Effects of Hyperglycemia and Effects of Ketosis on Cerebral Perfusion, Cerebral Water Distribution, and Cerebral Metabolism

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FIG. 1.
FIG. 1.

A: CBF in hyperglycemic and ketotic rats in comparison with control rats measured using arterial spin labeling (means ± SE for 10 ketotic, 10 control, and 9 hyperglycemic rats). Cortex: P = 0.03 hyperglycemic vs. control, P = 0.02 ketotic vs. control. Striatum: P = 0.06 hyperglycemic vs. control, P = 0.07 ketotic vs. control. B: Apparent diffusion coefficients in hyperglycemic rats and ketotic rats in comparison with control rats (means ± SE for 10 ketotic and 10 control rats and 9 hyperglycemic rats). Cortex: P = 0.004 hyperglycemic vs. control, P = 0.012 ketotic vs. control. Striatum: P = 0.019 hyperglycemic vs. control, P = 0.46 ketotic vs. control.

This Article

  1. Diabetes vol. 61 no. 7 1831-1837