Diabetes -- Table of Contents (October 2002, 51 [10])

Perspectives in Diabetes:

Metabolic and Autocrine Regulation of the Mammalian Target of Rapamycin by Pancreatic ß-Cells: Michael L. McDaniel, Connie A. Marshall, Kirk L. Pappan, and Guim Kwon
Diabetes 2002 51: 2877 -2885. [Abstract] [Full Text] [PDF]

Metabolism and Signal Transduction:

AICAR Administration Causes an Apparent Enhancement of Muscle and Liver Insulin Action in Insulin-Resistant High-Fat-Fed Rats: Miguel A. Iglesias, Ji-Ming Ye, Georgia Frangioudakis, Asish K. Saha, Eva Tomas, Neil B. Ruderman, Gregory J. Cooney, and Edward W. Kraegen
Diabetes 2002 51: 2886 -2894. [Abstract] [Full Text] [PDF]

Troglitazone Antagonizes Metabolic Effects of Glucocorticoids in Humans: Effects on Glucose Tolerance, Insulin Sensitivity, Suppression of Free Fatty Acids, and Leptin: Steven M. Willi, Adele Kennedy, Penny Wallace, Elizabeth Ganaway, Nikki L. Rogers, and W. Timothy Garvey
Diabetes 2002 51: 2895 -2902. [Abstract] [Full Text] [PDF]

Effects of a Novel Glycogen Synthase Kinase-3 Inhibitor on Insulin-Stimulated Glucose Metabolism in Zucker Diabetic Fatty (fa/fa) Rats: Gary W. Cline, Kirk Johnson, Werner Regittnig, Pascale Perret, Effie Tozzo, Linda Xiao, Christine Damico, and Gerald I. Shulman
Diabetes 2002 51: 2903 -2910. [Abstract] [Full Text] [PDF]

Ghrelin Is Not Necessary for Adequate Hormonal Counterregulation of Insulin-Induced Hypoglycemia: Paola Lucidi, Giuseppe Murdolo, Chiara Di Loreto, Arianna De Cicco, Natascia Parlanti, Carmine Fanelli, Fausto Santeusanio, Geremia B. Bolli, and Pierpaolo De Feo
Diabetes 2002 51: 2911 -2914. [Abstract] [Full Text] [PDF]

Coordinated Regulation of Fat-Specific and Liver-Specific Glycerol Channels, Aquaporin Adipose and Aquaporin 9: Hiroshi Kuriyama, Iichiro Shimomura, Ken Kishida, Hidehiko Kondo, Naoki Furuyama, Hitoshi Nishizawa, Norikazu Maeda, Morihiro Matsuda, Hiroyuki Nagaretani, Shinji Kihara, Tadashi Nakamura, Yoshihiro Tochino, Tohru Funahashi, and Yuji Matsuzawa
Diabetes 2002 51: 2915 -2921. [Abstract] [Full Text] [PDF]

Polyunsaturated Fatty Acids and Acetoacetate Downregulate the Expression of the ATP-Binding Cassette Transporter A1: Yoshinari Uehara, Thomas Engel, Zhengchen Li, Christian Goepfert, Stephan Rust, Xiaoqin Zhou, Claus Langer, Christian Schachtrup, Johannes Wiekowski, Stefan Lorkowski, Gerd Assmann, and Arnold von Eckardstein
Diabetes 2002 51: 2922 -2928. [Abstract] [Full Text] [PDF]

Tumor Necrosis Factor- ${alpha}$ Stimulates Lipolysis in Differentiated Human Adipocytes Through Activation of Extracellular Signal-Related Kinase and Elevation of Intracellular cAMP: Hui H. Zhang, Melanie Halbleib, Faiyaz Ahmad, Vincent C. Manganiello, and Andrew S. Greenberg
Diabetes 2002 51: 2929 -2935. [Abstract] [Full Text] [PDF]

