Diabetes -- Table of Contents (August 2001, 50 [8])

Rapid Publications:

Glucose Induces ß-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets: Kathrin Maedler, Giatgen A. Spinas, Roger Lehmann, Pavel Sergeev, Markus Weber, Adriano Fontana, Nurit Kaiser, and Marc Y. Donath
Diabetes 2001 50: 1683 -1690. [Abstract] [Full Text] [PDF]

Insulin Production by Human Embryonic Stem Cells: Suheir Assady, Gila Maor, Michal Amit, Joseph Itskovitz-Eldor, Karl L. Skorecki, and Maty Tzukerman
Diabetes 2001 50: 1691 -1697. [Abstract] [Full Text] [PDF]

Complete Protection of Islets Against Allorejection and Autoimmunity by a Simple Barium-Alginate Membrane: Valérie F. Duvivier-Kali, Abdulkadir Omer, Richard J. Parent, John J. O’Neil, and Gordon C. Weir
Diabetes 2001 50: 1698 -1705. [Abstract] [Full Text] [PDF]

Proteins Linked to a Protein Transduction Domain Efficiently Transduce Pancreatic Islets: Jennifer Embury, Dagmar Klein, Antonello Pileggi, Melina Ribeiro, Sundararajan Jayaraman, R. Damaris Molano, Christopher Fraker, Norma Kenyon, Camillo Ricordi, Luca Inverardi, and Ricardo L. Pastori
Diabetes 2001 50: 1706 -1713. [Abstract] [Full Text] [PDF]

A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans: David E. Cummings, Jonathan Q. Purnell, R. Scott Frayo, Karin Schmidova, Brent E. Wisse, and David S. Weigle
Diabetes 2001 50: 1714 -1719. [Abstract] [Full Text] [PDF]

Metabolism and Signal Transduction:

Glucose Competence of the Hepatoportal Vein Sensor Requires the Presence of an Activated Glucagon-Like Peptide-1 Receptor: Rémy Burcelin, Anabela Da Costa, Daniel Drucker, and Bernard Thorens
Diabetes 2001 50: 1720 -1728. [Abstract] [Full Text] [PDF]

T-Cell Epitope Analysis on the Autoantigen Phogrin (IA-2ß) in the Nonobese Diabetic Mouse: Katalin Kelemen, Dale R. Wegmann, and John C. Hutton
Diabetes 2001 50: 1729 -1734. [Abstract] [Full Text] [PDF]

Expression of GAD65 and Islet Cell Antibody (ICA512) Autoantibodies Among Cytoplasmic ICA+ Relatives Is Associated With Eligibility for the Diabetes Prevention Trial-Type 1: Liping Yu, David D. Cuthbertson, Noel Maclaren, Richard Jackson, Jerry P. Palmer, Tihamer Orban, George S. Eisenbarth, and Jeffrey P. Krischer
Diabetes 2001 50: 1735 -1740. [Abstract] [Full Text] [PDF]

Cytokine Induction of Fas Gene Expression in Insulin-Producing Cells Requires the Transcription Factors NF- ${kappa}$ B and C/EBP: Martine I. Darville and Décio L. Eizirik
Diabetes 2001 50: 1741 -1748. [Abstract] [Full Text] [PDF]

Characterization of Preparations of GAD65, Proinsulin, and the Islet Tyrosine Phosphatase IA-2 for Use in Detection of Autoreactive T-Cells in Type 1 Diabetes: Report of Phase II of the Second International Immunology of Diabetes Society Workshop for Standardization of T-cell Assays in Type 1 Diabetes: Mark Peakman, Timothy I. Tree, Josef Endl, Peter van Endert, Mark A. Atkinson, and Bart O. Roep
Diabetes 2001 50: 1749 -1754. [Abstract] [Full Text] [PDF]

Islet Studies:

Nerve Growth Factor Increases Insulin Secretion and Barium Current in Pancreatic ß-Cells: T. Rosenbaum, M.C. Sánchez-Soto, and M. Hiriart
Diabetes 2001 50: 1755 -1762. [Abstract] [Full Text] [PDF]

Linear Correlation Between the Total Islet Mass and the Volume-Weighted Mean Islet Volume: Maren Skau, Bente Pakkenberg, Karsten Buschard, and Troels Bock
Diabetes 2001 50: 1763 -1770. [Abstract] [Full Text] [PDF]

Inverse Relationship Between Cytotoxicity of Free Fatty Acids in Pancreatic Islet Cells and Cellular Triglyceride Accumulation: Miriam Cnop, Jean Claude Hannaert, Anne Hoorens, Décio L. Eizirik, and Daniel G. Pipeleers
Diabetes 2001 50: 1771 -1777. [Abstract] [Full Text] [PDF]

