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Original Research:
• Lili Guo,
• Akari Inada,
• Cristina Aguayo-Mazzucato,
• Jennifer Hollister-Lock,
• Yoshio Fujitani,
• Gordon C. Weir,
• Christopher VE Wright,
• Arun Sharma,
• and Susan Bonner-Weir
PDX1 in ducts is not required for postnatal formation of β-cells but is necessary for their subsequent maturation Diabetes published ahead of print June 17, 2013, doi:10.2337/db12-1833
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Original Research:
• Junjie Yu,
• Fei Xiao,
• Qian Zhang,
• Bin Liu,
• Yajie Guo,
• Ziquan Lv,
• Tingting Xia,
• Shanghai Chen,
• Kai Li,
• Ying Du,
• and Feifan Guo
Prolactin Receptor (PRLR) regulates hepatic insulin sensitivity in mice via Signal Transducer and Activator of Transcription (STAT)5 Diabetes published ahead of print June 17, 2013, doi:10.2337/db13-0182
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Original Research:
• Don-Kyu Kim,
• Gil-Tae Gang,
• Dongryeol Ryu,
• Minseob Koh,
• Yo-Na Kim,
• Su Sung Kim,
• Jinyoung Park,
• Yong-Hoon Kim,
• Taebo Sim,
• In-Kyu Lee,
• Cheol Soo Choi,
• Seung Bum Park,
• Chul-Ho Lee,
• Seung-Hoi Koo,
• and Hueng-Sik Choi
Inverse agonist of nuclear receptor ERRγ mediates anti-diabetic effect through inhibition of hepatic gluconeogenesis Diabetes published ahead of print June 17, 2013, doi:10.2337/db12-0946
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Original Research:
• Jingyi Qian,
• Gene D. Block,
• Christopher S. Colwell,
• and Aleksey V. Matveyenko
Consequences of exposure to light at night on the pancreatic islet circadian clock and function in rats Diabetes published ahead of print June 17, 2013, doi:10.2337/db12-1543
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Original Research:
• Kirk M. Habegger,
• Henriette Kirchner,
• Chun-Xia Yi,
• Kristy M. Heppner,
• Dan Sweeney,
• Nickki Ottaway,
• Jenna Holland,
• Sarah Amburgy,
• Christine Raver,
• Radhakrishna Krishna,
• Timo D. Müller,
• Diego Perez-Tilve,
• Paul T. Pfluger,
• Silvana Obici,
• Richard D DiMarchi,
• David A. D’Alessio,
• Randy J. Seeley,
• and Matthias H. Tschöp
GLP-1R Agonism Enhances Adjustable Gastric Banding In Diet-Induced Obese Rats Diabetes published ahead of print June 17, 2013, doi:10.2337/db13-0117
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Original Research:
• Richard L Young,
• Bridgette Chia,
• Nicole J Isaacs,
• Jing Ma,
• Joan Khoo,
• Tongzhi Wu,
• Michael Horowitz,
• and Christopher K Rayner
Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes Diabetes published ahead of print June 12, 2013, doi:10.2337/db13-0581
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Original Research:
• Hans P.M.M. Lauritzen,
• Josef Brandauer,
• Peter Schjerling,
• Ho-Jin Koh,
• Henrik Galbo,
• Michael F. Hirshman,
• Jonas T. Treebak,
• and Laurie J. Goodyear
Contraction and AICAR Stimulate IL-6 Vesicle Depletion from Skeletal Muscle Fibers in vivo Diabetes published ahead of print June 12, 2013, doi:10.2337/db12-1261
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Original Research:
• Orchard TJ,
• Sun W,
• Cleary P,
• Genuth S,
• Lachin JM,
• McGee P,
• Paterson AD,
• Raskin P,
• Anbinder Y,
• Levy AP,
• and and the DCCT/EDIC Research Group
Haptoglobin Genotype and the Rate of Renal Function Decline in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Diabetes published ahead of print June 12, 2013, doi:10.2337/db13-0256
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Original Research:
• Yunxia Zhu,
• Weiyan You,
• Hongdong Wang,
• Yating Li,
• Nan Qiao,
• Yuguang Shi,
• Chenyu Zhang,
• David Bleich,
• and Xiao Han
MicroRNA-24/MODY Gene Regulatory Pathway Mediates Pancreatic Beta-Cell Dysfunction Diabetes published ahead of print June 12, 2013, doi:10.2337/db13-0151
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Original Research:
• Christopher Lipina,
• Katherine Macrae,
• Tamara Suhm,
• Cora Weigert,
• Agnieszka Blachnio-Zabielska,
• Marcin Baranowski,
• Jan Gorski,
• Karl Burgess,
• and Harinder S Hundal
Mitochondrial Substrate Availability and its Role in Lipid-Induced Insulin Resistance and Proinflammatory Signalling in Skeletal Muscle Diabetes published ahead of print June 3, 2013, doi:10.2337/db13-0264
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Original Research:
• Erica Rurali,
• Marina Noris,
• Antonietta Chianca,
• Roberta Donadelli,
• Federica Banterla,
• Miriam Galbusera,
• Giulia Gherardi,
• Sara Gastoldi,
• Aneliya Parvanova Ilieva,
• Ilian Petrov Iliev,
• Antonio Bossi,
• Carolina Haefliger,
• Roberto Trevisan,
• Giuseppe Remuzzi,
• Piero Ruggenenti,
• and for the BENEDICT Study Group (See Online Supplemental Material)
ADAMTS13 Predicts Renal and Cardiovascular Events in Type 2 Diabetics and Response to Therapy Diabetes published ahead of print June 3, 2013, doi:10.2337/db13-0530
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Original Research:
• Mariana Lazo,
• J. Hunter Young,
• Frederick L. Brancati,
• Josef Coresh,
• Seamus Whelton,
• Chiadi E. Ndumele,
• Ron Hoogeveen,
• Christie M. Ballantyne,
• and Elizabeth Selvin
N-terminal pro-Brain Natriuretic Peptide and Risk of Diabetes Diabetes published ahead of print June 3, 2013, doi:10.2337/db13-0478
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Original Research:
• Tobias Duennwald,
• Luciano Bernardi,
• Daniel Gordin,
• Anna Sandelin,
• Anna Syreeni,
• Christopher Fogarty,
• Janne P. Kytö,
• Hannes Gatterer,
• Markku Lehto,
• Sohvi Hörkkö,
• Carol Forsblom,
• Martin Burtscher,
• Per-Henrik Groop,
• and on behalf of the FinnDiane Study Group
Effects of a Single Bout of Interval Hypoxia on Cardio-Respiratory Control in Patients with Type 1 Diabetes Mellitus Diabetes published ahead of print June 3, 2013, doi:10.2337/db13-0167
