Protein Farnesylation–Dependent Raf/Extracellular Signal–Related Kinase Signaling Links to Cytoskeletal Remodeling to Facilitate Glucose-Induced Insulin Secretion in Pancreatic β-Cells
- Anjaneyulu Kowluru1,
- Rajakrishnan Veluthakal1,
- Christopher J. Rhodes2,
- Vasudeva Kamath1,
- Ismail Syed1 and
- Brandon J. Koch1
- 1Department of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University and β-Cell Biochemistry Laboratory, John D. Dingell VA Medical Center, Detroit, Michigan;
- 2Kovler Diabetes Center, Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, The University of Chicago, Chicago, Illinois.
- Corresponding author: Anjaneyulu Kowluru, .