Diabetes -- Table of Contents (March 2002, 51 [3])

Rapid Publications:

Molecular Detection of Circulating ß-Cells After Islet Transplantation: Beate Ritz-Laser, José Oberholzer, Christian Toso, Marie-Claude Brulhart, Katerina Zakrzewska, Frédéric Ris, Pascal Bucher, Philippe Morel, and Jacques Philippe
Diabetes 2002 51: 557 -561. First published on February 4, 2002 as 10.2337/diabetes.51.3.557 [Abstract] [Full Text] [PDF]

Elevation of Cytotoxic Lymphocyte Gene Expression Is Predictive of Islet Allograft Rejection in Nonhuman Primates: Dongmei Han, Xiumin Xu, Ricardo L. Pastori, Camillo Ricordi, and Norma S. Kenyon
Diabetes 2002 51: 562 -566. First published on February 4, 2002 as 10.2337/diabetes.51.3.562 [Abstract] [Full Text] [PDF]

Metabolism and Signal Transduction:

Effect of AICAR Treatment on Glycogen Metabolism in Skeletal Muscle: William G. Aschenbach, Michael F. Hirshman, Nobuharu Fujii, Kei Sakamoto, Kirsten F. Howlett, and Laurie J. Goodyear
Diabetes 2002 51: 567 -573. [Abstract] [Full Text] [PDF]

Mode of Transcapillary Transport of Insulin and Insulin Analog NN304 in Dog Hindlimb: Evidence for Passive Diffusion: Marianthe Hamilton-Wessler, Marilyn Ader, Melvin K. Dea, Donna Moore, Mette Loftager, Jan Markussen, and Richard N. Bergman
Diabetes 2002 51: 574 -582. [Abstract] [Full Text] [PDF]

Caffeine-Induced Impairment of Insulin Action but Not Insulin Signaling in Human Skeletal Muscle Is Reduced by Exercise: Farah S.L. Thong, Wim Derave, Bente Kiens, Terry E. Graham, Birgitte Ursø, Jørgen F.P. Wojtaszewski, Bo F. Hansen, and Erik A. Richter
Diabetes 2002 51: 583 -590. [Abstract] [Full Text] [PDF]

Human Skeletal Muscle Expresses a Glycogen-Targeting Subunit of PP1 That Is Identical to the Insulin-Sensitive Glycogen-Targeting Subunit G_L of Liver: Shonagh Munro, Daniel J.R. Cuthbertson, Joan Cunningham, Mark Sales, and Patricia T.W. Cohen
Diabetes 2002 51: 591 -598. [Abstract] [Full Text] [PDF]

Mechanism of Amino Acid-Induced Skeletal Muscle Insulin Resistance in Humans: Michael Krebs, Martin Krssak, Elisabeth Bernroider, Christian Anderwald, Attila Brehm, Martin Meyerspeer, Peter Nowotny, Erich Roth, Werner Waldhäusl, and Michael Roden
Diabetes 2002 51: 599 -605. [Abstract] [Full Text] [PDF]

Fructose Improves the Ability of Hyperglycemia Per Se to Regulate Glucose Production in Type 2 Diabetes: Meredith Hawkins, Ilan Gabriely, Robert Wozniak, Cristian Vilcu, Harry Shamoon, and Luciano Rossetti
Diabetes 2002 51: 606 -614. [Abstract] [Full Text] [PDF]

Insulin and Isoproterenol Differentially Regulate Mitogen-Activated Protein Kinase-Dependent Na⁺-K⁺-2Cl^- Cotransporter Activity in Skeletal Muscle: Aidar R. Gosmanov and Donald B. Thomason
Diabetes 2002 51: 615 -623. [Abstract] [Full Text] [PDF]

