Microphthalmia Transcription Factor Regulates Pancreatic β-Cell Function

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FIG. 3.
FIG. 3.

Wild-type (wt/het) and Mitfce/ce mutant islets consist of insulin, glucagon, somatostatin, and PP cells (A). B: Average β-cell area is unchanged in Mitfce/ce animals; n = 3. C: Quantitative RT-PCR measurement of pancreatic hormone levels in Mitf mutant and wild-type islets (n > 5 per genotype.) The data were normalized to HPRT mRNA levels and are presented as relative to control (set as 1). t test, *P < 0.05, ***P < 0.001.

This Article

  1. Diabetes vol. 62 no. 8 2834-2842