Irisin ERKs the Fat

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Figure 1
Figure 1

Recombinant irisin regulates the thermogenic program in fat through ERK and p38 pathways. Recombinant irisin produced in yeast is glycosylated and active. It induces the thermogenic gene program in 3T3-L1 cells and primary subcutaneous adipocytes. In vivo treatments of this recombinant protein in mice show strong anti-obesity effects and improve systematic glucose homeostasis.

This Article

  1. Diabetes vol. 63 no. 2 381-383
  1. Free via Open Access: OA