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Cover: Illustration showing the progress of diabetic neuropathy. At top is a normal neuron with an adequate blood supply. Blood vessels serving the middle neuron have become diseased and the neuron is becoming damaged. The neuron at the bottom has shriveled as the blood vessels disappear. Carol and Mike Werner/Science Source. For more information, please visit Science Source

This issue of Diabetes features an article by Lupachyk et al. on the role of endoplasmic reticulum stress in diabetic neuropathy, p. 944, and an accompanying commentary, p. 696.

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