Perspectives in Diabetes:

Glucose Sensing in Pancreatic ß-Cells: A Model for the Study of Other Glucose-Regulated Cells in Gut, Pancreas, and Hypothalamus

Frans C. Schuit, Peter Huypens, Harry Heimberg, and Daniel G. Pipeleers
Diabetes 2001 50: 1 -11. [Abstract] [Full Text] [PDF]  

Rapid Publications:

Chronic Treatment With 5-Aminoimidazole-4-Carboxamide-1-ß-D-Ribofuranoside Increases Insulin-Stimulated Glucose Uptake and GLUT4 Translocation in Rat Skeletal Muscles in a Fiber Type—Specific Manner

Esben S. Buhl, Niels Jessen, Ole Schmitz, Steen B. Pedersen, Oluf Pedersen, Geoffrey D. Holman, and Sten Lund
Diabetes 2001 50: 12 -17. [Abstract] [Full Text] [PDF]  

Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization

B. Op 't Eijnde, B. Ursø, E.A. Richter, P.L. Greenhaff, and P. Hespel
Diabetes 2001 50: 18 -23. [Abstract] [Full Text] [PDF]  

Metabolism and Signal Transduction:

Serine/Threonine Phosphorylation of IRS-1 Triggers Its Degradation: Possible Regulation by Tyrosine Phosphorylation

Terry M. Pederson, Deborah L. Kramer, and Cristina M. Rondinone
Diabetes 2001 50: 24 -31. [Abstract] [Full Text] [PDF]  

Physiological Differences in Insulin-Like Growth Factor Binding Protein-1 (IGFBP-1) Phosphorylation in IGFBP-1 Transgenic Mice

Keiji Sakai, A. Joseph D'Ercole, Liam J. Murphy, and David R. Clemmons
Diabetes 2001 50: 32 -38. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Variable Effects of Transgenic c-Maf on Autoimmune Diabetes

Mary E. Pauza, Andrea Nguyen, Tom Wolfe, I-Cheng Ho, Laurie H. Glimcher, Matthias von Herrath, and David Lo
Diabetes 2001 50: 39 -46. [Abstract] [Full Text] [PDF]  

Prevention of Diabetes for up to 13 Years by Autoislet Transplantation After Pancreatectomy for Chronic Pancreatitis

R. Paul Robertson, Karla J. Lanz, David E.R. Sutherland, and David M. Kendall
Diabetes 2001 50: 47 -50. [Abstract] [Full Text] [PDF]  

Islet Studies:

Amplitude Modulation of Pulsatile Insulin Secretion by Intrapancreatic Ganglion Neurons

Lei Sha, Johanna Westerlund, Joseph H. Szurszewski, and Peter Bergsten
Diabetes 2001 50: 51 -55. [Abstract] [Full Text] [PDF]  

Glucagon-Like Peptide 1 Stimulates Lipolysis in Clonal Pancreatic ß-Cells (HIT)

Gordon C. Yaney, Vildan N. Civelek, Ann-Marie Richard, Joseph S. Dillon, Jude T. Deeney, James A. Hamilton, Helen M. Korchak, Keith Tornheim, Barbara E. Corkey, and Aubrey E. Boyd, III
Diabetes 2001 50: 56 -62. [Abstract] [Full Text] [PDF]  

A Genetic Defect in ß-Cell Gene Expression Segregates Independently From the fa Locus in the ZDF Rat

Steven C. Griffen, Juehu Wang, and Michael S. German
Diabetes 2001 50: 63 -68. [Abstract] [Full Text] [PDF]  

Distinct Effects of Saturated and Monounsaturated Fatty Acids on ß-Cell Turnover and Function

K. Maedler, G.A. Spinas, D. Dyntar, W. Moritz, N. Kaiser, and Marc Y. Donath
Diabetes 2001 50: 69 -76. [Abstract] [Full Text] [PDF]  

Cell-Permeable Peptide Inhibitors of JNK: Novel Blockers of ß-Cell Death

Christophe Bonny, Anne Oberson, Stéphanie Negri, Christelle Sauser, and Daniel F. Schorderet
Diabetes 2001 50: 77 -82. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Decreased In Situ Insulin Receptor Dephosphorylation in Hyperglycemia-Induced Insulin Resistance in Rat Adipocytes

Shangguo Tang, Hoang Le-Tien, Barry J. Goldstein, Phillip Shin, Robert Lai, and I. George Fantus
Diabetes 2001 50: 83 -90. [Abstract] [Full Text] [PDF]  

Identification of an Interactive Effect of ß₃- and _2b-Adrenoceptor Gene Polymorphisms on Fat Mass in Caucasian Women

Isabelle J. Dionne, Amy N. Turner, André Tchernof, Toni I. Pollin, Dionyssia Avrithi, Daniel Gray, Alan R. Shuldiner, and Eric T. Poehlman
Diabetes 2001 50: 91 -95. [Abstract] [Full Text] [PDF]  

The Protein-Retaining Effects of Growth Hormone During Fasting Involve Inhibition of Muscle-Protein Breakdown

Helene Nørrelund, K. Sreekumaran Nair, Jens Otto Lunde Jørgensen, Jens Sandahl Christiansen, and Niels Møller
Diabetes 2001 50: 96 -104. [Abstract] [Full Text] [PDF]  

Hypoglycemia Activates Orexin Neurons and Selectively Increases Hypothalamic Orexin-B Levels: Responses Inhibited by Feeding and Possibly Mediated by the Nucleus of the Solitary Tract