Acute and Short-Term Administration of a Sulfonylurea (Gliclazide) Increases Pulsatile Insulin Secretion in Type 2 Diabetes: Claus B. Juhl, Niels Pørksen, Steven M. Pincus, Åge P. Hansen, Johannes D. Veldhuis, and Ole Schmitz
Diabetes 2001 50: 1778 -1784. [Abstract] [Full Text] [PDF]

Glucose Metabolism and Pulsatile Insulin Release From Isolated Islets: Johanna Westerlund and Peter Bergsten
Diabetes 2001 50: 1785 -1790. [Abstract] [Full Text] [PDF]

Glycerol-Stimulated Proinsulin Biosynthesis in Isolated Pancreatic Rat Islets via Adenoviral-Induced Expression of Glycerol Kinase Is Mediated via Mitochondrial Metabolism: Robert H. Skelly, Barton Wicksteed, Peter A. Antinozzi, and Christopher J. Rhodes
Diabetes 2001 50: 1791 -1798. [Abstract] [Full Text] [PDF]

IPF1/PDX1 Deficiency and ß-Cell Dysfunction in Psammomys obesus, an Animal With Type 2 Diabetes: Gil Leibowitz, Sarah Ferber, Åsa Apelqvist, Helena Edlund, David J. Gross, Erol Cerasi, Danielle Melloul, and Nurit Kaiser
Diabetes 2001 50: 1799 -1806. [Abstract] [Full Text] [PDF]

Pathophysiology:

Effect of Physiological Hyperinsulinemia on Gluconeogenesis in Nondiabetic Subjects and in Type 2 Diabetic Patients: Amalia Gastaldelli, Elena Toschi, Maura Pettiti, Silvia Frascerra, Alfredo Quiñones-Galvan, Anna Maria Sironi, Andrea Natali, and Ele Ferrannini
Diabetes 2001 50: 1807 -1812. [Abstract] [Full Text] [PDF]

Treatment of Type 2 Diabetes by Adenoviral-Mediated Overexpression of the Glucokinase Regulatory Protein: Eric D. Slosberg, Urvi J. Desai, Barbara Fanelli, Irene St. Denny, Sheila Connelly, Michael Kaleko, Brian R. Boettcher, and Shari L. Caplan
Diabetes 2001 50: 1813 -1820. [Abstract] [Full Text] [PDF]

Alteration in Phosphorylation of P20 Is Associated With Insulin Resistance: Yu Wang, Aimin Xu, Jiming Ye, Edward W. Kraegen, Cynthia A. Tse, and Garth J.S. Cooper
Diabetes 2001 50: 1821 -1827. [Abstract] [Full Text] [PDF]

Low Acute Insulin Secretory Responses in Adult Offspring of People With Early Onset Type 2 Diabetes: Jean-François Gautier, Charlton Wilson, Christian Weyer, Dave Mott, William C. Knowler, Melissa Cavaghan, Kenneth S. Polonsky, Clifton Bogardus, and Richard E. Pratley
Diabetes 2001 50: 1828 -1833. [Abstract] [Full Text] [PDF]

Insulin Secretion and Glucose Kinetics During Exercise With and Without Pharmacological ${alpha}$ ₁- and ${alpha}$ ₂-Receptor Blockade: Pauliina Aarnio, Torsten Lauritsen, and Flemming Dela
Diabetes 2001 50: 1834 -1843. [Abstract] [Full Text] [PDF]

Nonalcoholic Fatty Liver Disease: A Feature of the Metabolic Syndrome: Giulio Marchesini, Mara Brizi, Giampaolo Bianchi, Sara Tomassetti, Elisabetta Bugianesi, Marco Lenzi, Arthur J. McCullough, Stefania Natale, Gabriele Forlani, and Nazario Melchionda
Diabetes 2001 50: 1844 -1850. [Abstract] [Full Text] [PDF]

Glucose Regulates the Transcription of Human Genes Relevant to HDL Metabolism: Responsive Elements for Peroxisome Proliferator–Activated Receptor Are Involved in the Regulation of Phospholipid Transfer Protein: An-Yue Tu and John J. Albers
Diabetes 2001 50: 1851 -1856. [Abstract] [Full Text] [PDF]

Menopause in Type 1 Diabetic Women: Is it Premature?: Janice S. Dorman, Ann R. Steenkiste, Thomas P. Foley, Elsa S. Strotmeyer, James P. Burke, Lewis H. Kuller, and C. Kent Kwoh
Diabetes 2001 50: 1857 -1862. [Abstract] [Full Text] [PDF]

Effects of Pioglitazone on Adipose Tissue Remodeling Within the Setting of Obesity and Insulin Resistance: Christopher J. de Souza, Michele Eckhardt, Karen Gagen, Mei Dong, Wei Chen, Didier Laurent, and Bryan F. Burkey
Diabetes 2001 50: 1863 -1871. [Abstract] [Full Text] [PDF]