Increased Fatty Acid Re-esterification by PEPCK Overexpression in Adipose Tissue Leads to Obesity Without Insulin Resistance: Sylvie Franckhauser, Sergio Muñoz, Anna Pujol, Alba Casellas, Efren Riu, Pedro Otaegui, Benli Su, and Fatima Bosch
Diabetes 2002 51: 624 -630. [Abstract] [Full Text] [PDF]

C₂-Ceramide Influences the Expression and Insulin-Mediated Regulation of Cyclic Nucleotide Phosphodiesterase 3B and Lipolysis in 3T3-L1 Adipocytes: Jie Mei, Lena Stenson Holst, Tova Rahn Landström, Cecilia Holm, David Brindley, Vincent Manganiello, and Eva Degerman
Diabetes 2002 51: 631 -637. [Abstract] [Full Text] [PDF]

Immunology and Transplantation:

Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice: Alex Rabinovitch, Wilma L. Suarez-Pinzon, A.M. James Shapiro, Ray V. Rajotte, and Robert Power
Diabetes 2002 51: 638 -645. [Abstract] [Full Text] [PDF]

Genetic Risk Determines the Emergence of Diabetes-Associated Autoantibodies in Young Children: Antti Kupila, Päivi Keskinen, Tuula Simell, Satu Erkkilä, Paula Arvilommi, Sari Korhonen, Teija Kimpimäki, Minna Sjöroos, Matti Ronkainen, Jorma Ilonen, Mikael Knip, and Olli Simell
Diabetes 2002 51: 646 -651. [Abstract] [Full Text] [PDF]

Islet Studies:

Dipeptidyl Peptidase IV-Resistant [D-Ala²]Glucose-Dependent Insulinotropic Polypeptide (GIP) Improves Glucose Tolerance in Normal and Obese Diabetic Rats: Simon A. Hinke, Richard W. Gelling, Raymond A. Pederson, Susanne Manhart, Cuilan Nian, Hans-Ulrich Demuth, and Christopher H.S. McIntosh
Diabetes 2002 51: 652 -661. [Abstract] [Full Text] [PDF]

Differential Effects of Hyperlipidemia on Insulin Secretion in Islets of Langerhans From Hyperglycemic Versus Normoglycemic Rats: Isabelle Briaud, Cynthia L. Kelpe, Lisa M. Johnson, Phuong Oanh T. Tran, and Vincent Poitout
Diabetes 2002 51: 662 -668. [Abstract] [Full Text] [PDF]

Assessment of the Role of Interstitial Glucagon in the Acute Glucose Secretory Responsiveness of In Situ Pancreatic ß-Cells: Karen Moens, Veerle Berger, Jung-Mo Ahn, Chris Van Schravendijk, Victor J. Hruby, Daniel Pipeleers, and Frans Schuit
Diabetes 2002 51: 669 -675. [Abstract] [Full Text] [PDF]

Peroxisomal Proliferator-Activated Receptor- ${gamma}$ Upregulates Glucokinase Gene Expression in ß-Cells: Ha-il Kim, Ji-Young Cha, So-Youn Kim, Jae-woo Kim, Kyung Jin Roh, Je-Kyung Seong, Nam Taek Lee, Kang-Yell Choi, Kyung-Sup Kim, and Yong-ho Ahn
Diabetes 2002 51: 676 -685. [Abstract] [Full Text] [PDF]

Gastrin Stimulates ß-Cell Neogenesis and Increases Islet Mass From Transdifferentiated but Not From Normal Exocrine Pancreas Tissue: Ilse Rooman, Jessy Lardon, and Luc Bouwens
Diabetes 2002 51: 686 -690. [Abstract] [Full Text] [PDF]

NFAT Regulates Insulin Gene Promoter Activity in Response to Synergistic Pathways Induced by Glucose and Glucagon-Like Peptide-1: Michael C. Lawrence, Harshika S. Bhatt, and Richard A. Easom
Diabetes 2002 51: 691 -698. [Abstract] [Full Text] [PDF]

