Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness

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FIG. 1.
FIG. 1.

mRNA expression of IRS2 in monocytes from FDRs of type 2 diabetic subjects is correlated with in vivo insulin resistance and subclinical atherosclerosis. High log IRS2 mRNA levels are associated with increased levels of M (A), decreased IMT (B), decreased fasting plasma glucose levels (C), decreased glycated hemoglobin (D), and increased HDL cholesterol (E). *P < 0.05 for LOW IRS2 (n = 14) compared with HIGH IRS2 (n = 14) by ANOVA with Bonferroni post-hoc test.

This Article

  1. Diabetes vol. 60 no. 12 3265-3270