Rapid Publications:

Successful Reversal of Streptozotocin-Induced Diabetes With Stable Allogeneic Islet Function in a Preclinical Model of Type 1 Diabetes

Judith M. Thomas, Juan L. Contreras, Cheryl A. Smyth, Andrew Lobashevsky, Stacie Jenkins, William J. Hubbard, Devin E. Eckhoff, Scott Stavrou, David M. Neville, Jr., and Francis T. Thomas
Diabetes 2001 50: 1227 -1236. [Abstract] [Full Text] [PDF]  

Metabolism and Signal Transduction:

A Daily Rhythm in Glucose Tolerance: A Role for the Suprachiasmatic Nucleus

Susanne E. la Fleur, Andries Kalsbeek, Joke Wortel, Madelon L. Fekkes, and Ruud M. Buijs
Diabetes 2001 50: 1237 -1243. [Abstract] [Full Text] [PDF]  

Protein Kinase C (PKC)- Activation Inhibits PKC- and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells

Gerolama Condorelli, Giovanni Vigliotta, Alessandra Trencia, Maria Alessandra Maitan, Matilde Caruso, Claudia Miele, Francesco Oriente, Stefania Santopietro, Pietro Formisano, and Francesco Beguinot
Diabetes 2001 50: 1244 -1252. [Abstract] [Full Text] [PDF]  

Hexokinase Isozyme Distribution in Human Skeletal Muscle

Vladimir B. Ritov and David E. Kelley
Diabetes 2001 50: 1253 -1262. [Abstract] [Full Text] [PDF]  

Stimulating Effects of Low-Dose Fructose on Insulin-Stimulated Hepatic Glycogen Synthesis in Humans

Kitt Falk Petersen, Didier Laurent, Chunli Yu, Gary W. Cline, and Gerald I. Shulman
Diabetes 2001 50: 1263 -1268. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Pancreatic Biopsy as a Procedure for Detecting In Situ Autoimmune Phenomena in Type 1 Diabetes: Close Correlation Between Serological Markers and Histological Evidence of Cellular Autoimmunity

Akihisa Imagawa, Toshiaki Hanafusa, Shinji Tamura, Makoto Moriwaki, Naoto Itoh, Koji Yamamoto, Hiromi Iwahashi, Kazuya Yamagata, Masako Waguri, Takao Nanmo, Sae Uno, Hiromu Nakajima, Mitsuyoshi Namba, Sumio Kawata, Jun-ichiro Miyagawa, and Yuji Matsuzawa
Diabetes 2001 50: 1269 -1273. [Abstract] [Full Text] [PDF]  

Peptide and Major Histocompatibility Complex–Specific Breaking of Humoral Tolerance to Native Insulin With the B9-23 Peptide in Diabetes-Prone and Normal Mice

Norio Abiru, Aristides K. Maniatis, Liping Yu, Dongmei Miao, Hiroaki Moriyama, Dale Wegmann, and George S. Eisenbarth
Diabetes 2001 50: 1274 -1281. [Abstract] [Full Text] [PDF]  

Islet Studies:

Evidence That Extrapancreatic GLUT2-Dependent Glucose Sensors Control Glucagon Secretion

Rémy Burcelin and Bernard Thorens
Diabetes 2001 50: 1282 -1289. [Abstract] [Full Text] [PDF]  

High Glucose Causes Apoptosis in Cultured Human Pancreatic Islets of Langerhans: A Potential Role for Regulation of Specific Bcl Family Genes Toward an Apoptotic Cell Death Program

Massimo Federici, Marta Hribal, Lucia Perego, Marco Ranalli, Zaira Caradonna, Carla Perego, Luciana Usellini, Rita Nano, Paolo Bonini, Federico Bertuzzi, Lionel N.J.L. Marlier, Alberto M. Davalli, Orazio Carandente, Antonio E. Pontiroli, Gerry Melino, Piero Marchetti, Renato Lauro, Giorgio Sesti, and Franco Folli
Diabetes 2001 50: 1290 -1301. [Abstract] [Full Text] [PDF]  

Increased Uncoupling Protein-2 Levels in ß-cells Are Associated With Impaired Glucose-Stimulated Insulin Secretion: Mechanism of Action

Catherine B. Chan, Domenica De Leo, Jamie W. Joseph, Timothy S. McQuaid, Xiao Fang Ha, Fang Xu, Robert G. Tsushima, Peter S. Pennefather, Anne Marie F. Salapatek, and Michael B. Wheeler
Diabetes 2001 50: 1302 -1310. [Abstract] [Full Text] [PDF]  

A Neuronal Isoform of Nitric Oxide Synthase Expressed in Pancreatic ß-Cells Controls Insulin Secretion

Anne-Dominique Lajoix, Hubbert Reggio, Thierry Chardès, Sylvie Péraldi-Roux, Florence Tribillac, Michèle Roye, Samuel Dietz, Christophe Broca, Michèle Manteghetti, Gérard Ribes, Claes B. Wollheim, and René Gross
Diabetes 2001 50: 1311 -1323. [Abstract] [Full Text] [PDF]  

Pathophysiology:

GLUT4 Is Reduced in Slow Muscle Fibers of Type 2 Diabetic Patients: Is Insulin Resistance in Type 2 Diabetes a Slow, Type 1 Fiber Disease?

