Changes in Alcohol Consumption and Subsequent Risk of Type 2 Diabetes in Men

TABLE 4

Associations of a 7.5 g/day increment in alcohol consumption from 1990–1994 on subsequent total adiponectin and hemoglobin A1c levels, classified by alcohol consumption in 1990

Alcohol consumption in 1990 (g/day) Mean increment in glycemic marker per 7.5 g/day increase in alcohol consumption from 1990–1994
Total adiponectin (μg/ml) HbA1c (%)
Non (0)
    Mean increment* 1.2 ± 0.3 −0.04 ± 0.02
    Number of participants 151 267
<1 drink/day (0.1–14.9)
    Mean increment* 0.5 ± 0.3 −0.02 ± 0.02
    Number of participants 355 610
≥1 drink/day (≥15.0)
    Mean increment* −0.6 ± 0.3 0.01 ± 0.01
    Number of participants 191 311
    Pinteraction 0.002 0.02
  • *Values are mean increments (± SEM) per 7.5 g/day increment in alcohol consumption over 4 years and were calculated with a mixed ANOVA model that included terms for age, BMI, physical activity, smoking status, family history of type 2 diabetes, hypertension, hypercholesterolemia, cardiovascular disease, dietary glycemic load, fiber intake, trans fat intake, ratio of polyunsaturated fat and saturated fat (all energy-adjusted), coffee intake, total energy intake, and case-control status.

  • Pinteraction value was derived by adding an interaction term between the 7.5 g/day increment of alcohol consumption (continuous), and initial alcohol consumption in 1990 (categorical) in the mixed ANOVA model.

This Article

  1. Diabetes vol. 60 no. 1 74-79