Diabetes: 67 (5)

May 01 2018; volume 67 issue 5

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Open Access
In This Issue of Diabetes
Diabetes 2018 May; 67 (5): 783-784. https://doi.org/10.2337/db18-ti05

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ADA Award Lecture

Open Access
Metabolic Karma—The Atherogenic Legacy of Diabetes: The 2017 Edwin Bierman Award Lecture
Mark Emmanuel Cooper, Assam El-Osta, Terri Jean Allen, Anna Margareta Dorothea Watson, Merlin Christopher Thomas and Karin Agnes Maria Jandeleit-Dahm

Diabetes 2018 May; 67 (5): 785-790. https://doi.org/10.2337/dbi18-0010

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Metabolism

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Perilipin 3 Deficiency Stimulates Thermogenic Beige Adipocytes Through PPARα Activation
Yun Kyung Lee, Jee Hyung Sohn, Ji Seul Han, Yoon Jeong Park, Yong Geun Jeon, Yul Ji, Knut Tomas Dalen, Carole Sztalryd, Alan R. Kimmel and Jae Bum Kim

Diabetes 2018 May; 67 (5): 791-804. https://doi.org/10.2337/db17-0983

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Amylin Selectively Signals Onto POMC Neurons in the Arcuate Nucleus of the Hypothalamus
Thomas A. Lutz, Bernd Coester, Lynda Whiting, Ambrose A. Dunn-Meynell, Christina N. Boyle, Sebastien G. Bouret, Barry E. Levin and Christelle Le Foll

Diabetes 2018 May; 67 (5): 805-817. https://doi.org/10.2337/db17-1347

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Hepatic F-Box Protein FBXW7 Maintains Glucose Homeostasis Through Degradation of Fetuin-A
Jiejie Zhao, Xuelian Xiong, Yao Li, Xing Liu, Tao Wang, Hong Zhang, Yang Jiao, Jingjing Jiang, Huijie Zhang, Qiqun Tang, Xin Gao, Xuejun Li, Yan Lu, Bin Liu, Cheng Hu and Xiaoying Li

Diabetes 2018 May; 67 (5): 818-830. https://doi.org/10.2337/db17-1348

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Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise
Daniel S. Lark, Jamie R. Kwan, P. Mason McClatchey, Merrygay N. James, Freyja D. James, John R.B. Lighton, Louise Lantier and David H. Wasserman

Diabetes 2018 May; 67 (5): 831-840. https://doi.org/10.2337/db17-1293

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Catestatin Inhibits Obesity-Induced Macrophage Infiltration and Inflammation in the Liver and Suppresses Hepatic Glucose Production, Leading to Improved Insulin Sensitivity
Wei Ying, Sumana Mahata, Gautam K. Bandyopadhyay, Zhenqi Zhou, Joshua Wollam, Jessica Vu, Rafael Mayoral, Nai-Wen Chi, Nicholas J.G. Webster, Angelo Corti and Sushil K. Mahata

Diabetes 2018 May; 67 (5): 841-848. https://doi.org/10.2337/db17-0788

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Signal Transduction

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Regulation of K_ATP Channel Trafficking in Pancreatic β-Cells by Protein Histidine Phosphorylation
Shekhar Srivastava, Zhai Li, Irfana Soomro, Ying Sun, Jianhui Wang, Li Bao, William A. Coetzee, Charles A. Stanley, Chonghong Li and Edward Y. Skolnik

Diabetes 2018 May; 67 (5): 849-860. https://doi.org/10.2337/db17-1433

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Obesity Studies

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HLA-B*07, HLA-DRB1*07, HLA-DRB1*12, and HLA-C*03:02 Strongly Associate With BMI: Data From 1.3 Million Healthy Chinese Adults
Jie Shen, Tingwei Guo, Tao Wang, Yisong Zhen, Xiao Ma, Yuan Wang, Zhi-Xin Zhang, Jian-Ping Cai, Wei Mao, Fa-Ming Zhu, Jian-Ping Li, Zhen-Lei Wang, De-Mei Zhang, Meng-Li Liu, Xiao-Yan Shan, Bo-Wei Zhang, Chuan-Fu Zhu, Zhi-Hui Deng, Wei-Jian Yu, Qiang Chen, Guo-Liang Li, Tao Yang, Shan Lu, Qin-Qin Pan, Su Fan, Xiao-Yan Wang, Xing Zhao, Xin-Yun Bi, Yan-Hui Qiao, Pin-Can Su, Rong Lv, Guo-Ying Li, Heng-Cong Li, Bin Pei, Li-Xin Jiao, Gang Shen, Jie Liu, Zhi-Hui Feng, Yu-Ping Su, Yu-Bin Xie, Wen-Ying Di, Xin-Yu Wang, Xiang Liu, Xiao-Ping Zhang, Dan Du, Qi Liu, Ying Han, Jia-Wei Chen, Min Gu and Leslie J. Baier, on behalf of the China Marrow Donor Program

