PKCδ Impaired Vessel Formation and Angiogenic Factor Expression in Diabetic Ischemic Limbs
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Blood flow reperfusion and recovery limb from ischemia. Laser Doppler imaging and reperfusion analysis of diabetic (DM) and
nondiabetic (NDM) Prkcd+/+ and Prkcd−/− mice. A and B: Morphological and observational analysis of necrosis and amputation of ischemic limbs after surgery. C: Results are shown as mean ± SD of 10–12 mice per group. *P = 0.0046 vs. NDM Prkcd+/+, †P = 0.0003 vs. DM Prkcd−/−.