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Original Research:
• Paola Maffi,
• Gianpaolo Balzano,
• Maurilio Ponzoni,
• Rita Nano,
• Valeria Sordi,
• Raffaella Melzi,
• Alessia Mercalli,
• Marina Scavini,
• Antonio Esposito,
• Jacopo Peccatori,
• Elisa Cantarelli,
• Carlo Messina,
• Massimo Bernardi,
• Alessandro Del Maschio,
• Carlo Staudacher,
• Claudio Doglioni,
• Fabio Ciceri,
• Antonio Secchi,
• and Lorenzo Piemonti
Autologous Pancreatic Islet Transplantation in Human Bone Marrow Diabetes published ahead of print June 3, 2013, doi:10.2337/db13-0465
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Original Research:
• Emily K. Anderson,
• Dario A. Gutierrez,
• Arion Kennedy,
• and Alyssa H. Hasty
Weight Cycling Increases T Cell Accumulation in Adipose Tissue and Impairs Systemic Glucose Tolerance Diabetes published ahead of print June 3, 2013, doi:10.2337/db12-1076
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Original Research:
• T. David C Thomas,
• F. Susan Wong,
• Paola Zaccone,
• E. Allison Green,
• and Maja Wallberg
Protection of islet grafts through TGF beta induced tolerogenic DC Diabetes published ahead of print May 28, 2013, doi:10.2337/db12-1740
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Original Research:
• Xiaoxiao Wan,
• F. Betul Guloglu,
• Amie M. VanMorlan,
• Linda M. Rowland,
• Sarah Zaghouani,
• Jason A. Cascio,
• Mermagya Dhakal,
• Christine M. Hoeman,
• and Habib Zaghouani
Recovery from Overt Type 1 Diabetes Ensues When Immune Tolerance and β Cell Formation Are Coupled with Regeneration of Endothelial Cells in the Pancreatic Islets Diabetes published ahead of print May 28, 2013, doi:10.2337/db12-1281
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Original Research:
• Yukinori Tamura,
• Naoyuki Kawao,
• Kiyotaka Okada,
• Masato Yano,
• Katsumi Okumoto,
• Osamu Matsuo,
• and Hiroshi Kaji
Plasminogen activator inhibitor-1 is involved in streptozotocin-induced bone loss in female mice Diabetes published ahead of print May 28, 2013, doi:10.2337/db12-1552
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Original Research:
• Henk M. De Feyter,
• Graeme F. Mason,
• Gerald I. Shulman,
• Douglas L. Rothman,
• and Kitt Falk Petersen
Increased Brain Lactate Concentrations without Increased Lactate Oxidation during Hypoglycemia in Type 1 Diabetic Individuals Diabetes published ahead of print May 28, 2013, doi:10.2337/db13-0313
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Original Research:
• Leen M. ‘t Hart,
• Andreas Fritsche,
• Giel Nijpels,
• Nienke van Leeuwen,
• Louise A. Donnelly,
• Jacqueline M. Dekker,
• Marjan Alssema,
• Joao Fadista,
• Françoise Carlotti,
• Anette P. Gjesing,
• Colin N.A. Palmer,
• Timon W. van Haeften,
• Silke A. Herzberg-Schäfer,
• Annemarie M.C. Simonis-Bik,
• Jeanine J. Houwing-Duistermaat,
• Quinta Helmer,
• Joris Deelen,
• Bruno Guigas,
• Torben Hansen,
• Fausto Machicao,
• Gonneke Willemsen,
• Robert J. Heine,
• Mark H.H. Kramer,
• Jens J. Holst,
• Eelco J.P. de Koning,
• Hans-Ulrich Häring,
• Oluf Pedersen,
• Leif Groop,
• Eco J.C. de Geus,
• P. Eline Slagboom,
• Dorret I. Boomsma,
• Elisabeth M.W. Eekhoff,
• Ewan R Pearson,
• and Michaela Diamant
The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway Diabetes published ahead of print May 14, 2013, doi:10.2337/db13-0227
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Original Research:
• Léonie Egli,
• Virgile Lecoultre,
• Fanny Theytaz,
• Vanessa Campos,
• Leanne Hodson,
• Philippe Schneiter,
• Bettina Mittendorfer,
• Bruce W. Patterson,
• Barbara A. Fielding,
• Philipp A. Gerber,
• Vittorio Giusti,
• Kaspar Berneis,
• and Luc Tappy
Exercise Prevents Fructose-Induced Hypertriglyceridemia in Healthy Young Subjects Diabetes published ahead of print May 14, 2013, doi:10.2337/db12-1651
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Original Research:
• Birgitte Lindegaard,
• Vance B. Matthews,
• Claus Brandt,
• Pernille Hojman,
• Tamara L. Allen,
• Emma Estevez,
• Matthew J. Watt,
• Clinton R. Bruce,
• Ole Mortensen,
• Susanne Syberg,
• Caroline Rudnicka,
• Julie Abildgaard,
• Henriette Pilegaard,
• Juan Hidalgo,
• Susanne Ditlevsen,
• Thomas J. Alsted,
• Andreas N. Madsen,
• Bente K. Pedersen,
• and Mark A. Febbraio
Interleukin-18 activates skeletal muscle AMPK and reduces weight gain and insulin resistance in mice Diabetes published ahead of print May 13, 2013, doi:10.2337/db12-1095
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Original Research:
• Rica Tanaka,
• Max Vaynrub,
• Haruchika Masuda,
• Rie Ito,
• Michiru Kobori,
• Muneo Miyasaka,
• Hiroshi Mizuno,
• Stephen M. Warren,
• and Takayuki Asahara
Quality Control Culture System Restores Diabetic Endothelial Progenitor Cell Vasculogenesis and Accelerates Wound Closure Diabetes published ahead of print May 13, 2013, doi:10.2337/db12-1621
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Original Research:
• Scott M. Blackman,
• Clayton W. Commander,
• Christopher Watson,
• Kristin M. Arcara,
• Lisa J. Strug,
• Jaclyn R. Stonebraker,
• Fred A. Wright,
• Johanna M. Rommens,
• Lei Sun,
• Rhonda G. Pace,
• Sarah A. Norris,
• Peter R. Durie,
• Mitchell L. Drumm,
• Michael R. Knowles,
• and Garry R. Cutting
Genetic modifiers of cystic fibrosis-related diabetes Diabetes published ahead of print May 13, 2013, doi:10.2337/db13-0510
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Original Research:
• Nurit Hadad,
• Olga Burgazliev,
• Vered Elgazar-Carmon,
• Yulia Solomonov,
• Stephan Wueest,
• Flurin Item,
• Daniel Konrad,
• Assaf Rudich,
• and Rachel Levy
Induction of cytosolic phospholipase A₂α is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high fat feeding Diabetes published ahead of print May 13, 2013, doi:10.2337/db12-1300
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Original Research:
