Improvement in β-Cell Secretory Capacity After Human Islet Transplantation According to the CIT07 Protocol
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Plasma glucose (A) and glucose infusion rates (B) during conduct of the glucose-potentiated arginine test, and insulin (C) and C-peptide (D) levels in response to bolus injections of arginine (arrows) administered under fasting and 230 mg/dL hyperglycemic clamp
conditions at day 75 and day 365 posttransplantation in the CIT07 protocol subjects. The gray shaded and hashed areas give
the 95% CIs for levels in the normal control group.