Michael Gaster, Peter Staehr, Henning Beck-Nielsen, Henrick D. Schrøder, and Aase Handberg
Diabetes 2001 50: 1324 -1329. [Abstract] [Full Text] [PDF]  

Ezetimibe, a Potent Cholesterol Absorption Inhibitor, Normalizes Combined Dyslipidemia in Obese Hyperinsulinemic Hamsters

Margaret van Heek, Theodore M. Austin, Constance Farley, John A. Cook, Glen G. Tetzloff, and Harry R. Davis
Diabetes 2001 50: 1330 -1335. [Abstract] [Full Text] [PDF]  

Protein Metabolism in Clinically Stable Adult Cystic Fibrosis Patients With Abnormal Glucose Tolerance

Antoinette Moran, Carlos Milla, Rene Ducret, and K. Sreekumaran Nair
Diabetes 2001 50: 1336 -1343. [Abstract] [Full Text] [PDF]  

Decreased Susceptibility to Fatty Acid–Induced Peripheral Tissue Insulin Resistance in Women

Juan P. Frias, Gina B. Macaraeg, Jachelle Ofrecio, Joseph G. Yu, Jerrold M. Olefsky, and Yolanta T. Kruszynska
Diabetes 2001 50: 1344 -1350. [Abstract] [Full Text] [PDF]  

Type 2 Diabetes Impairs Splanchnic Uptake of Glucose but Does Not Alter Intestinal Glucose Absorption During Enteral Glucose Feeding: Additional Evidence for a Defect in Hepatic Glucokinase Activity

Ananda Basu, Rita Basu, Pankaj Shah, Adrian Vella, C. Michael Johnson, Michael Jensen, K. Sreekumaran Nair, W. Frederick Schwenk, and Robert A. Rizza
Diabetes 2001 50: 1351 -1362. [Abstract] [Full Text] [PDF]  

Assessment of Hepatic Insulin Action in Obese Type 2 Diabetic Patients

Peter Staehr, Ole Hother-Nielsen, Klaus Levin, Jens Juul Holst, and Henning Beck-Nielsen
Diabetes 2001 50: 1363 -1370. [Abstract] [Full Text] [PDF]  

Resistance to Exercise-Induced Increase in Glucose Uptake During Hyperinsulinemia in Insulin-Resistant Skeletal Muscle of Patients With Type 1 Diabetes

Pauliina Peltoniemi, Hannele Yki-Järvinen, Vesa Oikonen, Airi Oksanen, Teemu O. Takala, Tapani Rönnemaa, Matti Erkinjuntti, M. Juhani Knuuti, and Pirjo Nuutila
Diabetes 2001 50: 1371 -1377. [Abstract] [Full Text] [PDF]  

The HIV Protease Inhibitor Indinavir Impairs Sterol Regulatory Element-Binding Protein-1 Intranuclear Localization, Inhibits Preadipocyte Differentiation, and Induces Insulin Resistance

Martine Caron, Martine Auclair, Corinne Vigouroux, Martine Glorian, Claude Forest, and Jacqueline Capeau
Diabetes 2001 50: 1378 -1388. [Abstract] [Full Text] [PDF]  

Increased Fatty Acid Uptake and Altered Fatty Acid Metabolism in Insulin-Resistant Muscle of Obese Zucker Rats

Lorraine Patricia Turcotte, Jason Richard Swenberger, Michelle Zavitz Tucker, and Alice Jane Yee
Diabetes 2001 50: 1389 -1396. [Abstract] [Full Text] [PDF]  

The HIV Protease Inhibitor Indinavir Decreases Insulin- and Contraction-Stimulated Glucose Transport in Skeletal Muscle

Lorraine A. Nolte, Kevin E. Yarasheski, Kentaro Kawanaka, Jonathan Fisher, Ngan Le, and John O. Holloszy
Diabetes 2001 50: 1397 -1401. [Abstract] [Full Text] [PDF]  

The Effect of Systemic Versus Portal Insulin Delivery in Pancreas Transplantation on Insulin Action and VLDL Metabolism

André Carpentier, Bruce W. Patterson, Kristine D. Uffelman, Adria Giacca, Mladen Vranic, Mark S. Cattral, and Gary F. Lewis
Diabetes 2001 50: 1402 -1413. [Abstract] [Full Text] [PDF]  

IGF-1 Overexpression Inhibits the Development of Diabetic Cardiomyopathy and Angiotensin II–Mediated Oxidative Stress

Jan Kajstura, Fabio Fiordaliso, Anna Maria Andreoli, Baosheng Li, Stefano Chimenti, Marvin S. Medow, Federica Limana, Bernardo Nadal-Ginard, Annarosa Leri, and Piero Anversa
Diabetes 2001 50: 1414 -1424. [Abstract] [Full Text] [PDF]  

The HIV Protease Inhibitor Nelfinavir Induces Insulin Resistance and Increases Basal Lipolysis in 3T3-L1 Adipocytes

