Nutrient-Sensing Mechanisms in the Gut as Therapeutic Targets for Diabetes

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FIG. 3.
FIG. 3.

Gut nutrient-sensing mechanisms and bariatric surgery. Bariatric surgery bypasses the duodenum, and nutrient flow is enhanced into the jejunum, resulting in activation of jejunal nutrient-sensing mechanisms involving a series of biochemical reactions, gut-derived hormones, and neuronal circuitry to lower glucose production and plasma glucose levels.

This Article

  1. Diabetes vol. 62 no. 9 3005-3013