Diabetes 2018 May; 67 (5): 861-871. https://doi.org/10.2337/db17-0852

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Islet Studies

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CDKN2A/B T2D Genome-Wide Association Study Risk SNPs Impact Locus Gene Expression and Proliferation in Human Islets
Yahui Kong, Rohit B. Sharma, Socheata Ly, Rachel E. Stamateris, William M. Jesdale and Laura C. Alonso

Diabetes 2018 May; 67 (5): 872-884. https://doi.org/10.2337/db17-1055

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Elevated Medium-Chain Acylcarnitines Are Associated With Gestational Diabetes Mellitus and Early Progression to Type 2 Diabetes and Induce Pancreatic β-Cell Dysfunction
Battsetseg Batchuluun, Dana Al Rijjal, Kacey J. Prentice, Judith A. Eversley, Elena Burdett, Haneesha Mohan, Alpana Bhattacharjee, Erica P. Gunderson, Ying Liu and Michael B. Wheeler

Diabetes 2018 May; 67 (5): 885-897. https://doi.org/10.2337/db17-1150

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Role of Protein Phosphatase 1 and Inhibitor of Protein Phosphatase 1 in Nitric Oxide–Dependent Inhibition of the DNA Damage Response in Pancreatic β-Cells
Bryndon J. Oleson, Aaron Naatz, Sarah C. Proudfoot, Chay Teng Yeo and John A. Corbett

Diabetes 2018 May; 67 (5): 898-910. https://doi.org/10.2337/db17-1062

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Postnatal Ontogenesis of the Islet Circadian Clock Plays a Contributory Role in β-Cell Maturation Process
Kuntol Rakshit, Jingyi Qian, Krutika Satish Gaonkar, Sangeeta Dhawan, Christopher S. Colwell and Aleksey V. Matveyenko

Diabetes 2018 May; 67 (5): 911-922. https://doi.org/10.2337/db17-0850

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Immunology and Transplantation

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Improved Murine MHC-Deficient HLA Transgenic NOD Mouse Models for Type 1 Diabetes Therapy Development
Jeremy J. Racine, Isabel Stewart, Jeremy Ratiu, Greg Christianson, Emily Lowell, Kelsay Helm, Jennifer Allocco, Richard S. Maser, Yi-Guang Chen, Cathleen M. Lutz, Derry Roopenian, Jennifer Schloss, Teresa P. DiLorenzo and David V. Serreze

Diabetes 2018 May; 67 (5): 923-935. https://doi.org/10.2337/db17-1467

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Detection and Characterization of CD8⁺ Autoreactive Memory Stem T Cells in Patients With Type 1 Diabetes
Debora Vignali, Elisa Cantarelli, Carlotta Bordignon, Adriana Canu, Antonio Citro, Andrea Annoni, Lorenzo Piemonti and Paolo Monti

Diabetes 2018 May; 67 (5): 936-945. https://doi.org/10.2337/db17-1390

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Complications

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A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome
Jenny E. Kanter, Farah Kramer, Shelley Barnhart, Jeffrey M. Duggan, Masami Shimizu-Albergine, Vishal Kothari, Alan Chait, Stephan D. Bouman, Jessica A. Hamerman, Bo F. Hansen, Grith S. Olsen and Karin E. Bornfeldt

Diabetes 2018 May; 67 (5): 946-959. https://doi.org/10.2337/db17-0744

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RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis
Shinji Hagiwara, Karly Sourris, Mark Ziemann, Wu Tieqiao, Muthukumar Mohan, Aaron D. McClelland, Eoin Brennan, Josephine Forbes, Melinda Coughlan, Brooke Harcourt, Sally Penfold, Bo Wang, Gavin Higgins, Raelene Pickering, Assam El-Osta, Merlin C. Thomas, Mark E. Cooper and Phillip Kantharidis

