Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior

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FIG. 2.
FIG. 2.

Effect of fat enrichment with MUFAs and SFAs on serum parameters and visceral body fat mass. NEFA (A), HDL, LDL, cholesterol (CHOL), triglycerides (TG) (B), leptin (C), and adiponectin (D) of MUFA- (gray bars, n = 14), SFA- (black bars, n = 14), and chow-fed (white bars, n = 24) animals in the fasted state. Significance is indicated for fat-enriched diets to controls: *P < 0.05 and **P < 0.005. E: Magnetic resonance images of total (TAT) and visceral fat (VAT) deposits in mice fed an SFA-enriched, MUFA-enriched, or chow diet. Bright (hyperintense) areas represent fat tissue. Calculated volumes of TAT and VAT integrated over 24 such slices are quantified of n = 9 mice per diet group. Significance is indicated for fat-enriched diets to controls: *P < 0.05 and ***P < 0.001.

This Article

  1. Diabetes vol. 61 no. 7 1669-1679