Diabetes: 67 (2)

February 01 2018; volume 67 issue 2

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In This Issue of Diabetes
Diabetes 2018 Feb; 67 (2): 167-168. https://doi.org/10.2337/db18-ti02

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Scientific Achievement Award Lecture

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Cellular Energy Sensing and Metabolism—Implications for Treating Diabetes: The 2017 Outstanding Scientific Achievement Award Lecture
Gregory R. Steinberg

Diabetes 2018 Feb; 67 (2): 169-179. https://doi.org/10.2337/dbi17-0039

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Commentary

Open Access
“NO” to Autophagy: Fat Does the Trick for Diabetes
Kezhong Zhang

Diabetes 2018 Feb; 67 (2): 180-181. https://doi.org/10.2337/dbi17-0048

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Technological Advances

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In Vivo Visualization of β-Cells by Targeting of GPR44
Olof Eriksson, Peter Johnström, Zsolt Cselenyi, Mahabuba Jahan, Ram K. Selvaraju, Marianne Jensen-Waern, Akihiro Takano, Maria Sörhede Winzell, Christer Halldin, Stanko Skrtic and Olle Korsgren

Diabetes 2018 Feb; 67 (2): 182-192. https://doi.org/10.2337/db17-0764

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Metabolism

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S-Nitrosoglutathione Reductase Dysfunction Contributes to Obesity-Associated Hepatic Insulin Resistance via Regulating Autophagy
Qingwen Qian, Zeyuan Zhang, Allyson Orwig, Songhai Chen, Wen-Xing Ding, Yanji Xu, Ryan C. Kunz, Nicholas R.L. Lind, Jonathan S. Stamler and Ling Yang

Diabetes 2018 Feb; 67 (2): 193-207. https://doi.org/10.2337/db17-0223

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Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling
Kevin C. Corbit, João Paulo G. Camporez, Lia R. Edmunds, Jennifer L. Tran, Nicholas B. Vera, Derek M. Erion, Rahul C. Deo, Rachel J. Perry, Gerald I. Shulman, Michael J. Jurczak and Ethan J. Weiss

Diabetes 2018 Feb; 67 (2): 208-221. https://doi.org/10.2337/db17-0524

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Regulation of Lipolytic Response and Energy Balance by Melanocortin 2 Receptor Accessory Protein (MRAP) in Adipocytes
Xiaodong Zhang, Alicia M. Saarinen, Latoya E. Campbell, Elena A. De Filippis and Jun Liu

Diabetes 2018 Feb; 67 (2): 222-234. https://doi.org/10.2337/db17-0862

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Obesity Studies

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Exosomes From Adipose-Derived Stem Cells Attenuate Adipose Inflammation and Obesity Through Polarizing M2 Macrophages and Beiging in White Adipose Tissue
Hui Zhao, Qianwen Shang, Zhenzhen Pan, Yang Bai, Zequn Li, Huiying Zhang, Qiu Zhang, Chun Guo, Lining Zhang and Qun Wang

Diabetes 2018 Feb; 67 (2): 235-247. https://doi.org/10.2337/db17-0356

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Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life
Mingyang Song, Yan Zheng, Lu Qi, Frank B. Hu, Andrew T. Chan and Edward L. Giovannucci

Diabetes 2018 Feb; 67 (2): 248-255. https://doi.org/10.2337/db17-1156

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Islet Studies

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miR-204 Controls Glucagon-Like Peptide 1 Receptor Expression and Agonist Function
SeongHo Jo, Junqin Chen, Guanlan Xu, Truman B. Grayson, Lance A. Thielen and Anath Shalev

Diabetes 2018 Feb; 67 (2): 256-264. https://doi.org/10.2337/db17-0506

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Clec16a, Nrdp1, and USP8 Form a Ubiquitin-Dependent Tripartite Complex That Regulates β-Cell Mitophagy
Gemma Pearson, Biaoxin Chai, Tracy Vozheiko, Xueying Liu, Malathi Kandarpa, Robert C. Piper and Scott A. Soleimanpour

Diabetes 2018 Feb; 67 (2): 265-277. https://doi.org/10.2337/db17-0321

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Glucocorticoids Reprogram β-Cell Signaling to Preserve Insulin Secretion
Nicholas H.F. Fine, Craig L. Doig, Yasir S. Elhassan, Nicholas C. Vierra, Piero Marchetti, Marco Bugliani, Rita Nano, Lorenzo Piemonti, Guy A. Rutter, David A. Jacobson, Gareth G. Lavery and David J. Hodson

Diabetes 2018 Feb; 67 (2): 278-290. https://doi.org/10.2337/db16-1356

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Complications

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Photobiomodulation Inhibits Long-term Structural and Functional Lesions of Diabetic Retinopathy
Yan Cheng, Yunpeng Du, Haitao Liu, Jie Tang, Alex Veenstra and Timothy S. Kern

