Impact of Physical Inactivity on Subcutaneous Adipose Tissue Metabolism in Healthy Young Male Offspring of Patients With Type 2 Diabetes

TABLE 4

Plasma glucose, glycerol, lactate, FFA, triglyceride, and insulin

CON FDR
Before bed rest After bed rest Before bed rest After bed rest
n 20 20 13 13
P glucose (mM) Basal 5.1 ± 0.06* 4.8 ± 0.05* 5.4 ± 0.1* 5.2 ± 0.1*
P glucose (mM) Insulin stimulated 4.9 ± 0.07* 4.8 ± 0.07 5.3 ± 0.1* 55.1 ± 0.09*
P glycerol (μM)** Basal 34.6 ± 2.7 31.2 ± 2.1 38.5 ± 3.7 34.2 ± 2.9
P glycerol (μM)** Insulin stimulated 14.5 ± 0.9 13.9 ± 0.9 14.7 ± 1.2 13.0 ± 1.0
P lactate (mM) Basal 0.7 ± 0.05 0.7 ± 0.05 0.7 ± 0.07 0.8 ± 0.05
P lactate (mM) Insulin stimulated 0.9 ± 0.05 0.8 ± 0.04* 0.7 ± 0.06 0.6 ± 0.03*
P FFA (μM) Basal 264 ± 30* 282 ± 30 369 ± 46* 307 ± 36
P FFA (μM) Insulin stimulated 13 ± 2* 11 ± 2 26 ± 5* 20 ± 3
P triglyceride (mM) Basal 0.9 ± 0.1* 1.0 ± 0.1* 1.1 ± 0.1* 1.3 ± 0.1*
P triglyceride (mM) Insulin stimulated 0.5 ± 0.05 0.6 ± 0.1 0.7 ± 0.1 1.1 ± 0.1
P insulin (pM) Basal 35 ± 3* 35 ± 3* 50 ± 8* 47 ± 5*
P insulin (pM) Insulin stimulated 294 ± 10 272 ± 13 287 ± 26 308 ± 22
  • Data are presented as mean ± SE.

  • *Significant difference CON vs. FDR, P < 0.05.

  • †Significant difference before vs. after bed rest within the group; P < 0.05.

  • ‡Significant difference basal vs. insulin-stimulated state within the group on the specified day, P < 0.05.

  • **Data were log transformed before statistical test.

This Article

  1. Diabetes vol. 59 no. 11 2790-2798