Articles:

Organizing glucose disposal: emerging roles of the glycogen targeting subunits of protein phosphatase-1

CB Newgard, MJ Brady, RM O'Doherty, and AR Saltiel
Diabetes 2000 49: 1967-1977. [Abstract] [PDF]  

Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase

LG Fryer, E Hajduch, F Rencurel, IP Salt, HS Hundal, DG Hardie, and D Carling
Diabetes 2000 49: 1978-1985. [Abstract]  

Baculovirus-mediated gene transfer into pancreatic islet cells

L Ma, N Tamarina, Y Wang, A Kuznetsov, N Patel, C Kending, BJ Hering, and LH Philipson
Diabetes 2000 49: 1986-1991. [Abstract]  

Early graft failure of xenogeneic islets in NOD mice is accompanied by high levels of interleukin-1 and low levels of transforming growth factor-beta mRNA in the grafts

CA Gysemans, M Waer, D Valckx, JM Laureys, D Mihkalsky, R Bouillon, and C Mathieu
Diabetes 2000 49: 1992-1997. [Abstract] [PDF]  

Suppression and acceleration of autoimmune diabetes by neutralization of endogenous interleukin-12 in NOD mice

K Fujihira, M Nagata, H Moriyama, H Yasuda, K Arisawa, M Nakayama, S Maeda, M Kasuga, K Okumura, H Yagita, and K Yokono
Diabetes 2000 49: 1998-2006. [Abstract] [PDF]  

Interferon-gamma receptor signaling is dispensable in the development of autoimmune type 1 diabetes in NOD mice

DV Serreze, CM Post, HD Chapman, EA Johnson, B Lu, and PB Rothman
Diabetes 2000 49: 2007-2011. [Abstract] [PDF]  

Dehydroepiandrosterone sulfate and beta-cell function: enhanced glucose-induced insulin secretion and altered gene expression in rodent pancreatic beta-cells

JS Dillon, GC Yaney, Y Zhou, N Voilley, S Bowen, S Chipkin, CR Bliss, V Schultz, FC Schuit, M Prentki, DJ Waxman, and BE Corkey
Diabetes 2000 49: 2012-2020. [Abstract] [PDF]  

Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion

K Yamamoto, J Miyagawa, M Waguri, R Sasada, K Igarashi, M Li, T Nammo, M Moriwaki, A Imagawa, K Yamagata, H Nakajima, M Namba, Y Tochino, T Hanafusa, and Y Matsuzawa
Diabetes 2000 49: 2021-2027. [Abstract] [PDF]  

Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets

CM Antunes, AP Salgado, LM Rosario, and RM Santos
Diabetes 2000 49: 2028-2038. [Abstract] [PDF]  

Hedgehog signaling regulation of insulin production by pancreatic beta-cells

MK Thomas, N Rastalsky, JH Lee, and JF Habener
Diabetes 2000 49: 2039-2047. [Abstract] [PDF]  

Subcellular localization, mobility, and kinetic activity of glucokinase in glucose-responsive insulin-secreting cells

M Stubbs, S Aiston, and L Agius
Diabetes 2000 49: 2048-2055. [Abstract] [PDF]  

beta-cell glucokinase deficiency and hyperglycemia are associated with reduced islet amyloid deposition in a mouse model of type 2 diabetes

S Andrikopoulos, CB Verchere, Y Terauchi, T Kadowaki, and SE Kahn
Diabetes 2000 49: 2056-2062. [Abstract] [PDF]  

Mechanism by which metformin reduces glucose production in type 2 diabetes

RS Hundal, M Krssak, S Dufour, D Laurent, V Lebon, V Chandramouli, SE Inzucchi, WC Schumann, KF Petersen, BR Landau, and GI Shulman
Diabetes 2000 49: 2063-2069. [Abstract] [PDF]  

Overexpression of glutamine: fructose-6-phosphate amidotransferase in the liver of transgenic mice results in enhanced glycogen storage, hyperlipidemia, obesity, and impaired glucose tolerance

G Veerababu, J Tang, RT Hoffman, MC Daniels, LF Hebert, ED Crook, RC Cooksey, and DA McClain
Diabetes 2000 49: 2070-2078. [Abstract] [PDF]  

Effects of skyrin, a receptor-selective glucagon antagonist, in rat and human hepatocytes

JC Parker, RK McPherson, KM Andrews, CB Levy, JS Dubins, JE Chin, PV Perry, B Hulin, DA Perry, T Inagaki, KA Dekker, K Tachikawa, Y Sugie, and JL Treadway
Diabetes 2000 49: 2079-2086. [Abstract] [PDF]  

Paradoxical effect of troglitazone in normal animals: enhancement of adipocyte but reduction of liver insulin sensitivity

MK Dea, GW Van Citters, M Ader, SD Mittelman, AL Sunehag, and RN Bergman
Diabetes 2000 49: 2087-2093. [Abstract] [PDF]  

A high fasting plasma insulin concentration predicts type 2 diabetes independent of insulin resistance: evidence for a pathogenic role of relative hyperinsulinemia