Xue J. Cai, Martyn L. Evans, Carolyn A. Lister, Ron A. Leslie, Jonathan R. S. Arch, Shelagh Wilson, and Gareth Williams
Diabetes 2001 50: 105 -112. [Abstract] [Full Text] [PDF]  

Mechanism of Amelioration of Insulin Resistance by ß₃-Adrenoceptor Agonist AJ-9677 in the KK-A^y/Ta Diabetic Obese Mouse Model

Hiroshi Kato, Mayumi Ohue, Kaori Kato, Akinori Nomura, Kaoru Toyosawa, Yasuji Furutani, Satoshi Kimura, and Takashi Kadowaki
Diabetes 2001 50: 113 -122. [Abstract] [Full Text] [PDF]  

Prolonged Inhibition of Muscle Carnitine Palmitoyltransferase-1 Promotes Intramyocellular Lipid Accumulation and Insulin Resistance in Rats

Robert L. Dobbins, Lidia S. Szczepaniak, Brandon Bentley, Victoria Esser, Jeffrey Myhill, and J. Denis McGarry
Diabetes 2001 50: 123 -130. [Abstract] [Full Text] [PDF]  

Effects of Tungstate, a New Potential Oral Antidiabetic Agent, in Zucker Diabetic Fatty Rats

María Carmen Muñoz, Albert Barberà, Jorge Domínguez, Josefa Fernàndez-Alvarez, Ramon Gomis, and Joan J. Guinovart
Diabetes 2001 50: 131 -138. [Abstract] [Full Text] [PDF]  

Exercise-Stimulated Glucose Turnover in the Rat Is Impaired by Glucosamine Infusion

Philip D.G. Miles, Katsuya Higo, and Jerrold M. Olefsky
Diabetes 2001 50: 139 -142. [Abstract] [Full Text] [PDF]  

Expression and Role of Bcl-2 in Rat Blastocysts Exposed to High D-Glucose

Serge Pampfer, Sabine Cordi, Ivo Vanderheyden, Patrick Van Der Smissen, Pierre J. Courtoy, Anne Van Cauwenberge, Henri Alexandre, Isabelle Donnay, and René De Hertogh
Diabetes 2001 50: 143 -149. [Abstract] [Full Text] [PDF]  

Oral Glucose Tolerance Test Minimal Model Indexes of ß-Cell Function and Insulin Sensitivity

Elena Breda, Melissa K. Cavaghan, Gianna Toffolo, Kenneth S. Polonsky, and Claudio Cobelli
Diabetes 2001 50: 150 -158. [Abstract] [Full Text] [PDF]  

Complications:

Obesity and Body Fat Distribution Induce Endothelial Dysfunction by Oxidative Stress: Protective Effect of Vitamin C

Francesco Perticone, Roberto Ceravolo, Mafalda Candigliota, Giorgio Ventura, Saverio Iacopino, Flora Sinopoli, and Pier L. Mattioli
Diabetes 2001 50: 159 -165. [Abstract] [Full Text] [PDF]  

Reduced Vasorelaxant Effect of Carbon Monoxide in Diabetes and the Underlying Mechanisms

Rui Wang, Zunzhe Wang, Lingyun Wu, Salma Toma Hanna, and Robert Peterson-Wakeman
Diabetes 2001 50: 166 -174. [Abstract] [Full Text] [PDF]  

IGF-I mRNA and Signaling in the Diabetic Retina

Chiara Gerhardinger, Kimberly D. McClure, Giulio Romeo, Francesca Podestà, and Mara Lorenzi
Diabetes 2001 50: 175 -183. [Abstract] [Full Text] [PDF]  

Genetics:

Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases

Tony R. Merriman, Heather J. Cordell, Iain A. Eaves, Patrick A. Danoy, Francesca Coraddu, Rachael Barber, Francesco Cucca, Simon Broadley, Stephen Sawcer, Alastair Compston, Paul Wordsworth, Jane Shatford, Steve Laval, Johan Jirholt, Rikard Holmdahl, Argyrios N. Theofilopoulos, Dwight H. Kono, Jaakko Tuomilehto, Eva Tuomilehto-Wolf, Raffaella Buzzetti, Maria Giovanna Marrosu, Dag E. Undlien, Kjersti S. Rønningen, C. Ionesco-Tirgoviste, Julian P. Shield, Fleming Pociot, Jorn Nerup, Chaim O. Jacob, Constantin Polychronakos, Steve C. Bain, and John A. Todd
Diabetes 2001 50: 184 -194. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

The Stimulation-Induced Increase in Skeletal Muscle Glycogen Synthase Content Is Impaired in Carriers of the Glycogen Synthase XbaI Gene Polymorphism

Josée St-Onge, Denis R. Joanisse, and Jean-Aimé Simoneau
Diabetes 2001 50: 195 -198. [Abstract] [Full Text] [PDF]  

Evidence That Insulin is Imprinted in the Human Yolk Sac

Gudrun E. Moore, Sayeda N. Abu-Amero, Gill Bell, Emma L. Wakeling, Amanda Kingsnorth, Philip Stanier, Eric Jauniaux, and Simon T. Bennett
Diabetes 2001 50: 199 -203. [Abstract] [Full Text] [PDF]  

Type 2 Diabetes Locus on 12q15: Further Mapping and Mutation Screening of Two Candidate Genes

Arsun Bektas, Jennifer N. Hughes, James H. Warram, Andrzej S. Krolewski, and Alessandro Doria
Diabetes 2001 50: 204 -208. [Abstract] [Full Text] [PDF]  

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