Primary In Vivo Oscillations of Metabolism in the Pancreas: Peter Bergsten, Johanna Westerlund, Per Liss, and Per-Ola Carlsson
Diabetes 2002 51: 699 -703. [Abstract] [Full Text] [PDF]

Counteraction of Type 1 Diabetic Alterations by Engineering Skeletal Muscle to Produce Insulin: Insights From Transgenic Mice: Efren Riu, Alex Mas, Tura Ferre, Anna Pujol, Laurent Gros, Pedro Otaegui, Lluis Montoliu, and Fatima Bosch
Diabetes 2002 51: 704 -711. [Abstract] [Full Text] [PDF]

Unregulated Elevation of Glutamate Dehydrogenase Activity Induces Glutamine-Stimulated Insulin Secretion: Identification and Characterization of a GLUD1 Gene Mutation and Insulin Secretion Studies With MIN6 Cells Overexpressing the Mutant Glutamate Dehydrogenase: Yukio Tanizawa, Kazuaki Nakai, Terumasa Sasaki, Takatoshi Anno, Yasuharu Ohta, Hiroshi Inoue, Kiyosato Matsuo, Mayumi Koga, Susumu Furukawa, and Yoshitomo Oka
Diabetes 2002 51: 712 -717. [Abstract] [Full Text] [PDF]

Pathophysiology:

Regional Differences in the Response of Human Pre-Adipocytes to PPAR ${gamma}$ and RXR ${alpha}$ Agonists: Ciaran P. Sewter, Fiona Blows, Antonio Vidal-Puig, and Stephen O’Rahilly
Diabetes 2002 51: 718 -723. [Abstract] [Full Text] [PDF]

Hypoglycemia-Associated Autonomic Failure in Advanced Type 2 Diabetes: Scott A. Segel, Deanna S. Paramore, and Philip E. Cryer
Diabetes 2002 51: 724 -733. [Abstract] [Full Text] [PDF]

Systemic and Local Adrenergic Regulation of Muscle Glucose Utilization During Hypoglycemia in Healthy Subjects: Robert P. Hoffman, Christine A. Sinkey, John M. Dopp, and Bradley G. Phillips
Diabetes 2002 51: 734 -742. [Abstract] [Full Text] [PDF]

Increased Insulin Sensitivity in IGF-I Receptor–Deficient Brown Adipocytes: Cecilia Mur, Angela M. Valverde, C. Ronald Kahn, and Manuel Benito
Diabetes 2002 51: 743 -754. [Abstract] [Full Text] [PDF]

Extreme Insulin Resistance of the Central Adipose Depot In Vivo: Steven D. Mittelman, Gregg W. Van Citters, Erlinda L. Kirkman, and Richard N. Bergman
Diabetes 2002 51: 755 -761. [Abstract] [Full Text] [PDF]

Albumin Binding of Acylated Insulin (NN304) Does Not Deter Action to Stimulate Glucose Uptake: Melvin K. Dea, Marianthe Hamilton-Wessler, Marilyn Ader, Donna Moore, Lauge Schäffer, Mette Loftager, Aage Vølund, and Richard N. Bergman
Diabetes 2002 51: 762 -769. [Abstract] [Full Text] [PDF]

Unprocessed Proinsulin Promotes Cell Survival During Neurulation in the Chick Embryo: Catalina Hernández-Sánchez, Eva Rubio, José Serna, Enrique J. de la Rosa, and Flora de Pablo
Diabetes 2002 51: 770 -777. [Abstract] [Full Text] [PDF]

Attenuation of Diabetic Hyperphagia in Neuropeptide Y–Deficient Mice: Dana K. Sindelar, Paul Mystkowski, Donald J. Marsh, Richard D. Palmiter, and Michael W. Schwartz
Diabetes 2002 51: 778 -783. [Abstract] [Full Text] [PDF]