Skeletal Muscle Insulin Resistance in Obesity-Associated Type 2 Diabetes in Monkeys Is Linked to a Defect in Insulin Activation of Protein Kinase C- ${zeta}$ / ${lambda}$ / ${iota}$: Mary L. Standaert, Heidi K. Ortmeyer, Mini P. Sajan, Yoshinori Kanoh, Gautam Bandyopadhyay, Barbara C. Hansen, and Robert V. Farese
Diabetes 2002 51: 2936 -2943. [Abstract] [Full Text] [PDF]

Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes: David E. Kelley, Jing He, Elizabeth V. Menshikova, and Vladimir B. Ritov
Diabetes 2002 51: 2944 -2950. [Abstract] [Full Text] [PDF]

Obesity Studies:

Removal of Visceral Fat Prevents Insulin Resistance and Glucose Intolerance of Aging: An Adipokine-Mediated Process?: Ilan Gabriely, Xiao Hui Ma, Xiao Man Yang, Gil Atzmon, Michael W. Rajala, Anders H. Berg, Phillip Scherer, Luciano Rossetti, and Nir Barzilai
Diabetes 2002 51: 2951 -2958. [Abstract] [Full Text] [PDF]

Effect of Weight Loss on Insulin Sensitivity and Intramuscular Long-Chain Fatty Acyl-CoAs in Morbidly Obese Subjects: Joseph A. Houmard, Charles J. Tanner, Chunli Yu, Paul G. Cunningham, Walter J. Pories, Kenneth G. MacDonald, and Gerald I. Shulman
Diabetes 2002 51: 2959 -2963. [Abstract] [Full Text] [PDF]

Low Plasma Adiponectin Concentrations Do Not Predict Weight Gain in Humans: Barbora Vozarova, Norbert Stefan, Robert S. Lindsay, Jonathan Krakoff, William C. Knowler, Tohru Funahashi, Yuji Matsuzawa, Michael Stumvoll, Christian Weyer, and P. Antonio Tataranni
Diabetes 2002 51: 2964 -2967. [Abstract] [Full Text] [PDF]

The Effect of Thiazolidinediones on Plasma Adiponectin Levels in Normal, Obese, and Type 2 Diabetic Subjects: Joseph G. Yu, Sandrine Javorschi, Andrea L. Hevener, Yolanta T. Kruszynska, Rodney A. Norman, Madhur Sinha, and Jerrold M. Olefsky
Diabetes 2002 51: 2968 -2974. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Thymectomy and Radiation-Induced Type 1 Diabetes in Nonlymphopenic BB Rats: Sheela Ramanathan, Marie-Therese Bihoreau, Andrew D. Paterson, Leili Marandi, Dominique Gauguier, and Philippe Poussier
Diabetes 2002 51: 2975 -2981. [Abstract] [Full Text] [PDF]

Islet Studies:

Different Regulated Expression of the Tyrosine Phosphatase-Like Proteins IA-2 and Phogrin by Glucose and Insulin in Pancreatic Islets: Relationship to Development of Insulin Secretory Responses in Early Life: Kristian Löbner, Holger Steinbrenner, Graham A. Roberts, Zhidong Ling, Guo-Cai Huang, Sandra Piquer, Daniel G. Pipeleers, Jochen Seissler, and Michael R. Christie
Diabetes 2002 51: 2982 -2988. [Abstract] [Full Text] [PDF]

Role of NADH Shuttles in Glucose-Induced Insulin Secretion From Fetal ß-Cells: Cynthia Tan, Bernard E. Tuch, Jian Tu, and Shane A. Brown
Diabetes 2002 51: 2989 -2996. [Abstract] [Full Text] [PDF]

Early, Selective, and Marked Loss of Sympathetic Nerves From the Islets of BioBreeder Diabetic Rats: Qi Mei, Thomas O. Mundinger, Ake Lernmark, and Gerald J. Taborsky, Jr
Diabetes 2002 51: 2997 -3002. [Abstract] [Full Text] [PDF]

