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Research ArticleOriginal Research

Transient B Cell Depletion Combined with Apoptotic Donor Splenocytes Induces Xeno-specific T and B cell Tolerance to Islet Xenografts

Shusen Wang, James Tasch, Taba Kheradmand, Jodie Ulaszek, Sora Ely, Xiaomin Zhang, Bernhard J. Hering, Stephen D. Miller, Xunrong Luo
DOI: 10.2337/db12-1678 Published 10 July 2013
Shusen Wang
1Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;5Department of Surgery, People's Hospital of Tianjin, Nankai University Affiliated Hospital, Tianjin, 300121, P.R. of China.
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James Tasch
2Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;
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Taba Kheradmand
2Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;
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Jodie Ulaszek
2Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;
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Sora Ely
2Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;
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Xiaomin Zhang
1Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;
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Bernhard J. Hering
3Schulze Diabetes Institute, Department of Surgery, University of Minnesota, Minneapolis, MN 55455, United States.
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Stephen D. Miller
4Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States6Co-senior authors
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Xunrong Luo
1Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;2Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States;4Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States6Co-senior authors
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  • For correspondence: xunrongluo@northwestern.edu

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