The Fate of [U-¹³C]Palmitate Extracted by Skeletal Muscle in Subjects With Type 2 Diabetes and Control Subjects: Ellen E. Blaak and Anton J.M. Wagenmakers
Diabetes 2002 51: 784 -789. [Abstract] [Full Text] [PDF]

Theophylline Improves Hypoglycemia Unawareness in Type 1 Diabetes: Bastiaan E. de Galan, Cees J. Tack, Jacques W. Lenders, Jaco W. Pasman, Lammy D. Elving, Frans G. Russel, Jos A. Lutterman, and Paul Smits
Diabetes 2002 51: 790 -796. [Abstract] [Full Text] [PDF]

The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes: Adam B. Mayerson, Ripudaman S. Hundal, Sylvie Dufour, Vincent Lebon, Douglas Befroy, Gary W. Cline, Staffan Enocksson, Silvio E. Inzucchi, Gerald I. Shulman, and Kitt F. Petersen
Diabetes 2002 51: 797 -802. [Abstract] [Full Text] [PDF]

Complications:

Association of Fasting Plasma Glucose With Heart Rate Recovery in Healthy Adults: A Population-Based Study: Claudia Panzer, Michael S. Lauer, Andreas Brieke, Eugene Blackstone, and Byron Hoogwerf
Diabetes 2002 51: 803 -807. [Abstract] [Full Text] [PDF]

Effects of Treatment With Sulfonylurea Drugs or Insulin on Ischemia-Induced Myocardial Dysfunction in Type 2 Diabetes: Roldano Scognamiglio, Angelo Avogaro, Saula Vigili de Kreutzenberg, Christian Negut, Monica Palisi, Eros Bagolin, and Antonio Tiengo
Diabetes 2002 51: 808 -812. [Abstract] [Full Text] [PDF]

Coronary Microvascular Adaptation to Myocardial Metabolic Demand Can Be Restored by Inhibition of Iron-Catalyzed Formation of Oxygen Free Radicals in Type 2 Diabetic Patients: Alain Nitenberg, Séverine Ledoux, Paul Valensi, Régis Sachs, and Isabelle Antony
Diabetes 2002 51: 813 -818. [Abstract] [Full Text] [PDF]

Morphometry of Dorsal Root Ganglion in Chronic Experimental Diabetic Neuropathy: Motoko Kishi, James Tanabe, James D. Schmelzer, and Phillip A. Low
Diabetes 2002 51: 819 -824. [Abstract] [Full Text] [PDF]

Genetics:

Deconstructing and Reconstructing Obesity-Induced Diabetes (Diabesity) in Mice: Peter C. Reifsnyder and Edward H. Leiter
Diabetes 2002 51: 825 -832. [Abstract] [Full Text] [PDF]

A Genome-Wide Scan for Loci Linked to Plasma Levels of Glucose and HbA_1c in a Community-Based Sample of Caucasian Pedigrees: The Framingham Offspring Study: James B. Meigs, Carolien I. M. Panhuysen, Richard H. Myers, Peter W.F. Wilson, and L. Adrienne Cupples
Diabetes 2002 51: 833 -840. [Abstract] [Full Text] [PDF] Additional Information

Factors of Insulin Resistance Syndrome–Related Phenotypes Are Linked to Genetic Locations on Chromosomes 6 and 7 in Nondiabetic Mexican-Americans: Rector Arya, John Blangero, Ken Williams, Laura Almasy, Thomas D. Dyer, Robin J. Leach, Peter O’Connell, Michael P. Stern, and Ravindranath Duggirala
Diabetes 2002 51: 841 -847. [Abstract] [Full Text] [PDF]

A Genomewide Linkage Scan for Abdominal Subcutaneous and Visceral Fat in Black and White Families: The HERITAGE Family Study: Treva Rice, Yvon C. Chagnon, Louis Pérusse, Ingrid B. Borecki, Olavi Ukkola, Tuomo Rankinen, Jacques Gagnon, Arthur S. Leon, James S. Skinner, Jack H. Wilmore, Claude Bouchard, and D.C. Rao
Diabetes 2002 51: 848 -855. [Abstract] [Full Text] [PDF]