Overexpression of Parathyroid Hormone-Related Protein Inhibits Pancreatic ß-Cell Death In Vivo and In Vitro: Ana Cebrian, Adolfo García-Ocaña, Karen K. Takane, Darinka Sipula, Andrew F. Stewart, and Rupangi C. Vasavada
Diabetes 2002 51: 3003 -3013. [Abstract] [Full Text] [PDF]

Pathophysiology:

Hyperinsulinemia in African-American Children: Decreased Insulin Clearance and Increased Insulin Secretion and Its Relationship to Insulin Sensitivity: Silva A. Arslanian, Rola Saad, Vered Lewy, Kapriel Danadian, and Janine Janosky
Diabetes 2002 51: 3014 -3019. [Abstract] [Full Text] [PDF]

Independent Association of Type 2 Diabetes and Coronary Artery Disease With Myocardial Insulin Resistance: Patricia Iozzo, Panithaya Chareonthaitawee, David Dutka, D. John Betteridge, Ele Ferrannini, and Paolo G. Camici
Diabetes 2002 51: 3020 -3024. [Abstract] [Full Text] [PDF]

Effects of Insulin Treatment in Type 2 Diabetic Patients on Intracellular Lipid Content in Liver and Skeletal Muscle: Christian Anderwald, Elisabeth Bernroider, Martin Krssak, Harald Stingl, Attila Brehm, Martin G. Bischof, Peter Nowotny, Michael Roden, and Werner Waldhäusl
Diabetes 2002 51: 3025 -3032. [Abstract] [Full Text] [PDF]

Insulin Sensitively Controls the Glucagon Response to Mild Hypoglycemia in the Dog: Kayano Igawa, Mike Mugavero, Masakazu Shiota, Doss W. Neal, and Alan D. Cherrington
Diabetes 2002 51: 3033 -3042. [Abstract] [Full Text] [PDF]

Free Fatty Acids Reduce Splanchnic and Peripheral Glucose Uptake in Patients With Type 2 Diabetes: Mandeep Bajaj, Thongchai Pratipanawatr, Rachele Berria, Wilailak Pratipanawatr, Sangeeta Kashyap, Kenneth Cusi, Lawrence Mandarino, and Ralph A. DeFronzo
Diabetes 2002 51: 3043 -3048. [Abstract] [Full Text] [PDF]

Complications:

${alpha}$ -Tocopherol Decreases Superoxide Anion Release in Human Monocytes Under Hyperglycemic Conditions Via Inhibition of Protein Kinase C- ${alpha}$: Senthil Kumar Venugopal, Sridevi Devaraj, Teddy Yang, and Ishwarlal Jialal
Diabetes 2002 51: 3049 -3054. [Abstract] [Full Text] [PDF]

Naltrexone, an Opioid Antagonist, Facilitates Reepithelialization of the Cornea in Diabetic Rat: Ian S. Zagon, Joe B. Jenkins, Joseph W. Sassani, James D. Wylie, Torre B. Ruth, Jamie L. Fry, C. Max Lang, and Patricia J. McLaughlin
Diabetes 2002 51: 3055 -3062. [Abstract] [Full Text] [PDF]

Evidence for a Matrix Metalloproteinase Induction/Activation System in Arterial Vasculature and Decreased Synthesis and Activity in Diabetes: Vera Portik-Dobos, Mark P. Anstadt, Jimmie Hutchinson, Mary Bannan, and Adviye Ergul
Diabetes 2002 51: 3063 -3068. [Abstract] [Full Text] [PDF]

Risk Factor Groupings Related to Insulin Resistance and Their Synergistic Effects on Subclinical Atherosclerosis: The Atherosclerosis Risk in Communities Study: Sherita Hill Golden, Aaron R. Folsom, Josef Coresh, A. Richey Sharrett, Moyses Szklo, and Frederick Brancati
Diabetes 2002 51: 3069 -3076. [Abstract] [Full Text] [PDF]

C-Peptide Exerts Beneficial Effects on Myocardial Blood Flow and Function in Patients With Type 1 Diabetes: Alexander Hansen, Bo-Lennart Johansson, John Wahren, and Helene von Bibra
Diabetes 2002 51: 3077 -3082. [Abstract] [Full Text] [PDF]