• Audrey Baeyens,
• Louis Pérol,
• Gwladys Fourcade,
• Nicolas Cagnard,
• Wassila Carpentier,
• Janine Woytschak,
• Onur Boyman,
• Agnès Hartemann,
• and Eliane Piaggio
Limitations of IL-2 and rapamycin in immunotherapy of type 1 diabetes Diabetes published ahead of print May 13, 2013, doi:10.2337/db13-0214
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Original Research:
• Brigitte I Frohnert,
• David R Jacobs, Jr.,
• Julia Steinberger,
• Antoinette Moran,
• Lyn M Steffen,
• and Alan R Sinaiko
Relation between Serum Free Fatty Acids and Adiposity, Insulin Resistance and Cardiovascular Risk Factors from Adolescence to Adulthood Diabetes published ahead of print May 13, 2013, doi:10.2337/db12-1122
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Original Research:
• Paul V. Sabatini,
• Nicole A.J. Krentz,
• Bader Zarrouki,
• Clara Y. Westwell-Roper,
• Cuilan Nian,
• Ryan A. Uy,
• A.M. James Shapiro,
• Vincent Poitout,
• and Francis C. Lynn
Npas4 Is a Novel Activity-Regulated Cytoprotective Factor in Pancreatic β-Cells Diabetes published ahead of print May 8, 2013, doi:10.2337/db12-1527
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Original Research:
• Heather C. Denroche,
• Whitney L. Quong,
• Jennifer E. Bruin,
• Eva Tudurí,
• Ali Asadi,
• Maria M. Glavas,
• Jessica K. Fox,
• and Timothy J. Kieffer
Leptin administration enhances islet transplant performance in diabetic mice Diabetes published ahead of print May 8, 2013, doi:10.2337/db12-1684
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Original Research:
• Chunling Huang,
• Sylvie Shen,
• Qing Ma,
• Jason Chen,
• Anthony Gill,
• Carol A. Pollock,
• and Xin-Ming Chen
Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice Diabetes published ahead of print May 8, 2013, doi:10.2337/db13-0135
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Original Research:
• Abulizi Abudukadier,
• Yoshihito Fujita,
• Akio Obara,
• Akiko Ohashi,
• Toru Fukushima,
• Yuichi Sato,
• Masahito Ogura,
• Yasuhiko Nakamura,
• Shimpei Fujimoto,
• Masaya Hosokawa,
• Hiroyuki Hasegawa,
• and Nobuya Inagaki
Tetrahydrobiopterin has a glucose-lowering effect by suppressing hepatic gluconeogenesis in an endothelial nitric oxide synthase-dependent manner in diabetic mice Diabetes published ahead of print May 6, 2013, doi:10.2337/db12-1242
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Original Research:
• Nils B Jørgensen,
• Carsten Dirksen,
• Kirstine N Bojsen-møller,
• Siv H Jacobsen,
• Dorte Worm,
• Dorte L Hansen,
• Viggo B Kristiansen,
• Lars Naver,
• Sten Madsbad,
• and Jens J Holst
The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes Diabetes published ahead of print May 6, 2013, doi:10.2337/db13-0022
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Original Research:
• Supriya D. Deshpande,
• Sumanth Putta,
• Mei Wang,
• Jennifer Y. Lai,
• Markus Bitzer,
• Robert G. Nelson,
• Linda L. Lanting,
• Mitsuo Kato,
• and Rama Natarajan
Transforming Growth Factor-β induced cross talk between p53 and a microRNA in the pathogenesis of Diabetic Nephropathy Diabetes published ahead of print May 6, 2013, doi:10.2337/db13-0305
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Original Research:
• Kim S. Bell-Anderson,
• Alister P. Funnell,
• Helen Williams,
• Hanapi Mat Jusoh,
• Tiffany Scully,
• Wooi F. Lim,
• Jon G. Burdach,
• Ka Sin Mak,
• Alexander J. Knights,
• Andrew J. Hoy,
• Hannah R. Nicholas,
• Amanda Sainsbury,
• Nigel Turner,
• Richard C. Pearson,
• and Merlin Crossley
Loss of Krüppel-like Factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2). Diabetes published ahead of print April 30, 2013, doi:10.2337/db12-1745
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Original Research:
• Robert L Hanson,
• Tingwei Guo,
• Yunhua Li Muller,
• Jamie Fleming,
• William C Knowler,
• Sayuko Kobes,
• Clifton Bogardus,
• and Leslie J Baier
Strong Parent-of-Origin Effects in the Association of KCNQ1 Variants with Type 2 Diabetes Mellitus in American Indians Diabetes published ahead of print April 29, 2013, doi:10.2337/db12-1767
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Original Research:
• Chunhua Dai,
• Marcela Brissova,
• Rachel B. Reinert,
• Lara Nyman,
• Eric H. Liu,
• Courtney Thompson,
• Alena Shostak,
• Masakazu Shiota,
• Takamune Takahashi,
• and Alvin C. Powers
Pancreatic Islet Vasculature Adapts to Insulin Resistance through Dilation and Not Angiogenesis Diabetes published ahead of print April 29, 2013, doi:10.2337/db12-1657
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Original Research:
• Rachel E. Jennings,
• Andrew A. Berry,
• Rebecca Kirkwood-Wilson,
• Neil A. Roberts,
• Thomas Hearn,
• Rachel J. Salisbury,
• Jennifer Blaylock,
• Karen Piper Hanley,
• and Neil A. Hanley
Development of the human pancreas from foregut to endocrine commitment Diabetes published ahead of print April 29, 2013, doi:10.2337/db12-1479
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Original Research:
• Yusuke Kaida,
• Kei Fukami,
• Takanori Matsui,
• Yuichiro Higashimoto,
• Yuri Nishino,
• Nana Obara,
• Yosuke Nakayama,
• Ryotaro Ando,
• Maki Toyonaga,
• Seiji Ueda,
• Masayoshi Takeuchi,
• Hiroyoshi Inoue,
• Seiya Okuda,
• and Sho-ichi Yamagishi
DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy Diabetes published ahead of print April 29, 2013, doi:10.2337/db12-1608
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Original Research:
• Matej Orešič,
• Peddinti Gopalacharyulu,
• Juha Mykkänen,
• Niina Lietzen,
• Marjaana Mäkinen,
• Heli Nygren,
• Satu Simell,
• Ville Simell,
• Heikki Hyöty,
• Riitta Veijola,
• Jorma Ilonen,
• Marko Sysi-Aho,
• Mikael Knip,
• Tuulia Hyötyläinen,
• and Olli Simell
Cord Serum Lipidome in Prediction of Islet Autoimmunity and Type 1 Diabetes Diabetes published ahead of print April 29, 2013, doi:10.2337/db13-0159
