Rapid Publications:

Identification of Novel Cytokine-Induced Genes in Pancreatic ß-Cells by High-Density Oligonucleotide Arrays

Alessandra K. Cardozo, Mogens Kruhøffer, Ruth Leeman, Torben Ørntoft, and Décio L. Eizirik
Diabetes 2001 50: 909 -920. [Abstract] [Full Text] [PDF]  

AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle of Subjects With Type 2 Diabetes During Exercise

Nicolas Musi, Nobuharu Fujii, Michael F. Hirshman, Ingvar Ekberg, Sven Fröberg, Olle Ljungqvist, Anders Thorell, and Laurie J. Goodyear
Diabetes 2001 50: 921 -927. [Abstract] [Full Text] [PDF]  

Regulation of the Pancreatic Pro-Endocrine Gene Neurogenin3

Jane C. Lee, Stewart B. Smith, Hirotaka Watada, Joseph Lin, David Scheel, Juehu Wang, Raghavendra G. Mirmira, and Michael S. German
Diabetes 2001 50: 928 -936. [Abstract] [Full Text] [PDF]  

Inhibition of GSK-3 Selectively Reduces Glucose-6-Phosphatase and Phosphoenolpyruvate Carboxykinase Gene Expression

Pamela A. Lochhead, Matthew Coghlan, Simon Q.J. Rice, and Calum Sutherland
Diabetes 2001 50: 937 -946. [Abstract] [Full Text] [PDF]  

Metabolism and Signal Transduction:

Insulin’s Effect on Synthesis Rates of Liver Proteins: A Swine Model Comparing Various Precursors of Protein Synthesis

Bo Ahlman, Michael Charlton, Aizhong Fu, Carole Berg, Peter O’Brien, and K. Sreekumaran Nair
Diabetes 2001 50: 947 -954. [Abstract] [Full Text] [PDF]  

Insulin and Leptin Acutely Regulate Cholesterol Ester Metabolism in Macrophages by Novel Signaling Pathways

Lisa O’Rourke, Steven J. Yeaman, and Peter R. Shepherd
Diabetes 2001 50: 955 -961. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

The Transplanted Fetal Endocrine Pancreas Undergoes an Inherent Sequential Differentiation Similar to That in the Native Pancreas: An Ultrastructural Study in the Pig-to-Mouse Model

Agneta Lukinius and Olle Korsgren
Diabetes 2001 50: 962 -971. [Abstract] [Full Text] [PDF]  

BB Rat Thymocytes Cultured in the Presence of Islets Lose Their Ability to Transfer Autoimmune Diabetes

Barbara J. Whalen, Jan Marounek, Peter Weiser, Michael C. Appel, Dale L. Greiner, John P. Mordes, and Aldo A. Rossini
Diabetes 2001 50: 972 -979. [Abstract] [Full Text] [PDF]  

Adenovirus Early Region 3 (E3) Immunomodulatory Genes Decrease the Incidence of Autoimmune Diabetes in NOD Mice

Shimon Efrat, David Serreze, Anton Svetlanov, Cristina M. Post, Ellis A. Johnson, Kevan Herold, and Marshall Horwitz
Diabetes 2001 50: 980 -984. [Abstract] [Full Text] [PDF]  

Human Anti-CD38 Autoantibodies Raise Intracellular Calcium and Stimulate Insulin Release in Human Pancreatic Islets

Alessandro Antonelli, Germano Baj, Piero Marchetti, Poupak Fallahi, Nicola Surico, Cinzia Pupilli, Fabio Malavasi, and Ele Ferrannini
Diabetes 2001 50: 985 -991. [Abstract] [Full Text] [PDF]  

Islet Study:

Chloride Channels Regulate HIT Cell Volume but Cannot Fully Account for Swelling-Induced Insulin Secretion

Tracie A. Kinard, Paulette B. Goforth, Qing Tao, Mary E. Abood, Jeanette Teague, and Leslie S. Satin
Diabetes 2001 50: 992 -1003. [Abstract] [Full Text] [PDF]  

Defective Glucose-Dependent Insulinotropic Polypeptide Receptor Expression in Diabetic Fatty Zucker Rats

Francis C. Lynn, Nathalie Pamir, Eddy H.C. Ng, Christopher H.S. McIntosh, Timothy J. Kieffer, and Raymond A. Pederson
Diabetes 2001 50: 1004 -1011. [Abstract] [Full Text] [PDF]  

Ca²⁺-Dependent Exocytosis of L-Glutamate by TC6, Clonal Mouse Pancreatic -Cells

Hiroshi Yamada, Masato Otsuka, Mitsuko Hayashi, Shuuichi Nakatsuka, Kazuyuki Hamaguchi, Akitsugu Yamamoto, and Yoshinori Moriyama
Diabetes 2001 50: 1012 -1020. [Abstract] [Full Text] [PDF]  

ß-Cell Mass Dynamics in Zucker Diabetic Fatty Rats: Rosiglitazone Prevents the Rise in Net Cell Death

Diane T. Finegood, M. Dawn McArthur, David Kojwang, Marion J. Thomas, Brian G. Topp, Thomas Leonard, and Robin E. Buckingham
Diabetes 2001 50: 1021 -1029. [Abstract] [Full Text] [PDF]  

The Cephalic Insulin Response to Meal Ingestion in Humans Is Dependent on Both Cholinergic and Noncholinergic Mechanisms and Is Important for Postprandial Glycemia

Bo Ahrén and Jens J. Holst
Diabetes 2001 50: 1030 -1038. [Abstract] [Full Text] [PDF]  

Increased Intracellular Calcium Is Required for Spreading of Rat Islet ß-Cells on Extracellular Matrix

Domenico Bosco, Carmen Gonelle-Gispert, Claes B. Wollheim, Philippe A. Halban, and Dominique G. Rouiller
Diabetes 2001 50: 1039 -1046. [Abstract] [Full Text] [PDF]  

Tissue Inhibitor of Metalloproteinase-1 Prevents Cytokine-Mediated Dysfunction and Cytotoxicity in Pancreatic Islets and ß-cells

Xiao Han, Yujie Sun, Stephen Scott, and David Bleich
Diabetes 2001 50: 1047 -1055. [Abstract] [Full Text] [PDF]  

Proteome Analysis of Interleukin-1ß–Induced Changes in Protein Expression in Rat Islets of Langerhans

P. Mose Larsen, S.J. Fey, M.R. Larsen, A. Nawrocki, H.U. Andersen, H. Kähler, C. Heilmann, M.C. Voss, P. Roepstorff, F. Pociot, A.E. Karlsen, and J. Nerup
Diabetes 2001 50: 1056 -1063. [Abstract] [Full Text] [PDF]  

Pathophysiology:

Overexpressing Human Lipoprotein Lipase in Mouse Skeletal Muscle Is Associated With Insulin Resistance

Luis D.M.C.-B. Ferreira, Leslie K. Pulawa, Dalan R. Jensen, and Robert H. Eckel
Diabetes 2001 50: 1064 -1068. [Abstract] [Full Text] [PDF]  

Altered Nephrogenesis Due to Maternal Diabetes Is Associated With Increased Expression of IGF-II/Mannose-6-Phosphate Receptor in the Fetal Kidney

Kaouthar Amri, Nicole Freund, J.P. Duong Van Huyen, Claudie Merlet-Bénichou, and Martine Lelièvre-Pégorier
Diabetes 2001 50: 1069 -1075. [Abstract] [Full Text] [PDF]  

Effect of 5-Aminoimidazole-4-Carboxamide-1-ß-D-Ribofuranoside Infusion on In Vivo Glucose and Lipid Metabolism in Lean and Obese Zucker Rats

Raynald Bergeron, Stephen F. Previs, Gary W. Cline, Pascale Perret, Raymond R. Russell III, Lawrence H. Young, and Gerald I. Shulman
Diabetes 2001 50: 1076 -1082. [Abstract] [Full Text] [PDF]  

Pioglitazone Ameliorates Tumor Necrosis Factor-–Induced Insulin Resistance by a Mechanism Independent of Adipogenic Activity of Peroxisome Proliferator–Activated Receptor-

Minoru Iwata, Tetsuro Haruta, Isao Usui, Yasumitsu Takata, Atsuko Takano, Tatsuhito Uno, Junko Kawahara, Eiichi Ueno, Toshiyasu Sasaoka, Osamu Ishibashi, and Masashi Kobayashi
Diabetes 2001 50: 1083 -1092. [Abstract] [Full Text] [PDF]  

Troglitazone Induces GLUT4 Translocation in L6 Myotubes

Shin Yonemitsu, Haruo Nishimura, Mitsuyo Shintani, Ryou Inoue, Yuji Yamamoto, Hiroaki Masuzaki, Yoshihiro Ogawa, Kiminori Hosoda, Gen Inoue, Tatsuya Hayashi, and Kazuwa Nakao
Diabetes 2001 50: 1093 -1101. [Abstract] [Full Text] [PDF]  

Effects of Tumor Necrosis Factor- on Insulin Action in Cultured Human Muscle Cells

Reza Halse, Samantha L. Pearson, James G. McCormack, Stephen J. Yeaman, and Roy Taylor
Diabetes 2001 50: 1102 -1109. [Abstract] [Full Text] [PDF]  

Liver-Specific igf-1 Gene Deletion Leads to Muscle Insulin Insensitivity

Shoshana Yakar, Jun-Li Liu, Ana M. Fernandez, Yiping Wu, Andrew V. Schally, Jan Frystyk, Steve D. Chernausek, Wilson Mejia, and Derek Le Roith
Diabetes 2001 50: 1110 -1118. [Abstract] [Full Text] [PDF]  

Effect of Acute and Antecedent Hypoglycemia on Sympathetic Neural Activity and Catecholamine Responsiveness in Normal Rats

William I. Sivitz, Judith A. Herlein, Donald A. Morgan, Brian D. Fink, Bradley G. Phillips, and William G. Haynes
Diabetes 2001 50: 1119 -1125. [Abstract] [Full Text] [PDF]  

Circulating Concentrations of the Adipocyte Protein Adiponectin Are Decreased in Parallel With Reduced Insulin Sensitivity During the Progression to Type 2 Diabetes in Rhesus Monkeys

Kikuko Hotta, Tohru Funahashi, Noni L. Bodkin, Heidi K. Ortmeyer, Yukio Arita, Barbara C. Hansen, and Yuji Matsuzawa
Diabetes 2001 50: 1126 -1133. [Abstract] [Full Text] [PDF]  

Regulation by Insulin of Gene Expression in Human Skeletal Muscle and Adipose Tissue: Evidence for Specific Defects in Type 2 Diabetes

Pierre-Henri Ducluzeau, Noël Perretti, Martine Laville, Fabrizio Andreelli, Nathalie Vega, Jean-Paul Riou, and Hubert Vidal
Diabetes 2001 50: 1134 -1142. [Abstract] [Full Text] [PDF]  

Effect of Experimental Elevation of Free Fatty Acids on Insulin Secretion and Insulin Sensitivity in Healthy Carriers of the Pro12Ala Polymorphism of the Peroxisome Proliferator–Activated Receptor-₂ Gene

Norbert Stefan, Andreas Fritsche, Hans Häring, and Michael Stumvoll
Diabetes 2001 50: 1143 -1148. [Abstract] [Full Text] [PDF]  

Isomer-Specific Antidiabetic Properties of Conjugated Linoleic Acid: Improved Glucose Tolerance, Skeletal Muscle Insulin Action, and UCP-2 Gene Expression

J.W. Ryder, C.P. Portocarrero, X.M. Song, L. Cui, M. Yu, T. Combatsiaris, D. Galuska, D.E. Bauman, D.M. Barbano, M.J. Charron, J.R. Zierath, and K.L. Houseknecht
Diabetes 2001 50: 1149 -1157. [Abstract] [Full Text] [PDF]  

Thiazolidinediones Increase Plasma-Adipose Tissue FFA Exchange Capacity and Enhance Insulin-Mediated Control of Systemic FFA Availability

Nicholas D. Oakes, Pia G. Thalén, Severina M. Jacinto, and Bengt Ljung
Diabetes 2001 50: 1158 -1165. [Abstract] [Full Text] [PDF]  

Complications:

Troglitazone Treatment Increases Plasma Vascular Endothelial Growth Factor in Diabetic Patients and Its mRNA in 3T3-L1 Adipocytes

Masahiro Emoto, Takatoshi Anno, Yutaka Sato, Katsuya Tanabe, Shigeru Okuya, Yukio Tanizawa, Akira Matsutani, and Yoshitomo Oka
Diabetes 2001 50: 1166 -1170. [Abstract] [Full Text] [PDF]  