C Weyer, RL Hanson, PA Tataranni, C Bogardus, and RE Pratley
Diabetes 2000 49: 2094-2101. [Abstract] [PDF]  

Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise

EE Blaak, DP van Aggel-Leijssen, AJ Wagenmakers, WH Saris, and MA van Baak
Diabetes 2000 49: 2102-2107. [Abstract] [PDF]  

Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level

E Bakopanos and JE Silva
Diabetes 2000 49: 2108-2115. [Abstract] [PDF]  

Longitudinal compensation for fat-induced insulin resistance includes reduced insulin clearance and enhanced beta-cell response

SD Mittelman, GW Van Citters, SP Kim, DA Davis, MK Dea, M Hamilton-Wessler, and RN Bergman
Diabetes 2000 49: 2116-2125. [Abstract] [PDF]  

A model to explore the interaction between muscle insulin resistance and beta-cell dysfunction in the development of type 2 diabetes

F Mauvais-Jarvis, A Virkamaki, MD Michael, JN Winnay, A Zisman, RN Kulkarni, and CR Kahn
Diabetes 2000 49: 2126-2134. [Abstract] [PDF]  

Prandial glucose effectiveness and fasting gluconeogenesis in insulin-resistant first-degree relatives of patients with type 2 diabetes

MF Nielsen, B Nyholm, A Caumo, V Chandramouli, WC Schumann, C Cobelli, BR Landau, RA Rizza, and O Schmitz
Diabetes 2000 49: 2135-2141. [Abstract] [PDF]  

Pharmacokinetics and pharmacodynamics of subcutaneous injection of long-acting human insulin analog glargine, NPH insulin, and ultralente human insulin and continuous subcutaneous infusion of insulin lispro

M Lepore, S Pampanelli, C Fanelli, F Porcellati, L Bartocci, A Di Vincenzo, C Cordoni, E Costa, P Brunetti, and GB Bolli
Diabetes 2000 49: 2142-2148. [Abstract] [PDF]  

Impaired in vivo stimulation of lipolysis in adipose tissue by selective beta2-adrenergic agonist in obese adolescent girls

S Enoksson, M Talbot, F Rife, WV Tamborlane, RS Sherwin, and S Caprio
Diabetes 2000 49: 2149-2153. [Abstract] [PDF]  

Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat

AL Hevener, D Reichart, and J Olefsky
Diabetes 2000 49: 2154-2159. [Abstract] [PDF]  

Native and modified LDL activate extracellular signal-regulated kinases in mesangial cells

AJ Jenkins, V Velarde, RL Klein, KC Joyce, KD Phillips, RK Mayfield, TJ Lyons, and AA Jaffa
Diabetes 2000 49: 2160-2169. [Abstract] [PDF]  

Defective intracellular antioxidant enzyme production in type 1 diabetic patients with nephropathy

A Ceriello, A Morocutti, F Mercuri, L Quagliaro, M Moro, G Damante, and GC Viberti
Diabetes 2000 49: 2170-2177. [Abstract] [PDF]  

Diabetes in the Goto-Kakizaki rat is accompanied by impaired insulin-mediated myosin-bound phosphatase activation and vascular smooth muscle cell relaxation

OA Sandu, L Ragolia, and N Begum
Diabetes 2000 49: 2178-2189. [Abstract] [PDF]  

APOE polymorphisms and the development of diabetic nephropathy in type 1 diabetes: results of case-control and family-based studies

S Araki, DK Moczulski, L Hanna, LJ Scott, JH Warram, and AS Krolewski
Diabetes 2000 49: 2190-2195. [Abstract] [PDF]  

A common promoter variant of the leptin gene is associated with changes in the relationship between serum leptin and fat mass in obese girls

C Le Stunff, C Le Bihan, NJ Schork, and P Bougneres
Diabetes 2000 49: 2196-2200. [Abstract] [PDF]  

Parental transmission of type 2 diabetes: the Framingham Offspring Study

JB Meigs, LA Cupples, and PW Wilson
Diabetes 2000 49: 2201-2207. [Abstract] [PDF]  

Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships

D Dabelea, RL Hanson, RS Lindsay, DJ Pettitt, G Imperatore, MM Gabir, J Roumain, PH Bennett, and WC Knowler
Diabetes 2000 49: 2208-2211. [Abstract] [PDF]  

Further evidence for a susceptibility locus for type 2 diabetes on chromosome 20q13.1-q13.2

T Klupa, MT Malecki, M Pezzolesi, L Ji, S Curtis, CD Langefeld, SS Rich, JH Warram, and AS Krolewski
Diabetes 2000 49: 2212-2216. [Abstract] [PDF]  

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B

S Nejentsev, Z Gombos, AP Laine, R Veijola, M Knip, O Simell, O Vaarala, HK Akerblom, and J Ilonen
Diabetes 2000 49: 2217-2221. [Abstract] [PDF]  

Cd36 and molecular mechanisms of insulin resistance in the stroke-prone spontaneously hypertensive rat

M Collison, AM Glazier, D Graham, JJ Morton, MH Dominiczak, TJ Aitman, JM Connell, GW Gould, and AF Dominiczak
Diabetes 2000 49: 2222-2226. [Abstract] [PDF]  

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