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Original Research:
• Seth J. Salpeter,
• Abed Khalaileh,
• Noa Weinberg-Corem,
• Oren Ziv,
• Ben Glaser,
• and Yuval Dor
Systemic regulation of the age-related decline of pancreatic beta-cell replication Diabetes published ahead of print April 29, 2013, doi:10.2337/db13-0160
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Original Research:
• Negar Karimian,
• Tairan Qin,
• Tao Liang,
• Mayowa Osundiji,
• Yachi Huang,
• Trevor Teich,
• Michael C. Riddell,
• Mark S. Cattral,
• David H. Coy,
• Mladen Vranic,
• and Herbert Y. Gaisano
Somatostatin Receptor Type 2 Antagonism Improves Glucagon Counter-regulation In BioBreeding Diabetic Rats Diabetes published ahead of print April 29, 2013, doi:10.2337/db13-0164
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Original Research:
• Michael R. Rickels,
• Chengyang Liu,
• Richard D. Shlansky-Goldberg,
• Scott A. Soleimanpour,
• Kumar Vivek,
• Malek Kamoun,
• Zaw Min,
• Eileen Markmann,
• Maral Palangian,
• Cornelia Dalton-Bakes,
• Carissa Fuller,
• Allen J. Chiou,
• Clyde F. Barker,
• Eline T. Luning Prak,
• and Ali Naji
Improvement in β-Cell Secretory Capacity Following Human Islet Transplantation According to the CIT07 Protocol Diabetes published ahead of print April 29, 2013, doi:10.2337/db12-1802
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Original Research:
• Sarah J. Lessard,
• Donato A. Rivas,
• Ana B. Alves-Wagner,
• Michael F. Hirshman,
• Iain J. Gallagher,
• Dumitru Constantin-Teodosiu,
• Ryan Atkins,
• Paul Greenhaff,
• Nathan R. Qi,
• Thomas Gustafsson,
• Roger A. Fielding,
• James A. Timmons,
• Steven L. Britton,
• Lauren G. Koch,
• and Laurie J. Goodyear
Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks Diabetes published ahead of print April 22, 2013, doi:10.2337/db13-0062
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Original Research:
• Faidon Magkos,
• David Bradley,
• George G. Schweitzer,
• Brian N. Finck,
• J. Christopher Eagon,
• Olga Ilkayeva,
• Christopher B. Newgard,
• and Samuel Klein
Effect of roux-en-Y gastric bypass and laparoscopic adjustable gastric banding on branched-chain amino acid metabolism Diabetes published ahead of print April 22, 2013, doi:10.2337/db13-0185
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Original Research:
• Clifton Jackness,
• Wahida Karmally,
• Gerardo Febres,
• Irene M. Conwell,
• Leaque Ahmed,
• Marc Bessler,
• Donald J. McMahon,
• and Judith Korner
Very Low Calorie Diet Mimics the Early Beneficial Effect of Roux-en-Y Gastric Bypass on Insulin Sensitivity and Beta-Cell Function in Type 2 Diabetic Patients Diabetes published ahead of print April 22, 2013, doi:10.2337/db12-1762
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Original Research:
• Magdalena A. Mazur,
• Marcus Winkler,
• Elvira Ganić,
• Jesper K. Colberg,
• Jenny Johansson,
• Hedvig Bennet,
• Malin Fex,
• Ulrike A. Nuber,
• and Isabella Artner
Microphtalmia transcription factor (Mitf) regulates pancreatic β cell function Diabetes published ahead of print April 22, 2013, doi:10.2337/db12-1464
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Original Research:
• Woo-Jin Song,
• Prosenjit Mondal,
• Yuanyuan Li,
• Suh Eun Lee,
• and Mehboob A. Hussain
Pancreatic beta-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A Diabetes published ahead of print April 11, 2013, doi:10.2337/db12-1394
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Original Research:
• Aimee J. Varewijck,
• Hannele Yki-Järvinen,
• Ronald Schmidt,
• Norbert Tennagels,
• and Joseph A.M.J.L. Janssen
Concentrations of Insulin Glargine and Its Metabolites During Long-Term Insulin Therapy in Type 2 Diabetic Patients and Comparison of Effects of Insulin Glargine, Its Metabolites, IGF-I, and Human Insulin on Insulin and IGF-I Receptor Signaling Diabetes published ahead of print April 8, 2013, doi:10.2337/db12-1773
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Original Research:
• H. Siebe Spijker,
• Raimond B.G. Ravelli,
• A. Mieke Mommaas-Kienhuis,
• Aart A. van Apeldoorn,
• Marten A. Engelse,
• Arnaud Zaldumbide,
• Susan Bonner-Weir,
• Ton J. Rabelink,
• Rob C. Hoeben,
• Hans Clevers,
• Christine L. Mummery,
• Françoise Carlotti,
• and Eelco J.P. de Koning
Conversion of mature human β-cells into glucagon-producing α-cells Diabetes published ahead of print April 8, 2013, doi:10.2337/db12-1001
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• Yuvaraj Mahendran,
• Jagadish Vangipurapu,
• Henna Cederberg,
• Alena Stančáková,
• Jussi Pihlajamäki,
• Pasi Soininen,
• Antti J. Kangas,
• Jussi Paananen,
• Mete Civelek,
• Niyas K. Saleem,
• Päivi Pajukanta,
• Aldons J. Lusis,
• Lori L. Bonnycastle,
• Mario A. Morken,
• Francis S. Collins,
• Karen L. Mohlke,
• Michael Boehnke,
• Mika Ala-Korpela,
• Johanna Kuusisto,
• and Markku Laakso
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1363
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Original Research:
• Farah Lizotte,
• Martin Paré,
• Benoit Denhez,
• Michael Leitges,
• Andréanne Guay,
• and Pedro Geraldes
PKCδ impaired vessel formation and angiogenic factor expression in diabetic ischemic limb Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1432
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Original Research:
• Anna Jonsson,
• Claes Ladenvall,
• Tarunveer Singh Ahluwalia,
• Jasmina Kravic,
• Ulrika Krus,
• Jalal Taneera,
• Bo Isomaa,
• Tiinamaija Tuomi,
• Erik Renström,
• Leif Groop,
• and Valeriya Lyssenko
Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1627
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Original Research:
• Sara F. Michaliszyn,
• Riccardo C. Bonadonna,
• Lindsey A. Sjaarda,
• SoJung Lee,
• Lama Farchoukh,
• and Silva A. Arslanian
