Plasminogen Activator Inhibitor-1 Is Involved in Streptozotocin-Induced Bone Loss in Female Mice

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FIG. 6.
FIG. 6.

Effects of PAI-1 deficiency on adipogenesis in tibia of both sexes of diabetic mice. Levels of PPARγ mRNA (A) and aP2 mRNA (B) in control and streptozotocin-treated male PAI-1 WT and KO mice. Levels of PPARγ mRNA (C) and aP2 mRNA (D) in control and streptozotocin-treated female PAI-1 WT and KO mice. Data are expressed relative to β-actin mRNA values and are expressed as means ± SEM. *P < 0.05, **P < 0.01 (n = 5–7 in each group). Cont, control; STZ, streptozotocin.

This Article

  1. Diabetes vol. 62 no. 9 3170-3179