Response to Comment on: Atkinson. It's Time to Consider Changing the Rules: The Rationale for Rethinking Control Groups in Clinical Trials Aimed at Reversing Type 1 Diabetes. Diabetes 2011;60:361–363

  1. Mark A. Atkinson
  1. From the Departments of Pathology and Pediatrics, University of Florida, Gainesville, Florida
  1. Corresponding author: Mark A. Atkinson, atkinson{at}

In 2003, the President of the United States introduced a now often used phrase into the American lexicon, “Mission accomplished” (1). While history has not judged, to the greatest of degrees, his proclamation with favor in terms of its accuracy, the idiom does seem a fitting response to the letter by Sanda and Greenbaum (2), written in reaction to my editorial (3). This claim can effectively be made as their action is exactly what I hoped would occur: an open discourse…a debate, on how trials to reverse type 1 diabetes are designed and …

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