Circadian Regulation of Lipid Mobilization in White Adipose Tissues
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Aberrant fasting responses in ClockΔ19 mice. Serum FFA (A) and glycerol (B) levels after 12 and 24 h of food deprivation in wild-type (WT; closed bars) and ClockΔ19 (open bars) mice (n = 3–5/time point). C: Normalized changes in liver glycogen content of WT and ClockΔ19 mice during 12-h fasting (n = 3 to 4). D: Rectal temperature in WT and ClockΔ19 animals during 12-h fasting (n = 6–12). All data are shown as means ± SEM. *P < 0.05; ***P < 0.001 by two-way ANOVA with Bonferroni posttest; #P < 0.001 by unpaired t test.