Rapid Publications:

Loss of the Antiangiogenic Pigment Epithelium-Derived Factor in Patients With Angiogenic Eye Disease

Joachim Spranger, Martin Osterhoff, Manja Reimann, Matthias Möhlig, Michael Ristow, Mary Kay Francis, Vincent Cristofalo, Hans-Peter Hammes, Gillian Smith, Michael Boulton, and Andreas F.H. Pfeiffer
Diabetes 2001 50: 2641 -2645. [Abstract] [Full Text] [PDF]  

Characterization of Allelic and Nucleotide Variation Between the RAGE Gene on Chromosome 6 and a Homologous Pseudogene Sequence to Its 5' Regulatory Region on Chromosome 3: Implications for Polymorphic Studies in Diabetes

Barry I. Hudson, Max H. Stickland, Peter J. Grant, and T. Simon Futers
Diabetes 2001 50: 2646 -2651. [Abstract] [Full Text] [PDF]  

Metabolism and Signal Transduction:

Tissue-Specific Regulation of Mitochondrial and Cytoplasmic Protein Synthesis Rates by Insulin

Yves Boirie, Kevin R. Short, Bo Ahlman, Michael Charlton, and K. Sreekumaran Nair
Diabetes 2001 50: 2652 -2658. [Abstract] [Full Text] [PDF]  

Exercise Training Improves Insulin-Mediated Capillary Recruitment in Association With Glucose Uptake in Rat Hindlimb

Stephen Rattigan, Michelle G. Wallis, Joanne M. Youd, and Michael G. Clark
Diabetes 2001 50: 2659 -2665. [Abstract] [Full Text] [PDF]  

Interplay Between Galanin and Leptin in the Hypothalamic Control of Feeding via Corticotropin-Releasing Hormone and Neuropeptide Y

Gabriela E. Bergonzelli, François P. Pralong, Micheline Glauser, Claudia Cavadas, Eric Grouzmann, and Rolf C. Gaillard
Diabetes 2001 50: 2666 -2672. [Abstract] [Full Text] [PDF]  

Convergence of Pre- and Postsynaptic Influences on Glucosensing Neurons in the Ventromedial Hypothalamic Nucleus

Zhentao Song, Barry E. Levin, Joseph J. McArdle, Nader Bakhos, and Vanessa H. Routh
Diabetes 2001 50: 2673 -2681. [Abstract] [Full Text] [PDF]  

Physiologic Hyperinsulinemia Enhances Human Skeletal Muscle Perfusion by Capillary Recruitment

Matthew Coggins, Jonathan Lindner, Steve Rattigan, Linda Jahn, Elizabeth Fasy, Sanjiv Kaul, and Eugene Barrett
Diabetes 2001 50: 2682 -2690. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Intrinsic Defects in the T-Cell Lineage Results in Natural Killer T-Cell Deficiency and the Development of Diabetes in the Nonobese Diabetic Mouse

Yang Yang, Min Bao, and Ji-Won Yoon
Diabetes 2001 50: 2691 -2699. [Abstract] [Full Text] [PDF]  

Protection From Type 1 Diabetes in the Face of High Levels of Activated Autoaggressive Lymphocytes in a Viral Transgenic Mouse Model Crossed to the SV129 Strain

Matthias G. von Herrath, Tom Wolfe, Ursula Möhrle, Bryan Coon, and Anna Hughes
Diabetes 2001 50: 2700 -2708. [Abstract] [Full Text] [PDF]  

Effects of Streptozocin Diabetes and Diabetes Treatment by Islet Transplantation on In Vivo Insulin Signaling in Rat Heart

Luigi Laviola, Gaetana Belsanti, Alberto M. Davalli, Raffaele Napoli, Sebastio Perrini, Gordon C. Weir, Riccardo Giorgino, and Francesco Giorgino
Diabetes 2001 50: 2709 -2720. [Abstract] [Full Text] [PDF]  

Islet Studies:

Interleukin-1ß Stimulation of c-Jun NH₂-Terminal Kinase Activity in Insulin-Secreting Cells: Evidence for Cytoplasmic Restriction

Christopher D. Major and Bryan A. Wolf
Diabetes 2001 50: 2721 -2728. [Abstract] [Full Text] [PDF]  