β-cell Lipotoxicity in Response to Free Fatty Acid Elevation in Youth: African American versus Caucasian Contrast Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1664
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Original Research:
• Genevieve Marcelin,
• Shun-Mei Liu,
• Gary J. Schwartz,
• and Streamson Chua
Identification of a loss-of-function mutation in Ube2l6 associated with obesity resistance Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1054
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Original Research:
• Assaad A. Eid,
• Bridget M. Ford,
• Basant Bhandary,
• Rita Cavagliery,
• Karen Block,
• Jeffrey L. Barnes,
• Yves Gorin,
• Goutam Ghosh Choudhury,
• and Hanna E. Abboud
mTOR Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1504
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Original Research:
• Kristen E. Pauken,
• Marc K. Jenkins,
• Miyuki Azuma,
• and Brian T. Fife
PD-1, but not PD-L1, expressed by islet-reactive CD4⁺ T cells suppresses infiltration of the pancreas during Type 1 Diabetes Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1475
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Original Research:
• Christelle Le Foll,
• Ambrose Dunn-Meynell,
• Sergei Musatov,
• Christophe Magnan,
• and Barry E Levin
FAT/CD36: A major regulator of neuronal fatty acid sensing and energy homeostasis in rats and mice Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1689
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Original Research:
• Lei Jiang,
• Benedicte Brackeva,
• Zhidong Ling,
• Gertjan Kramer,
• Johannes M Aerts,
• Frans Schuit,
• Bart Keymeulen,
• Daniel Pipeleers,
• Frans Gorus,
• and Geert A. Martens
Potential of Protein Phosphatase Inhibitor 1 as Biomarker of pancreatic beta cell injury in vitro and in vivo Diabetes published ahead of print April 4, 2013, doi:10.2337/db12-1507
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Original Research:
• Ge Li,
• John J. Kohorst,
• Wenjuan Zhang,
• Eleonora Laritsky,
• Govindarajan Kunde-Ramamoorthy,
• Maria S. Baker,
• Marta L. Fiorotto,
• and Robert A. Waterland
Early Postnatal Nutrition Determines Adult Physical Activity and Energy Expenditure in Female Mice Diabetes published ahead of print April 1, 2013, doi:10.2337/db12-1306
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Original Research:
• E. Jennifer Weil,
• Gudeta Fufaa,
• Lois I. Jones,
• Tracy Lovato,
• Kevin V. Lemley,
• Robert L. Hanson,
• William C. Knowler,
• Peter H. Bennett,
• Berne Yee,
• Bryan D. Myers,
• and Robert G. Nelson
Effect of Losartan on Prevention and Progression of Early Diabetic Nephropathy in American Indians With Type 2 Diabetes Diabetes published ahead of print April 1, 2013, doi:10.2337/db12-1512
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Original Research:
• Matheni Sathananthan,
• Luca P. Farrugia,
• John M. Miles,
• Francesca Piccinini,
• Chiara Dalla Man,
• Alan R. Zinsmeister,
• Claudio Cobelli,
• Robert A. Rizza,
• and Adrian Vella
Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function and Glucose Metabolism in Non-Diabetic Subjects Diabetes published ahead of print April 1, 2013, doi:10.2337/db13-0140
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Original Research:
• Maria J. Ribeiro,
• Joana F. Sacramento,
• Constancio Gonzalez,
• Maria P. Guarino,
• Emília C Monteiro,
• and Sílvia V. Conde
Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets Diabetes published ahead of print March 25, 2013, doi:10.2337/db12-1463
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Original Research:
• Larissa W. van Golen,
• Marc C. Huisman,
• Richard G. Ijzerman,
• Nikie J. Hoetjes,
• Lothar A. Schwarte,
• Adriaan A. Lammertsma,
• and Michaela Diamant
Positron emission tomography measured cerebral blood flow and glucose metabolism are decreased in human type 1 diabetes Diabetes published ahead of print March 25, 2013, doi:10.2337/db12-1159
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Original Research:
• Chitoku Toda,
• Tetsuya Shiuchi,
• Haruaki Kageyama,
• Shiki Okamoto,
• Eulalia A. Coutinho,
• Tatsuya Sato,
• Yuko Okamatsu-Ogura,
• Shigefumi Yokota,
• Kazuyo Takagi,
• Lijun Tang,
• Kumiko Saito,
• Seiji Shioda,
• and Yasuhiko Minokoshi
Extracellular Signal–Regulated Kinase in the Ventromedial Hypothalamus Mediates Leptin-Induced Glucose Uptake in Red-Type Skeletal Muscle Diabetes published ahead of print March 25, 2013, doi:10.2337/db12-1629
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Original Research:
• Alexandra E Butler,
• Martha Campbell-Thompson,
• Tatyana Gurlo,
• David W Dawson,
• Mark Atkinson,
• and Peter C Butler
Marked Expansion of Exocrine and Endocrine Pancreas with Incretin Therapy in Humans with increased Exocrine Pancreas Dysplasia and the potential for Glucagon-producing Neuroendocrine Tumors Diabetes published ahead of print March 22, 2013, doi:10.2337/db12-1686
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Original Research:
• Yujie Li,
• Yaohui Nie,
• Ynes Helou,
• Guoxian Ding,
• Bin Feng,
• Gang Xu,
• Arthur Salomon,
• and Haiyan Xu
Identification of sucrose non-fermenting related kinase (SNRK) as a suppressor of adipocyte inflammation Diabetes published ahead of print March 21, 2013, doi:10.2337/db12-1081
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Original Research:
• Saul Genuth,
• Jye-Yu C. Backlund,
• Margaret Bayless,
• David A. Bluemke,
• Patricia A. Cleary,
• Jill Crandall,
• John M. Lachin,
• Joao A.C. Lima,
• Cuilian Miao,
• and Evrim B. Turkbey
Effects of Prior Intensive versus Conventional Therapy and History of Glycemia on Cardiac Function in Type 1 Diabetes in the DCCT/EDIC Diabetes published ahead of print March 21, 2013, doi:10.2337/db12-0546
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Original Research:
• Larbi Dridi,
• Volkan Seyrantepe,
• Anne Fougerat,
• Xuefang Pan,
• Éric Bonneil,
• Pierre Thibault,
• Allain Moreau,
• Grant A. Mitchell,
• Nikolaus Heveker,
• Christopher W. Cairo,
• Tarik Issad,
• Alexander Hinek,
• and Alexey V. Pshezhetsky
Positive Regulation of Insulin Signaling by Neuraminidase 1 Diabetes published ahead of print March 21, 2013, doi:10.2337/db12-1825
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Original Research:
• Anne D Hafstad,
• Jim Lund,
• Elin Hadler-Olsen,
• Anje C Höper,
• Terje S Larsen,
• and Ellen Aasum
High and moderate intensity training normalizes ventricular function and mechanoenergetics in diet-induced obese mice Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1580
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Original Research:
• Yen-Hao Chen,
• Saleh Heneidi,
• Jung-Min Lee,
• Lawrence C. Layman,
• David W. Stepp,
• Gloria Mabel Gamboa,
• Bo-Shiun Chen,
• Gregorio Chazenbalk,
• and Ricardo Azziz
miRNA-93 inhibits GLUT4 and is overexpressed in adipose tissue of Polycystic Ovary Syndrome patients and women with insulin resistance Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-0963
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Original Research:
• Jetro J. Tuulari,
• Henry K. Karlsson,
• Jussi Hirvonen,
• Jarna C. Hannukainen,
• Marco Bucci,
• Mika Helmiö,
• Jari Ovaska,
• Minna Soinio,
• Paulina Salminen,
• Nina Savisto,
• Lauri Nummenmaa,
• and Pirjo Nuutila
Weight loss after bariatric surgery reverses insulin-induced increases in brain glucose metabolism of the morbidly obese Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1460
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Original Research:
• Rita E. Mirza,
• Milie M. Fang,
• William J. Ennis,
• and Timothy J. Koh
Blocking IL-1β Induces a Healing-associated Wound Macrophage Phenotype and Improves Healing in Type-2 Diabetes Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1450
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Original Research:
• Nathalie M. Fiaschi-Taesch,
• Jeffrey W. Kleinberger,
• Fatimah Salim,
• Ronnie Troxell,
• Rachel Wills,
• Mansoor Tanwir,
• Gabriella Casinelli,
• Amy E. Cox,
• Karen K. Takane,
• Donald K. Scott,
• and Andrew F. Stewart
A Human Pancreatic Beta Cell G1/S Molecule Cell Cycle Atlas Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-0777
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Original Research:
• Nathalie M. Fiaschi-Taesch,
• Jeffrey W. Kleinberger,
• Fatimah Salim,
• Ronnie Troxell,
• Rachel Wills,
• Mansoor Tanwir,
• Gabriella Casinelli,
• Amy E. Cox,
• Karen K. Takane,
• Harish Srinivas,
• Donald K. Scott,
• and Andrew F. Stewart
Cytoplasmic-Nuclear Trafficking of G1/S Cell Cycle Molecules and Adult Human Beta Cell Replication: A Revised Model of Human Beta Cell G1/S Control Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-0778
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Original Research:
• Sara Ramírez,
• Luís Martins,
• Jordi Jacas,
• Patricia Carrasco,
• Macarena Pozo,
• Josep Clotet,
• Dolors Serra,
• Fausto G. Hegardt,
• Carlos Diéguez,
• Miguel López,
• and Núria Casals
Hypothalamic ceramide levels regulated by CPT1C mediate the orexigenic effect of ghrelin Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1451
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Original Research:
• David L. Morris,
• Kae Won Cho,
• Jennifer L. DelProposto,
• Kelsie E. Oatmen,
• Lynn M. Geletka,
• Gabriel Martinez-Santibanez,
• Kanakadurga Singer,
• and Carey N. Lumeng
Adipose Tissue Macrophages Function as Antigen Presenting Cells and Regulate Adipose Tissue CD4+ T Cells in Mice Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1404
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Original Research:
• Masaru Akiyama,
• Chong Wee Liew,
• Shusheng Lu,
• Jiang Hu,
• Rachael Martinez,
• Ben Hambro,
• Robert T. Kennedy,
• and Rohit N. Kulkarni
X-box binding protein 1 is essential for insulin regulation of pancreatic alpha cell function Diabetes published ahead of print March 14, 2013, doi:10.2337/db12-1747
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Original Research:
• Paolo Tessari,
• Diego Cecchet,
• Carlo Artusi,
• Monica Vettore,
• Renato Millioni,
• Mario Plebani,
• Lucia Puricelli,
• and Monica Vedovato
Roles of insulin, age, and asymmetric dimethylarginine, on nitric oxide synthesis in vivo Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-1127
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Original Research:
• Brittanie J. Atkinson,
• Beth A. Griesel,
• Caleb D. King,
• Miranda A. Josey,
• and Ann Louise Olson
Moderate GLUT4 overexpression improves insulin sensitivity and fasting triglyceridemia in high fat fed transgenic mice Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-1146
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Original Research:
• Omid Tavana,
• Nahum Puebla-Osorio,
• Jiseong Kim,
• Mei Sang,
• Stella Jang,
• and Chengming Zhu
Ku70 functions in addition to nonhomologous end joining in pancreatic beta-cells: A connection to beta-catenin regulation Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-1218
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Original Research:
• Kumi Kimura,
• Yusuke Nakamura,
• Yuka Inaba,
• Michihiro Matsumoto,
• Yoshiaki Kido,
• Shun-ichiro Asahara,
• Tomokazu Matsuda,
• Hiroshi Watanabe,
• Akifumi Maeda,
• Fuyuhiko Inagaki,
• Chisato Mukai,
• Kiyoshi Takeda,
• Shizuo Akira,
• Tsuguhito Ota,
• Hajime Nakabayashi,
• Shuichi Kaneko,
• Masato Kasuga,
• and Hiroshi Inoue
Histidine augments the suppression of hepatic glucose production by central insulin action Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-1701
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Original Research:
• Shaoqing Lei,
