Prospectively Determined Impact of Type 1 Diabetes on Brain Volume During Development

TABLE 3

Whole brain gray and white volume at each time point for NDC and T1DM groups and T1DM subgroups (in milliliters)

NDC T1DM No hypo Any hypo HbA1c (%)
<7.5 7.5–8.9 ≥9
n 25 75 49 19 15 44 16
Whole brain gray volume
 Time 1 820.09 (82.09) 853.94 (74.24) 859.51 (78.75) 847.94 (57.77) 873.42 (86.45) 854.96 (63.92) 832.89 (87.43)
 Time 2 809.87 (81.75) 844.84 (75.97) 850.72 (81.99) 838.81 (54.94) 863.63 (86.31) 849.16 (66.02) 815.36 (87.69)
Whole brain white volume
 Time 1 448.16 (51.11) 466.69 (49.48) 472.81 (52.94) 457.32 (40.34) 481.49 (53.02) 462.38 (44.11) 464.66 (60.00)
 Time 2 452.18 (49.18) 471.71 (50.29) 451.16 (43.16) 461.27 (40.21) 484.39 (50.55) 469.48 (46.40) 465.98 (60.90)
  • Data are means (SD) unless otherwise indicated. Hypo, hypoglycemia.

This Article

  1. Diabetes vol. 60 no. 11 3006-3014