Microphthalmia Transcription Factor Regulates Pancreatic β-Cell Function

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FIG. 5.
FIG. 5.

Quantitative gene expression profile of pancreatic transcription factors and glucose metabolism–related (A) and insulin secretory (B) genes in Mitf mutant (Mitfce/ce) and wild-type (wt/het) islets (n ≥ 4 per genotype). The data were normalized to HPRT mRNA and are presented relative to control (set to 1). IA-2, insulinoma-associated protein-2; IAPP, islet amyloid polypeptide. ***P < 0.001.

This Article

  1. Diabetes vol. 62 no. 8 2834-2842