Brief Genetics Reports:

A Genome-Wide Search for Linkage-Disequilibrium With Type 1 Diabetes in a Recent Genetically Isolated Population From the Netherlands: Norbert Vaessen, Peter Heutink, Jeanine J. Houwing-Duistermaat, Pieter J.L.M. Snijders, Tessa Rademaker, Leon Testers, Manou R. Batstra, Lodewijk A. Sandkuijl, Cornelia M. van Duijn, and Ben A. Oostra
Diabetes 2002 51: 856 -859. [Abstract] [Full Text] [PDF]

Human Resistin Gene, Obesity, and Type 2 Diabetes: Mutation Analysis and Population Study: Federica Sentinelli, Stefano Romeo, Marcello Arca, Emanuela Filippi, Frida Leonetti, Michela Banchieri, Umberto Di Mario, and Marco Giorgio Baroni
Diabetes 2002 51: 860 -862. [Abstract] [Full Text] [PDF]

Systematic Search for Single Nucleotide Polymorphisms in the Resistin Gene: The Absence of Evidence for the Association of Three Identified Single Nucleotide Polymorphisms With Japanese Type 2 Diabetes: Haruhiko Osawa, Hiroshi Onuma, Akiko Murakami, Masaaki Ochi, Tatsuya Nishimiya, Kenichi Kato, Ikki Shimizu, Yasuhisa Fujii, Jun Ohashi, and Hideichi Makino
Diabetes 2002 51: 863 -866. [Abstract] [Full Text] [PDF]

The Proline 12 Alanine Substitution in the Peroxisome Proliferator–Activated Receptor- ${gamma}$ 2 Gene Is Associated With Lower Lipoprotein Lipase Activity in Vivo: Jochen Schneider, Joerg Kreuzer, Andreas Hamann, Peter P. Nawroth, and Klaus A. Dugi
Diabetes 2002 51: 867 -870. [Abstract] [Full Text] [PDF]

Relationship Between TaqIB Cholesteryl Ester Transfer Protein Gene Polymorphism and Macrovascular Complications in Japanese Patients With Type 2 Diabetes: Isao Kawasaki, Hideki Tahara, Masanori Emoto, Tetsuo Shoji, and Yoshiki Nishizawa
Diabetes 2002 51: 871 -874. [Abstract] [Full Text] [PDF]

K_IR6.2 Polymorphism Predisposes to Type 2 Diabetes by Inducing Overactivity of Pancreatic ß-Cell ATP-Sensitive K⁺ Channels: Christina Schwanstecher, Ulrike Meyer, and Mathias Schwanstecher
Diabetes 2002 51: 875 -879. [Abstract] [Full Text] [PDF]

Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin Resistance: Evidence of Interaction With the Trp64Arg Variant of the ß-3-Adrenergic Receptor: Daniela Mentuccia, Laura Proietti-Pannunzi, Keith Tanner, Vincenzo Bacci, Toni I. Pollin, Eric T. Poehlman, Alan R. Shuldiner, and Francesco S. Celi
Diabetes 2002 51: 880 -883. [Abstract] [Full Text] [PDF] Online Tables

Variations in Insulin Secretion in Carriers of Gene Variants in IRS-1 and -2: Leen M. ’t Hart, Giel Nijpels, Jacqueline M. Dekker, J. Antonie Maassen, Robert J. Heine, and Timon W. van Haeften
Diabetes 2002 51: 884 -887. [Abstract] [Full Text] [PDF]

Letters to the Editor:

Status of Research Funded by the American Diabetes Association: Year 3: Mayer B. Davidson
Diabetes 2002 51: 888 . [Extract] [Full Text] [PDF]