Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons
- Received September 10, 2016.
- Accepted March 8, 2017.
- Published March 14, 2017.
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© 2017 by the American Diabetes Association. http://www.diabetesjournals.org/content/licenseReaders may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.
- Luis Varela1⇑,
- Shigetomo Suyama1,
- Yan Huang2,
- Marya Shanabrough1,
- Matthias H. Tschoep3,
- Xiao-Bing Gao1,
- Frank J. Giordano2 and
- Tamas L. Horvath1,3⇑
- 1Program in Integrative Cell Signaling and Neurobiology of Metabolism, Section of Comparative Medicine, and
- 2Department of Medicine ,Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT 06520, USA;
- 3Helmholtz Diabetes Center, Helmholtz Zentrum München& Division of Metabolic Diseases, Technische Universität München, 85764 Neuherberg, Germany.
- Corresponding Authors: Luis Varela, Email: and Tamas L. Horvath, Email: