.05).

  • bP, significant difference before vs. after bed rest within CON, P < 0.05.

  • cP, significant difference before vs. after bed rest within FDR, P < 0.05. ns, not significant; nm, not measured.

This Article

  1. Diabetes vol. 59 no. 11 2790-2798