Diabetes 2018 Feb; 67 (2): 291-298. https://doi.org/10.2337/db17-0803

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Pharmacology and Therapeutics

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Engineering Glucose Responsiveness Into Insulin
Niels C. Kaarsholm, Songnian Lin, Lin Yan, Theresa Kelly, Margaret van Heek, James Mu, Margaret Wu, Ge Dai, Yan Cui, Yonghua Zhu, Ester Carballo-Jane, Vijay Reddy, Peter Zafian, Pei Huo, Shuai Shi, Valentyn Antochshuk, Aimie Ogawa, Franklin Liu, Sandra C. Souza, Wolfgang Seghezzi, Joseph L. Duffy, Mark Erion, Ravi P. Nargund and David E. Kelley

Diabetes 2018 Feb; 67 (2): 299-308. https://doi.org/10.2337/db17-0577

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Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery
Daniel A. Briere, Ana B. Bueno, Ellen J. Gunn, M. Dodson Michael and Kyle W. Sloop

Diabetes 2018 Feb; 67 (2): 309-320. https://doi.org/10.2337/db17-0607

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The Synthetic Microneurotrophin BNN27 Affects Retinal Function in Rats With Streptozotocin-Induced Diabetes
Ruth Ibán-Arias, Silvia Lisa, Niki Mastrodimou, Despina Kokona, Emmanuil Koulakis, Panagiota Iordanidou, Antonis Kouvarakis, Myrto Fothiadaki, Sofia Papadogkonaki, Aggeliki Sotiriou, Haralambos E. Katerinopoulos, Achille Gravanis, Ioannis Charalampopoulos and Kyriaki Thermos

Diabetes 2018 Feb; 67 (2): 321-333. https://doi.org/10.2337/db17-0391

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Genetics/Genomes/Proteomics/Metabolomics

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A Partial Loss-of-Function Variant in AKT2 Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study
Aino Latva-Rasku, Miikka-Juhani Honka, Alena Stančáková, Heikki A. Koistinen, Johanna Kuusisto, Li Guan, Alisa K. Manning, Heather Stringham, Anna L. Gloyn, Cecilia M. Lindgren, T2D-GENES Consortium, Francis S. Collins, Karen L. Mohlke, Laura J. Scott, Tomi Karjalainen, Lauri Nummenmaa, Michael Boehnke, Pirjo Nuutila and Markku Laakso

Diabetes 2018 Feb; 67 (2): 334-342. https://doi.org/10.2337/db17-1142

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Erratum

Open Access
Erratum. Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition. Diabetes 2017;66:272–286
Kristina M. Mueller, Kerstin Hartmann, Doris Kaltenecker, Sabine Vettorazzi, Mandy Bauer, Lea Mauser, Sabine Amann, Sigrid Jall, Katrin Fischer, Harald Esterbauer, Timo D. Müller, Matthias H. Tschöp, Christoph Magnes, Johannes Haybaeck, Thomas Scherer, Natalie Bordag, Jan P. Tuckermann and Richard Moriggl

Diabetes 2018 Feb; 67 (2): 343-344. https://doi.org/10.2337/db18-er02a

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Expressions of Concern

Open Access
Expression of Concern. The IR₁₁₅₂ Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49:1194–1202. DOI: 10.2337/diabetes.49.7.1194. PMID: 10909978
Matilde Caruso, Claudia Miele, Andrea Oliva, Gerolama Condorelli, Francesco Oriente, Gabriele Riccardi, Brunella Capaldo, Francesca Fiory, Domenico Accili, Pietro Formisano and Francesco Beguinot

Diabetes 2018 Feb; 67 (2): 345. https://doi.org/10.2337/db17-ec2017a

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Open Access
Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50:1244–1252. DOI: 10.2337/diabetes.50.6.1244. PMID: 11375323
Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano and Francesco Beguinot

Diabetes 2018 Feb; 67 (2): 345-346. https://doi.org/10.2337/db17-ec2017b

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Open Access
Expression of Concern. Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase. Diabetes 2011;60:138–147. DOI: 10.2337/db10-0860. PMID: 20864515
Francesco Oriente, Salvatore Iovino, Serena Cabaro, Angela Cassese, Elena Longobardi, Claudia Miele, Paola Ungaro, Pietro Formisano, Francesco Blasi and Francesco Beguinot

Diabetes 2018 Feb; 67 (2): 346-347. https://doi.org/10.2337/db17-ec2017c

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Issues and Events

Open Access
Issues and Events
Diabetes 2018 Feb; 67 (2): 348. https://doi.org/10.2337/db18-ie02

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Table of Contents

In This Issue

Scientific Achievement Award Lecture

Commentary

Technological Advances

Metabolism

Obesity Studies

Islet Studies

Complications

Pharmacology and Therapeutics

Genetics/Genomes/Proteomics/Metabolomics

Erratum

Expressions of Concern

Issues and Events

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