Diabetes 2018 May; 67 (5): 960-973. https://doi.org/10.2337/db17-0538

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Fibroblast Growth Factor 21 Protects Photoreceptor Function in Type 1 Diabetic Mice
Zhongjie Fu, Zhongxiao Wang, Chi-Hsiu Liu, Yan Gong, Bertan Cakir, Raffael Liegl, Ye Sun, Steven S. Meng, Samuel B. Burnim, Ivana Arellano, Elizabeth Moran, Rubi Duran, Alexander Poblete, Steve S. Cho, Saswata Talukdar, James D. Akula, Ann Hellström and Lois E.H. Smith

Diabetes 2018 May; 67 (5): 974-985. https://doi.org/10.2337/db17-0830

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Urinary IgG4 and Smad1 Are Specific Biomarkers for Renal Structural and Functional Changes in Early Stages of Diabetic Nephropathy
Toshio Doi, Tatsumi Moriya, Yui Fujita, Naoto Minagawa, Masaru Usami, Tomoko Sasaki, Hideharu Abe, Seiji Kishi, Taichi Murakami, Motoshi Ouchi, Go Ichien, Keiichi Yamamoto, Hiroki Ikeda, Yasuhiko Koezuka, Norimichi Takamatsu, Kenji Shima, Michael Mauer, Kojiro Nagai and Tatsuya Tominaga

Diabetes 2018 May; 67 (5): 986-993. https://doi.org/10.2337/db17-1043

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Altered Odor-Induced Brain Activity as an Early Manifestation of Cognitive Decline in Patients With Type 2 Diabetes
Zhou Zhang, Bing Zhang, Xin Wang, Xin Zhang, Qing X. Yang, Zhao Qing, Jiaming Lu, Yan Bi and Dalong Zhu

Diabetes 2018 May; 67 (5): 994-1006. https://doi.org/10.2337/db17-1274

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Metabolic Syndrome Is Associated With Impaired Diastolic Function Independently of MRI-Derived Myocardial Extracellular Volume: The MESA Study
Ricardo Ladeiras-Lopes, Henrique T. Moreira, Nuno Bettencourt, Ricardo Fontes-Carvalho, Francisco Sampaio, Bharath Ambale-Venkatesh, Colin Wu, Kiang Liu, Alain G. Bertoni, Pamela Ouyang, David A. Bluemke and João A. Lima

Diabetes 2018 May; 67 (5): 1007-1012. https://doi.org/10.2337/db17-1496

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Genetics/Genomes/Proteomics/Metabolomics

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Circulating miRNA Profiles Associated With Hyperglycemia in Patients With Type 1 Diabetes
Eiichiro Satake, Marcus G. Pezzolesi, Zaipul I. Md Dom, Adam M. Smiles, Monika A. Niewczas and Andrzej S. Krolewski

Diabetes 2018 May; 67 (5): 1013-1023. https://doi.org/10.2337/db17-1207

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Fetal Genotype and Maternal Glucose Have Independent and Additive Effects on Birth Weight
Alice E. Hughes, Michael Nodzenski, Robin N. Beaumont, Octavious Talbot, Beverley M. Shields, Denise M. Scholtens, Bridget A. Knight, William L. Lowe, Jr., Andrew T. Hattersley and Rachel M. Freathy

Diabetes 2018 May; 67 (5): 1024-1029. https://doi.org/10.2337/db17-1188

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Erratum

Open Access
Erratum. Engineering Glucose Responsiveness Into Insulin. Diabetes 2018;67:299–308
Niels C. Kaarsholm, Songnian Lin, Lin Yan, Theresa Kelly, Margaret van Heek, James Mu, Margaret Wu, Ge Dai, Yan Cui, Yonghua Zhu, Ester Carballo-Jane, Vijay Reddy, Peter Zafian, Pei Huo, Shuai Shi, Valentyn Antochshuk, Aimie Ogawa, Franklin Liu, Sandra C. Souza, Wolfgang Seghezzi, Joseph L. Duffy, Mark Erion, Ravi P. Nargund and David E. Kelley

Diabetes 2018 May; 67 (5): 1030. https://doi.org/10.2337/db18-er05a

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Issues and Events

Open Access
Issues and Events
Diabetes 2018 May; 67 (5): 1031. https://doi.org/10.2337/db18-ie05

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Table of Contents

In This Issue

ADA Award Lecture

Metabolism

Signal Transduction

Obesity Studies

Islet Studies

Immunology and Transplantation

Complications

Genetics/Genomes/Proteomics/Metabolomics

Erratum

Issues and Events

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