Protection of Islet Grafts Through Transforming Growth Factor-β–Induced Tolerogenic Dendritic Cells

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FIG. 7.
FIG. 7.

TGF-β–preconditioned BMDCs prolong islet graft survival. RIP-TNF NOD mice were confirmed to be diabetic and transplanted with an islet graft mixed with 5 × 105 in vitro generated control BMDCs (●) or BMDCs incubated overnight with 5 ng/mL TGF-β (○). The difference between the groups is depicted using a Kaplan-Meier plot, and the difference was determined using the log-rank test.

This Article

  1. Diabetes vol. 62 no. 9 3132-3142