Podocyte Number in Normotensive Type 1 Diabetic Patients With Albuminuria: Kathryn E. White, Rudolf W. Bilous, Sally M. Marshall, Meguid El Nahas, Giuseppe Remuzzi, Giampiero Piras, Salvatore De Cosmo, and GianCarlo Viberti
Diabetes 2002 51: 3083 -3089. [Abstract] [Full Text] [PDF]

Amelioration of Long-Term Renal Changes in Obese Type 2 Diabetic Mice by a Neutralizing Vascular Endothelial Growth Factor Antibody: Allan Flyvbjerg, Frederik Dagnæs-Hansen, An S. De Vriese, Bieke F. Schrijvers, Ronald G. Tilton, and Ruth Rasch
Diabetes 2002 51: 3090 -3094. [Abstract] [Full Text] [PDF]

Nitric Oxide Prevents Aldose Reductase Activation and Sorbitol Accumulation During Diabetes: Deepak Chandra, Elias B. Jackson, Kota V. Ramana, Rocky Kelley, Satish K. Srivastava, and Aruni Bhatnagar
Diabetes 2002 51: 3095 -3101. [Abstract] [Full Text] [PDF]

In Vivo Evidence for Increased Oxidation of Circulating LDL in Impaired Glucose Tolerance: Steffi Kopprasch, Jens Pietzsch, Eberhard Kuhlisch, Katja Fuecker, Theodora Temelkova-Kurktschiev, Markolf Hanefeld, Helmut Kühne, Ulrich Julius, and Jürgen Graessler
Diabetes 2002 51: 3102 -3106. [Abstract] [Full Text] [PDF]

Pericytes and the Pathogenesis of Diabetic Retinopathy: Hans-Peter Hammes, Jihong Lin, Oliver Renner, Moshe Shani, Andrea Lundqvist, Christer Betsholtz, Michael Brownlee, and Urban Deutsch
Diabetes 2002 51: 3107 -3112. [Abstract] [Full Text] [PDF]

Insulin Stimulates Long-Chain Fatty Acid Utilization by Rat Cardiac Myocytes Through Cellular Redistribution of FAT/CD36: Joost J.F.P. Luiken, Debby P.Y. Koonen, Jodil Willems, Antonio Zorzano, Christoph Becker, Yvan Fischer, Narendra N. Tandon, Ger J. van der Vusse, Arend Bonen, and Jan F.C. Glatz
Diabetes 2002 51: 3113 -3119. [Abstract] [Full Text] [PDF]

Epidemiology:

Components of the "Metabolic Syndrome" and Incidence of Type 2 Diabetes: Robert L. Hanson, Giuseppina Imperatore, Peter H. Bennett, and William C. Knowler
Diabetes 2002 51: 3120 -3127. [Abstract] [Full Text] [PDF]

Genetics:

A Polymorphism in the Glucocorticoid Receptor Gene, Which Decreases Sensitivity to Glucocorticoids In Vivo, Is Associated With Low Insulin and Cholesterol Levels: Elisabeth F.C. van Rossum, Jan W. Koper, Nannette A.T.M. Huizenga, André G. Uitterlinden, Joop A.M.J.L. Janssen, Albert O. Brinkmann, Diederick E. Grobbee, Frank H. de Jong, Cornelia M. van Duyn, Huibert A.P. Pols, and Steven W.J. Lamberts
Diabetes 2002 51: 3128 -3134. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

Variations in Insulin Secretion in Carriers of the E23K Variant in the KIR6.2 Subunit of the ATP-Sensitive K⁺ Channel in the ß-Cell: Leen M. ‘t Hart, Timon W. van Haeften, Jacqueline M. Dekker, Martine Bot, Robert J. Heine, and J. Antonie Maassen
Diabetes 2002 51: 3135 -3138. [Abstract] [Full Text] [PDF] Online Appendix