31P-Magnetization Transfer Magnetic Resonance Spectroscopy Measurements of In Vivo Metabolism

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FIG. 1.
FIG. 1.

The 31P-ST technique can be applied in human muscle in vivo to assess the unidirectional fluxes that contribute to phosphate-exchange reactions. Irradiating the γATP peak with a frequency-selective saturation pulse leads to a reduction in the phosphocreatine (ΔPCr) and inorganic phosphate (ΔPi) signals due to phosphate exchange via CK or the ATP synthesis/hydrolysis cycle.

This Article

  1. Diabetes vol. 61 no. 11 2669-2678