Protection of Islet Grafts Through Transforming Growth Factor-β–Induced Tolerogenic Dendritic Cells
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TGF-β–preconditioned BMDCs prolong islet graft survival. RIP-TNF NOD mice were confirmed to be diabetic and transplanted with
an islet graft mixed with 5 × 105 in vitro generated control BMDCs (●) or BMDCs incubated overnight with 5 ng/mL TGF-β (○). The difference between the groups
is depicted using a Kaplan-Meier plot, and the difference was determined using the log-rank test.