Upregulation of Glucose Metabolism During Intimal Lesion Formation Is Coupled to the Inhibition of Vascular Smooth Muscle Cell Apoptosis: Role of GSK3ß

Jennifer L. Hall, John C. Chatham, Hagit Eldar-Finkelman, and Gary H. Gibbons
Diabetes 2001 50: 1171 -1179. [Abstract] [Full Text] [PDF]  

Impairment of Coronary Microvascular Dilation in Response to Cold Pressor–Induced Sympathetic Stimulation in Type 2 Diabetic Patients With Abnormal Stress Thallium Imaging

Alain Nitenberg, Séverine Ledoux, Paul Valensi, Régis Sachs, Jean-Raymond Attali, and Isabelle Antony
Diabetes 2001 50: 1180 -1185. [Abstract] [Full Text] [PDF]  

Cardiomyocyte Dysfunction in Sucrose-Fed Rats Is Associated With Insulin Resistance

Kaushik Dutta, Deborah A. Podolin, Michael B. Davidson, and Amy J. Davidoff
Diabetes 2001 50: 1186 -1192. [Abstract] [Full Text] [PDF]  

Diabetic Embryopathy in C57BL/6J Mice: Altered Fetal Sex Ratio and Impact of the Splotch Allele

Antonio F. Machado, Ernest F. Zimmerman, David N. Hovland, Jr., Robert Weiss, and Michael D. Collins
Diabetes 2001 50: 1193 -1199. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

The HLA-DPB1–Associated Component of the IDDM1 and Its Relationship to the Major Loci HLA-DQB1, -DQA1, and -DRB1

Francesco Cucca, Frank Dudbridge, Miriam Loddo, Anna P. Mulargia, Rosannna Lampis, Efisio Angius, Stefano De Virgiliis, Bobby P.C. Koeleman, Stephen C. Bain, Anthony H. Barnett, Frances Gilchrist, Heather Cordell, Ken Welsh, and John A. Todd
Diabetes 2001 50: 1200 -1205. [Abstract] [Full Text] [PDF]  

Modest Overexpression of Neuropeptide Y in the Brain Leads to Obesity After High-Sucrose Feeding

Toshihiro Kaga, Akio Inui, Minoru Okita, Akihiro Asakawa, Naohiko Ueno, Masato Kasuga, Mineko Fujimiya, Noriyasu Nishimura, Rika Dobashi, Yasuo Morimoto, I-Min Liu, and Juei-Tang Cheng
Diabetes 2001 50: 1206 -1210. [Abstract] [Full Text] [PDF]  

A Common Stromal Cell–Derived Factor-1 Chemokine Gene Variant is Associated With the Early Onset of Type 1 Diabetes

Danièle Dubois-Laforgue, Houria Hendel, Sophie Caillat-Zucman, Jean-François Zagury, Cheryl Winkler, Christian Boitard, and José Timsit
Diabetes 2001 50: 1211 -1213. [Abstract] [Full Text] [PDF]  

Polymorphism Screening of Four Genes Encoding Advanced Glycation End-Product Putative Receptors: Association Study With Nephropathy in Type 1 Diabetic Patients

Odette Poirier, Viviane Nicaud, Nathalie Vionnet, Ségolène Raoux, Lise Tarnow, Helen Vlassara, Hans-Henrik Parving, and François Cambien
Diabetes 2001 50: 1214 -1218. [Abstract] [Full Text] [PDF]  

No Evidence for Linkage or for Diabetes-Associated Mutations in the Activin Type 2B Receptor Gene (ACVR2B) in French Patients With Mature-Onset Diabetes of the Young or Type 2 Diabetes

Sophie Dupont, El Habib Hani, Corentin Cras-Méneur, Frédérique De Matos, Stéphane Lobbens, Cécile Lecoeur, Martine Vaxillaire, Raphaël Scharfmann, and Philippe Froguel
Diabetes 2001 50: 1219 -1221. [Abstract] [Full Text] [PDF]  

Letters to the Editor:

Status of Research Funded by the American Diabetes Association: Year 2

Mayer B. Davidson
Diabetes 2001 50: 1222 . [Extract] [Full Text] [PDF]  

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