Changes in Alcohol Consumption and Subsequent Risk of Type 2 Diabetes in Men

TABLE 3

Hazard ratios of type 2 diabetes according to updated 4-year changes in initial and current drinking category (n = 38,031)

Initial alcohol drinking category (g/day) Alcohol drinking category 4 years later (g/day) Ptrend*
Light (0–4.9) Moderate (5.0–29.9) Heavier (≥30.0)
Light (0–4.9)
    Multivariable-adjusted 1.00 [Reference] 0.75 (0.62–0.90) 0.35 (0.11–1.10) <0.001
    Person-years 169,623 31,723 1,127
    Number of cases 875 125 3
Moderate (5.0–29.9)
    Multivariable-adjusted 1.09 (0.92–1.30) 0.74 (0.65–0.83) 0.59 (0.45–0.77) <0.001
    Person-years 27,841 134,942 16,050
    Number of cases 159 496 60
Heavier (≥30.0)
    Multivariable-adjusted 0.78 (0.44–1.38) 0.67 (0.52–0.88) 0.50 (0.40–0.63) 0.08
    Person-years 2,089 15,036 30,067
    Number of cases 12 65 110
  • *Ptrend values were derived from tests of linear trend across increasing categories of alcohol use by treating the median value of each category as a continuous variable.

  • †Hazard ratios (95% CIs) were calculated using Cox proportional hazards model and adjusted for the covariates listed in Table 2.

This Article

  1. Diabetes vol. 60 no. 1 74-79