Circadian Regulation of Lipid Mobilization in White Adipose Tissues

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FIG. 3.
FIG. 3.

Circadian clock controls TG metabolism in WAT. A: mRNA levels of genes involved in adipocyte TG metabolism from wild-type (WT) WAT samples isolated at two opposite circadian time points, 37 h (open bars) and 49 h (closed bars) in DD (n = 3 per time point [*P < 0.05; **P < 0.01 by unpaired t test]). Circadian expression profiles of candidate genes from (A) involved in FFA transport (B) and TG synthesis (C) in WAT samples from WT (closed circles) and ClockΔ19 (open circles) mice in DD (n = 3/time point [*P < 0.05; **P < 0.01; ***P < 0.001 by two-way ANOVA with Bonferroni posttest]). All data are shown as means ± SEM.

This Article

  1. Diabetes vol. 62 no. 7 2195-2203