Perspectives in Diabetes:

Glucose Allostasis

Michael Stumvoll, P. Antonio Tataranni, Norbert Stefan, Barbora Vozarova, and Clifton Bogardus
Diabetes 2003 52: 903 -909. [Abstract] [Full Text] [PDF]  

Metabolism and Signal Transduction:

Human Metabolic Syndrome Resulting From Dominant-Negative Mutations in the Nuclear Receptor Peroxisome Proliferator-Activated Receptor-

David B. Savage, Garry D. Tan, Carlo L. Acerini, Susan A. Jebb, Maura Agostini, Mark Gurnell, Rachel L. Williams, A. Margot Umpleby, E. Louise Thomas, Jimmy D. Bell, Adrian K. Dixon, Fidelma Dunne, Romina Boiani, Saverio Cinti, Antonio Vidal-Puig, Fredrik Karpe, V. Krishna K. Chatterjee, and Stephen O’Rahilly
Diabetes 2003 52: 910 -917. [Abstract] [Full Text] [PDF]  

Mechanisms for the Deterioration in Glucose Tolerance Associated With HIV Protease Inhibitor Regimens

Hans J. Woerle, Peter R. Mariuz, Christian Meyer, Richard C. Reichman, Emilia M. Popa, Jean M. Dostou, Stephen L. Welle, and John E. Gerich
Diabetes 2003 52: 918 -925. [Abstract] [Full Text] [PDF]  

Exercise Increases Nuclear AMPK ₂ in Human Skeletal Muscle

Sean L. McGee, Kirsten F. Howlett, Rebecca L. Starkie, David Cameron-Smith, Bruce E. Kemp, and Mark Hargreaves
Diabetes 2003 52: 926 -928. [Abstract] [Full Text] [PDF]  

Elevation in Tanis Expression Alters Glucose Metabolism and Insulin Sensitivity in H4IIE Cells

Yuan Gao, Ken Walder, Terry Sunderland, Lakshmi Kantham, Helen C. Feng, Melissa Quick, Natalie Bishara, Andrea de Silva, Guy Augert, Janette Tenne-Brown, and Gregory R. Collier
Diabetes 2003 52: 929 -934. [Abstract] [Full Text] [PDF]  

Defective Signaling Through Akt-2 and -3 But Not Akt-1 in Insulin-Resistant Human Skeletal Muscle: Potential Role in Insulin Resistance

Joseph T. Brozinick, Jr, Brian R. Roberts, and G. Lynis Dohm
Diabetes 2003 52: 935 -941. [Abstract] [Full Text] [PDF]  

Association Between Adiponectin and Mediators of Inflammation in Obese Women

Stefan Engeli, Mareike Feldpausch, Kerstin Gorzelniak, Frauke Hartwig, Ute Heintze, Jürgen Janke, Matthias Möhlig, Andreas F.H. Pfeiffer, Friedrich C. Luft, and Arya M. Sharma
Diabetes 2003 52: 942 -947. [Abstract] [Full Text] [PDF]  

Ghrelin Directly Interacts With Neuropeptide-Y-Containing Neurons in the Rat Arcuate Nucleus: Ca²⁺ Signaling via Protein Kinase A and N-Type Channel-Dependent Mechanisms and Cross-Talk With Leptin and Orexin

Daisuke Kohno, Hong-Zhi Gao, Shinji Muroya, Sakae Kikuyama, and Toshihiko Yada
Diabetes 2003 52: 948 -956. [Abstract] [Full Text] [PDF]  

Immunology and Transplantation:

Prolonged Islet Allograft Survival in Diabetic NOD Mice by Targeting CD45RB and CD154

R. Damaris Molano, Antonello Pileggi, Thierry Berney, Raffaella Poggioli, Elsie Zahr, Robert Oliver, Camillo Ricordi, David M. Rothstein, