Response to Comment on Dutia et al. Limited Recovery of β-Cell Function After Gastric Bypass Despite Clinical Diabetes Remission. Diabetes 2014;63:1214−1223

  1. Blandine Laferrère1,2,6,7
  1. 1Department of Medicine, St. Luke’s Roosevelt Hospital Center, New York, NY
  2. 2New York Obesity Nutrition Research Center, St. Luke’s Roosevelt Hospital Center, New York, NY
  3. 3Department of Medicine, Albert Einstein School of Medicine, New York, NY
  4. 4Department of Medicine, Centre de Recherche Clinique Etienne-Le Bel, Université de Sherbrooke, Sherbrooke, Quebec, Canada
  5. 5Division of Minimally Invasive Surgery, Department of Surgery, St. Luke’s Roosevelt Hospital Center, New York, NY
  6. 6Columbia University College of Physicians and Surgeons, New York, NY
  7. 7Division of Endocrinology and Diabetes, St. Luke’s Roosevelt Hospital Center, New York, NY
  1. Corresponding author: Blandine Laferrère, bbl14{at}columbia.edu.

We thank Dr. Pontiroli, and agree with his commentary (1). Dr. Pontiroli provides an interesting observation regarding change in β-cell function following weight loss by gastric banding in subjects with type 2 diabetes. His data show minimal improvement in insulin release, as assessed by the Δinsulin/Δglucose during an oral glucose tolerance test (OGTT), but a significant improvement in insulin sensitivity by homeostasis model assessment, 18 months after gastric banding (1,2). In our study …

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  1. doi: 10.2337/db14-0112 Diabetes vol. 63 no. 4 e4
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