Selective Modification of Pyruvate Dehydrogenase Kinase Isoform Expression in Rat Pancreatic Islets Elicited by Starvation and Activation of Peroxisome Proliferator–Activated Receptor-: Implications for Glucose-Stimulated Insulin Secretion

Mary C. Sugden, Karen Bulmer, Daniel Augustine, and Mark J. Holness
Diabetes 2001 50: 2729 -2736. [Abstract] [Full Text] [PDF]  

Phenotyping of Individual Pancreatic Islets Locates Genetic Defects in Stimulus Secretion Coupling to Niddm1i Within the Major Diabetes Locus in GK Rats

Jian-Man Lin, Henrik Ortsäter, Hossein Fakhrai-Rad, Joakim Galli, Holger Luthman, and Peter Bergsten
Diabetes 2001 50: 2737 -2743. [Abstract] [Full Text] [PDF]  

-Interferon Signaling in Pancreatic ß-Cells Is Persistent but Can Be Terminated by Overexpression of Suppressor of Cytokine Signaling-1

Mark M.W. Chong, Helen E. Thomas, and Thomas W.H. Kay
Diabetes 2001 50: 2744 -2751. [Abstract] [Full Text] [PDF]  

Transgenic Overexpression of Hepatocyte Growth Factor in the ß-Cell Markedly Improves Islet Function and Islet Transplant Outcomes in Mice

Adolfo García-Ocaña, Rupangi C. Vasavada, Ana Cebrian, Vasumathi Reddy, Karen K. Takane, Juan-Carlos López-Talavera, and Andrew F. Stewart
Diabetes 2001 50: 2752 -2762. [Abstract] [Full Text] [PDF]  

p57^KIP2 Expression in Normal Islet Cells and in Hyperinsulinism of Infancy

S. A. Kassem, I. Ariel, P. S. Thornton, K. Hussain, V. Smith, K. J. Lindley, A. Aynsley-Green, and B. Glaser
Diabetes 2001 50: 2763 -2769. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Insulin Signal Transduction in Skeletal Muscle From Glucose-Intolerant Relatives With Type 2 Diabetes

Heidi Storgaard, Xiao Mei Song, Christine B. Jensen, Sten Madsbad, Marie Björnholm, Allan Vaag, and Juleen R. Zierath
Diabetes 2001 50: 2770 -2778. [Abstract] [Full Text] [PDF]  

Protection From Obesity and Insulin Resistance in Mice Overexpressing Human Apolipoprotein C1

Miek C. Jong, Peter J. Voshol, Martin Muurling, Vivian E.H. Dahlmans, Johannes A. Romijn, Hanno Pijl, and Louis M. Havekes
Diabetes 2001 50: 2779 -2785. [Abstract] [Full Text] [PDF]  

Overfeeding Rapidly Induces Leptin and Insulin Resistance

Jiali Wang, Silvana Obici, Kimyata Morgan, Nir Barzilai, Zhaohui Feng, and Luciano Rossetti
Diabetes 2001 50: 2786 -2791. [Abstract] [Full Text] [PDF]  

Diabetes-Associated Sustained Activation of the Transcription Factor Nuclear Factor-B

Angelika Bierhaus, Stephan Schiekofer, Markus Schwaninger, Martin Andrassy, Per M. Humpert, Jiang Chen, Mei Hong, Thomas Luther, Thomas Henle, Ingrid Klöting, Michael Morcos, Marion Hofmann, Hans Tritschler, Bernd Weigle, Michael Kasper, Mark Smith, George Perry, Ann-Marie Schmidt, David M. Stern, Hans-Ulrich Häring, Erwin Schleicher, and Peter P. Nawroth
Diabetes 2001 50: 2792 -2808. [Abstract] [Full Text] [PDF]  

PPAR-–Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance

Michèle Guerre-Millo, Christine Rouault, Philippe Poulain, Jocelyne André, Vincent Poitout, Jeffrey M. Peters, Frank J. Gonzalez, Jean-Charles Fruchart, Gérard Reach, and Bart Staels
Diabetes 2001 50: 2809 -2814. [Abstract] [Full Text] [PDF]  

Plasma Glucose–Lowering Effect of Tramadol in Streptozotocin-Induced Diabetic Rats

Juei-Tang Cheng, I-Min Liu, Tzong-Cherng Chi, Thing-Fong Tzeng, Feng-Hwa Lu, and Chih Jen Chang
Diabetes 2001 50: 2815 -2821. [Abstract] [Full Text] [PDF]  

