31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism
(Downloading may take up to 30 seconds. If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.
The 31P-ST technique can be applied in human muscle in vivo to assess the unidirectional fluxes that contribute to phosphate-exchange
reactions. Irradiating the γATP peak with a frequency-selective saturation pulse leads to a reduction in the phosphocreatine
(ΔPCr) and inorganic phosphate (ΔPi) signals due to phosphate exchange via CK or the ATP synthesis/hydrolysis cycle.