Small Increases in Insulin Inhibit Hepatic Glucose Production Solely Caused by an Effect on Glycogen Metabolism: Dale S. Edgerton, Sylvain Cardin, Maya Emshwiller, Doss Neal, Visvanathan Chandramouli, William C. Schumann, Bernard R. Landau, Luciano Rossetti, and Alan D. Cherrington
Diabetes 2001 50: 1872 -1882. [Abstract] [Full Text] [PDF]

Bezafibrate Reduces mRNA Levels of Adipocyte Markers and Increases Fatty Acid Oxidation in Primary Culture of Adipocytes: Àgatha Cabrero, Marta Alegret, Rosa M. Sánchez, Tomás Adzet, Juan C. Laguna, and Manuel Vázquez
Diabetes 2001 50: 1883 -1890. [Abstract] [Full Text] [PDF]

Growth Hormone Induces Cellular Insulin Resistance by Uncoupling Phosphatidylinositol 3-Kinase and Its Downstream Signals in 3T3-L1 Adipocytes: Atsuko Takano, Tetsuro Haruta, Minoru Iwata, Isao Usui, Tatsuhito Uno, Junko Kawahara, Eiichi Ueno, Toshiyasu Sasaoka, and Masashi Kobayashi
Diabetes 2001 50: 1891 -1900. [Abstract] [Full Text] [PDF]

Defective Insulin-Induced GLUT4 Translocation in Skeletal Muscle of High Fat–Fed Rats Is Associated With Alterations in Both Akt/Protein Kinase B and Atypical Protein Kinase C ( ${zeta}$ / ${lambda}$ ) Activities: Frédéric Tremblay, Charles Lavigne, Hélène Jacques, and André Marette
Diabetes 2001 50: 1901 -1910. [Abstract] [Full Text] [PDF]

Blood-to-Brain Glucose Transport, Cerebral Glucose Metabolism, and Cerebral Blood Flow Are Not Increased After Hypoglycemia: Scott A. Segel, Carmine G. Fanelli, Carmen S. Dence, Joanne Markham, Tom O. Videen, Deanna S. Paramore, William J. Powers, and Philip E. Cryer
Diabetes 2001 50: 1911 -1917. [Abstract] [Full Text] [PDF]

Complications:

Angiotensin II Promotes Glucose-Induced Activation of Cardiac Protein Kinase C Isozymes and Phosphorylation of Troponin I: Ashwani Malhotra, Barinder P.S. Kang, Simon Cheung, David Opawumi, and Leonard G. Meggs
Diabetes 2001 50: 1918 -1926. [Abstract] [Full Text] [PDF]

Effect of Antioxidant Treatment of Streptozotocin-Induced Diabetic Rats on Endoneurial Blood Flow, Motor Nerve Conduction Velocity, and Vascular Reactivity of Epineurial Arterioles of the Sciatic Nerve: Lawrence J. Coppey, Jill S. Gellett, Eric P. Davidson, Joyce A. Dunlap, Donald D. Lund, and Mark A. Yorek
Diabetes 2001 50: 1927 -1937. [Abstract] [Full Text] [PDF]

Abnormalities of Retinal Metabolism in Diabetes and Experimental Galactosemia: VII. Effect of Long-Term Administration of Antioxidants on the Development of Retinopathy: Renu A. Kowluru, Jie Tang, and Timothy S. Kern
Diabetes 2001 50: 1938 -1942. [Abstract] [Full Text] [PDF]

Genetics:

Susceptibility and Negative Epistatic Loci Contributing to Type 2 Diabetes and Related Phenotypes in a KK/Ta Mouse Model: Toshihide Shike, Sachiko Hirose, Michimasa Kobayashi, Kazuhiko Funabiki, Toshikazu Shirai, and Yasuhiko Tomino
Diabetes 2001 50: 1943 -1948. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

New Amino Acid Substitutions in the IRS-2 Gene in Finnish and Chinese Subjects With Late-Onset Type 2 Diabetes: Hua Wang, Johanna Rissanen, Raija Miettinen, Päivi Kärkkäinen, Päivi Kekäläinen, Johanna Kuusisto, Leena Mykkänen, Pauli Karhapää, and Markku Laakso
Diabetes 2001 50: 1949 -1951. [Abstract] [Full Text] [PDF]

A Cluster of Three Single Nucleotide Polymorphisms in the 3'-Untranslated Region of Human Glycoprotein PC-1 Gene Stabilizes PC-1 mRNA and Is Associated With Increased PC-1 Protein Content and Insulin Resistance–Related Abnormalities: Lucia Frittitta, Tonino Ercolino, Maura Bozzali, Alessandra Argiolas, Salvo Graci, Maria G. Santagati, Daniela Spampinato, Rosa Di Paola, Carmela Cisternino, Vittorio Tassi, Riccardo Vigneri, Antonio Pizzuti, and Vincenzo Trischitta
Diabetes 2001 50: 1952 -1955. [Abstract] [Full Text] [PDF]