Identification of Novel Genes Differentially Expressed in Omental Fat of Obese Subjects and Obese Type 2 Diabetic Patients

Helena Corominola, Laura J. Conner, Lisa S. Beavers, Robert A. Gadski, Dwayne Johnson, Jose F. Caro, and Ronit Rafaeloff-Phail
Diabetes 2001 50: 2822 -2830. [Abstract] [Full Text] [PDF]  

Acute 2DG-Induced Glucoprivation or Dexamethasone Abolishes 2DG-Induced Glucoregulatory Responses to Subsequent Glucoprivation

Nicole M. Sanders and Sue Ritter
Diabetes 2001 50: 2831 -2836. [Abstract] [Full Text] [PDF]  

Complications:

Effects of Insulin and Antioxidant on Plasma 8-Hydroxyguanine and Tissue 8-Hydroxydeoxyguanosine in Streptozotocin-Induced Diabetic Rats

Kyong Soo Park, Jae Hyeon Kim, Min Seon Kim, Jeong Mi Kim, Suk Kyeong Kim, Jeong Yun Choi, Myung Hee Chung, Boghee Han, Seong Yeon Kim, and Hong Kye Lee
Diabetes 2001 50: 2837 -2841. [Abstract] [Full Text] [PDF]  

A Nonlinear Effect of Hyperglycemia and Current Cigarette Smoking Are Major Determinants of the Onset of Microalbuminuria in Type 1 Diabetes

Laura J. Scott, James H. Warram, Linda S. Hanna, Lori M. B. Laffel, Louise Ryan, and Andrzej S. Krolewski
Diabetes 2001 50: 2842 -2849. [Abstract] [Full Text] [PDF]  

Genetics:

Genome-Wide Linkage Analysis Assessing Parent-of-Origin Effects in the Inheritance of Type 2 Diabetes and BMI in Pima Indians

Robert S. Lindsay, Sayuko Kobes, William C. Knowler, Peter H. Bennett, and Robert L. Hanson
Diabetes 2001 50: 2850 -2857. [Abstract] [Full Text] [PDF]  

HbA_1c Levels Are Genetically Determined Even in Type 1 Diabetes: Evidence From Healthy and Diabetic Twins

Harold Snieder, Pamela A. Sawtell, Lesley Ross, James Walker, Tim D. Spector, and R. David Graham Leslie
Diabetes 2001 50: 2858 -2863. [Abstract] [Full Text] [PDF]  

A Missense Mutation of Pax4 Gene (R121W) Is Associated With Type 2 Diabetes in Japanese

Yoshinori Shimajiri, Tokio Sanke, Hiroto Furuta, Tadashi Hanabusa, Takayuki Nakagawa, Yoshio Fujitani, Yoshitaka Kajimoto, Nobuyuki Takasu, and Kishio Nanjo
Diabetes 2001 50: 2864 -2869. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

Uncoupling Protein 3 Content Is Decreased in Skeletal Muscle of Patients With Type 2 Diabetes

Patrick Schrauwen, Matthijs K.C. Hesselink, Ellen E. Blaak, Lars B. Borghouts, Gert Schaart, Wim H.M. Saris, and Hans A. Keizer
Diabetes 2001 50: 2870 -2873. [Abstract] [Full Text] [PDF]  

Further Mapping of the Idd5.1 Locus for Autoimmune Diabetes in NOD Mice

Salah-Eddine Lamhamedi-Cherradi, Olivier Boulard, Cristina Gonzalez, Najiby Kassis, Diane Damotte, Laure Eloy, Guy Fluteau, Matthieu Lévi-Strauss, and Henri-Jean Garchon
Diabetes 2001 50: 2874 -2878. [Abstract] [Full Text] [PDF]  

Diabetes-Associated HLA-DQ Genes and Birth Weight

Lars C. Stene, Per Magnus, Kjersti S. Rønningen, and Geir Joner
Diabetes 2001 50: 2879 -2882. [Abstract] [Full Text] [PDF]  

Tribute:

Bruce R. Zimmerman, MD: 1942–2001

Christopher D. Saudek and Elizabeth A. Walker
Diabetes 2001 50: 2883 . [Extract] [Full Text] [PDF]  

Errata:

Erratum

Diabetes 2001 50: 2884 . [Extract] [Full Text] [PDF]  

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