• Haobo Li,
• Jinjin Xu,
• Yanan Liu,
• Xia Gao,
• Junwen Wang,
• Kwok F.J. Ng,
• Wayne Bond Lau,
• Xin-liang Ma,
• Brian Rodrigues,
• Michael G. Irwin,
• and Zhengyuan Xia
Hyperglycemia-induced PKCβ₂ Activation Induces Diastolic Cardiac Dysfunction in Diabetic Rats by Impairing Caveolin-3 Expression and Akt/eNOS Signaling Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-1391
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Original Research:
• Cristina Hernández,
• Marta García-Ramírez,
• Lidia Corraliza,
• Jimena Fernández-Carneado,
• Josep Farrera-Sinfreu,
• Berta Ponsati,
• Águeda González-Rodríguez,
• Ángela Martínez-Valverde,
• and Rafael Simó
Topical administration of somatostatin prevents retinal neurodegeneration in experimental diabetes Diabetes published ahead of print March 8, 2013, doi:10.2337/db12-0926
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Original Research:
• Henry A. Erlich,
• Ana Maria Valdes,
• Shana McDevitt,
• Birgitte B. Simen,
• Lisbeth A. Blake,
• Kim R. McGowan,
• John A. Todd,
• Stephen S. Rich,
• and Janelle Noble
Next Generation Sequencing Reveals the Association of DRB3*02:02 with Type I Diabetes Diabetes published ahead of print March 5, 2013, doi:10.2337/db12-1387
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Original Research:
• Paolo Monti,
• Cristina Brigatti,
• Miriam Krasmann,
• Anette G Ziegler,
• and Ezio Bonifacio
Concentration and activity of the soluble form of the Interleukin-7 Receptor alpha in type I diabetes identifies an interplay between hyperglycemia and immune function Diabetes published ahead of print March 1, 2013, doi:10.2337/db12-1726
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Original Research:
• Qian Zhang,
• Junjie Yu,
• Bin Liu,
• Ziquan Lv,
• Tingting Xia,
• Fei Xiao,
• Shanghai Chen,
• and Feifan Guo
Central activating transcription factor (ATF4) regulates hepatic insulin resistance in mice via S6K1 signaling and the vagus nerve Diabetes published ahead of print March 1, 2013, doi:10.2337/db12-1050
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Original Research:
• Bettina Nowotny,
• Lejla Zahiragic,
• Dorothea Krog,
• Peter J. Nowotny,
• Christian Herder,
• Maren Carstensen,
• Toru Yoshimura,
• Julia Szendroedi,
• Esther Phielix,
• Peter Schadewaldt,
• Nanette C. Schloot,
• Gerald I. Shulman,
• and Michael Roden
Mechanisms underlying the onset of oral lipid-induced skeletal muscle insulin resistance in humans Diabetes published ahead of print March 1, 2013, doi:10.2337/db12-1179
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Original Research:
• Changyun Hu,
• Heyuan Ding,
• Xiaojun Zhang,
• F Susan Wong,
• and Li Wen
Combination treatment with anti-CD20 and oral anti-CD3 prevents and reverses autoimmune diabetes Diabetes published ahead of print February 27, 2013, doi:10.2337/db12-1175
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Original Research:
• Ling Hinshaw,
• Chiara Dalla Man,
• Debashis K. Nandy,
• Ahmed Saad,
• Adil E. Bharucha,
• James A. Levine,
• Robert A. Rizza,
• Rita Basu,
• Rickey E Carter,
• Claudio Cobelli,
• Yogish C. Kudva,
• and Ananda Basu
Diurnal Pattern of Insulin Action in Type 1 diabetes: Implications for a Closed Loop System Diabetes published ahead of print February 27, 2013, doi:10.2337/db12-1759
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Original Research:
• Sebastian Martini,
• Viji Nair,
• Sanjeevkumar R. Patel,
• Felix Eichinger,
• Robert G. Nelson,
• E. Jennifer Weil,
• Marcus G. Pezzolesi,
• Andrzej S. Krolewski,
• Ann Randolph,
• Benjamin J. Keller,
• Thomas Werner,
• and Matthias Kretzler
From SNP to Transcriptional Mechanism: A Model for FRMD3 in Diabetic Nephropathy Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1416
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Original Research:
• Christina Koutsari,
• Manpreet S. Mundi,
• Asem H. Ali,
• Bruce W. Patterson,
• and Michael D. Jensen
Systemic Free Fatty Acid Disposal into Very-Low-Density Lipoprotein Triglycerides Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1557
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Original Research:
• Hilary E Wilson-Pérez,
• Adam P Chambers,
• Karen K Ryan,
• Bailing Li,
• Darleen A Sandoval,
• Doris Stoffers,
• Daniel J Drucker,
• Diego Pérez-Tilve,
• and Randy J Seeley
Vertical Sleeve Gastrectomy is Effective in Two Genetic Mouse Models of Glucagon-like Peptide-1 Receptor Deficiency Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1498
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Original Research:
• Jessica T.Y. Yue,
• Michael C. Riddell,
• Elena Burdett,
• David H. Coy,
• Suad Efendic,
• and Mladen Vranic
Amelioration of Hypoglycemia via Somatostatin Receptor Type 2 Antagonism in Recurrently Hypoglycemic Diabetic Rats Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1523
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Original Research:
• Ken T. Coppieters,
• Natalie Amirian,
• Philippe P. Pagni,
• Carmen Baca Jones,
• Anna Wiberg,
• Stanley Lasch,
• Edith Hintermann,
• Urs Christen,
• and Matthias G. von Herrath
Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic CTL to pancreatic islets in a virally induced autoimmune diabetes model Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1370
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Original Research:
• Jing Luo,
• Ling Zhao,
• Aaron Yun Chen,
• Xiaohui Zhang,
• Jin Zhu,
• Jiagang Zhao,
• Hong Ouyang,
• Hongrong Luo,
• Yaojun Song,
• Janet Lee,
• Shrena Patel,
• Peter X. Shaw,
• SriniVas Sadda,
• Yehong Zhuo,
• Michael G. Rosenfeld,
• and Kang Zhang
TCF7L2 Variation and Proliferative Diabetic Retinopathy Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1093
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Original Research:
• Michael D. Dennis,
• Jeffrey S. Shenberger,
• Bruce A. Stanley,
• Scot R. Kimball,
• and Leonard S. Jefferson
Hyperglycemia Mediates a Shift from Cap-Dependent to Cap-Independent Translation via a 4E-BP1 Dependent Mechanism Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1453
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Original Research:
• Anton Shostak,
• Judit Meyer-Kovac,
• and Henrik Oster
Circadian regulation of lipid mobilization in white adipose tissues Diabetes published ahead of print February 22, 2013, doi:10.2337/db12-1449
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Original Research:
• Cheng-Che E. Lan,
• Ching-Shuang Wu,
• Shu-Mei Huang,
• I-Hui Wu,
• and Gwo-Shing Chen
High-glucose environment enhanced oxidative stress and increased interleukin-8 secretion from keratinocytes: New insights on impaired diabetic wound healing Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1714
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Original Research:
• Frank A Duca,
• Yassine Sakar,
• and Mihai Covasa
Combination of obesity and high-fat feeding diminishes sensitivity to GLP-1R agonist, Exendin-4 Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1204
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Original Research:
• Zhiying Li,
• Sarah F. Schmidt,
• and Jeffrey M. Friedman
Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-0901
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Original Research:
• Yuguang Zhao,
• Yi Tan,
• Shugang Xi,
• Yunqian Li,
• Cai Li,
• Jiuwei Cui,
• Xiaoqing Yan,
• Xiaokun Li,
• Guanjun Wang,
• Wei Li,
• and Lu Cai
A novel mechanism by which SDF-1β protects cardiac cells from palmitate-induced ER stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated IL-6 generation Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1233
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Original Research:
• Naoki Kumashiro,
• Sara A. Beddow,
• Daniel F. Vatner,
• Sachin K. Majumdar,
• Jennifer L. Cantley,
• Fitsum Guebre-Egziabher,
• Ioana Fat,
• Blas Guigni,
• Michael J. Jurczak,
• Andreas L. Birkenfeld,
• Mario Kahn,
• Bryce K. Perler,
• Michelle A. Puchowicz,
• Vara Prasad Manchem,
• Sanjay Bhanot,
• Christopher D. Still,
• Glenn S. Gerhard,
• Kitt F. Petersen,
• Gary W. Cline,
• Gerald I. Shulman,
• and Varman T. Samuel
Targeting pyruvate carboxylase reduces gluconeogenesis and adiposity and improves insulin resistance Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1311
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Original Research:
• Monika Haemmerle,
• Thomas Keller,
• Gerda Egger,
• Helga Schachner,
• Carl Walter Steiner,
• Dejan Stokic,
• Christoph Neumayer,
• Markus K. Brown,
• Dontscho Kerjaschki,
• and Brigitte Hantusch
Enhanced Lymph Vessel Density, Remodelling and Inflammation is Reflected by Gene Expression Signatures in Dermal Lymphatic Endothelial Cells in Type 2 Diabetes Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-0844
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Original Research:
• Laura M. Pérez,
• Aurora Bernal,
• Nuria San Martín,
• Margarita Lorenzo,
• Sonia Fernández-Veledo,
• and Beatriz G. Gálvez
Metabolic rescue of obese adipose-derived stems cells by Lin28/Let7 pathway Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1220
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Original Research:
• Qing Zhong and
• Renu A. Kowluru
Regulation of matrix metallopeptidase-9 by epigenetic modifications, and the development of diabetic retinopathy Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1141
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Original Research:
• Aonghus O’Loughlin,
• Mangesh Kulkarni,
• Michael Creane,
• Erin Vaughan,
• Emma Mooney,
• Georgina Shaw,
• Mary Murphy,
• Peter Dockery,
• Abhay Pandit,
• and Timothy O’Brien
Topical Administration of Allogeneic Mesenchymal Stem Cells Seeded in a Collagen Scaffold Augments Wound Healing and Increases Angiogenesis in the Diabetic Rabbit Ulcer Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1822
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Original Research:
• Patrick P.L. Lam,
• Mitsuyo Ohno,
• Subhankar Dolai,
• Yu He,
• Tairan Qin,
• Tao Liang,
• Dan Zhu,
• Youhou Kang,
• Yunfeng Liu,
• Maria Kauppi,
• Li Xie,
• Wilson C.Y. Wan,
• Na-Rhum Bin,
• Shuzo Sugita,
• Vesa M. Olkkonen,
• Noriko Takahashi,
• Haruo Kasai,
• and Herbert Y. Gaisano
Munc18b is a major mediator of insulin exocytosis in rat pancreatic β-cells Diabetes published ahead of print February 19, 2013, doi:10.2337/db12-1380
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Original Research:
• Wencheng Zhang,
• Qilong Wang,
• Ping Song,
• and Minghui Zou
Liver Kinase B1 Is Required for White Adipose Tissue Growth and Differentiation Diabetes published ahead of print February 8, 2013, doi:10.2337/db12-1229
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Original Research:
• Mario Galgani,
• Rosa Nugnes,
• Dario Bruzzese,
• Francesco Perna,
• Veronica De Rosa,
• Claudio Procaccini,
• Enza Mozzillo,
• Corrado M Cilio,
• Ake Lernmark,
• Helena Elding Larsson,
• Antonio La Cava,
• Adriana Franzese,
• and Giuseppe Matarese
Meta-immunological profiling of children with type 1 diabetes identifies new biomarkers to monitor disease progression Diabetes published ahead of print February 8, 2013, doi:10.2337/db12-1273
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Original Research:
• Jordi Lanuza-Masdeu,
• M. Isabel Arévalo,
• Cristina Vila,
• Albert Barberà,
• Ramon Gomis,
• and Carme Caelles
In vivo JNK activation in pancreatic β-cells leads to glucose intolerance caused by insulin resistance in pancreas Diabetes published ahead of print January 24, 2013, doi:10.2337/db12-1097
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