Comment on: Sørensen et al. Maternal Serum Levels of 25-Hydroxy-Vitamin D During Pregnancy and Risk of Type 1 Diabetes in the Offspring. Diabetes 2012;61:175–178

  1. Suvi M. Virtanen1
  1. 1Nutrition Unit, National Institute for Health and Welfare, Helsinki, Finland
  2. 2Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland
  1. Corresponding author: Sari Niinistö, sari.niinisto{at}thl.fi.

Sørensen et al. (1) report that in Norway, low concentration of 25-hydroxy-vitamin D [25(OH)D] in mothers during pregnancy was associated with an increased risk of type 1 diabetes in the offspring. We would like to point out that one putative confounding factor in their study might have been the intake of n-3 polyunsaturated fatty acids. Childhood n-3 fatty acid intake and status have been linked with the development of pretype 1 diabetes (2), while reasonably powered prospective studies of exposure during pregnancy are …

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