Assaf Rudich, Sharon Vanounou, Klaris Riesenberg, Michal Porat, Amir Tirosh, Ilana Harman-Boehm, Andrew S. Greenberg, Francisc Schlaeffer, and Nava Bashan
Diabetes 2001 50: 1425 -1431. [Abstract] [Full Text] [PDF]  

Increased Prevalence of Microthromboses in Retinal Capillaries of Diabetic Individuals

Daria Boeri, Michele Maiello, and Mara Lorenzi
Diabetes 2001 50: 1432 -1439. [Abstract] [Full Text] [PDF]  

Transgenic Overexpression of Leptin Rescues Insulin Resistance and Diabetes in a Mouse Model of Lipoatrophic Diabetes

Ken Ebihara, Yoshihiro Ogawa, Hiroaki Masuzaki, Mitsuyo Shintani, Fumiko Miyanaga, Megumi Aizawa-Abe, Tatsuya Hayashi, Kiminori Hosoda, Gen Inoue, Yasunao Yoshimasa, Oksana Gavrilova, Marc L. Reitman, and Kazuwa Nakao
Diabetes 2001 50: 1440 -1448. [Abstract] [Full Text] [PDF]  

Insulin Sensitivity of Suppression of Endogenous Glucose Production Is the Single Most Important Determinant of Glucose Tolerance

Peter N. Båvenholm, Jan Pigon, Claes-Göran Östenson, and Suad Efendic
Diabetes 2001 50: 1449 -1454. [Abstract] [Full Text] [PDF]  

Subcellular Localization of Insulin Receptor Substrate Family Proteins Associated With Phosphatidylinositol 3-Kinase Activity and Alterations in Lipolysis in Primary Mouse Adipocytes From IRS-1 Null Mice

Youki Tsuji, Yasushi Kaburagi, Yasuo Terauchi, Shinobu Satoh, Naoto Kubota, Hiroyuki Tamemoto, Fredric B. Kraemer, Hisahiko Sekihara, Shinichi Aizawa, Yasuo Akanuma, Kazuyuki Tobe, Satoshi Kimura, and Takashi Kadowaki
Diabetes 2001 50: 1455 -1463. [Abstract] [Full Text] [PDF]  

The Antihyperglycemic Drug -Lipoic Acid Stimulates Glucose Uptake via Both GLUT4 Translocation and GLUT4 Activation: Potential Role of p38 Mitogen-Activated Protein Kinase in GLUT4 Activation

Daniel Konrad, Romel Somwar, Gary Sweeney, Karen Yaworsky, Michiko Hayashi, Toolsie Ramlal, and Amira Klip
Diabetes 2001 50: 1464 -1471. [Abstract] [Full Text] [PDF]  

Complications:

Phosphorylation of p38 Mitogen-Activated Protein Kinase Downstream of Bax-Caspase-3 Pathway Leads to Cell Death Induced by High D-Glucose in Human Endothelial Cells

Hironori Nakagami, Ryuichi Morishita, Kei Yamamoto, Shin-ichi Yoshimura, Yoshiaki Taniyama, Motokuni Aoki, Hiroaki Matsubara, Shokei Kim, Yasufumi Kaneda, and Toshio Ogihara
Diabetes 2001 50: 1472 -1481. [Abstract] [Full Text] [PDF]  

Hypoxia Stimulates Osteopontin Expression and Proliferation of Cultured Vascular Smooth Muscle Cells: Potentiation by High Glucose

Chhinder P. Sodhi, Sarojini A. Phadke, Daniel Batlle, and Atul Sahai
Diabetes 2001 50: 1482 -1490. [Abstract] [Full Text] [PDF]  

Hyperglycemia Potentiates Collagen-Induced Platelet Activation Through Mitochondrial Superoxide Overproduction

Sho-ichi Yamagishi, Diane Edelstein, Xue-liang Du, and Michael Brownlee
Diabetes 2001 50: 1491 -1494. [Abstract] [Full Text] [PDF]  

Requirement for p38 and p44/p42 Mitogen-Activated Protein Kinases in RAGE-Mediated Nuclear Factor-B Transcriptional Activation and Cytokine Secretion

Chen-Hsiung Yeh, Lydia Sturgis, Joe Haidacher, Xue-Nong Zhang, Sidney J. Sherwood, Robert J. Bjercke, Ondrej Juhasz, Michael T. Crow, Ronald G. Tilton, and Larry Denner
Diabetes 2001 50: 1495 -1504. [Abstract] [Full Text] [PDF]  

Effects of Novel Polymorphisms in the RAGE Gene on Transcriptional Regulation and Their Association With Diabetic Retinopathy

Barry I. Hudson, Max H. Stickland, T. Simon Futers, and Peter J. Grant
Diabetes 2001 50: 1505 -1511. [Abstract] [Full Text] [PDF]  

Errata:

Errata

Diabetes 2001 50: 1512 . [Extract] [Full Text] [PDF]  

Errata

Diabetes 2001 50: 1512 . [Extract] [Full Text] [PDF]  

Errata

Diabetes 2001 50: 1512 . [Extract] [Full Text] [PDF]  

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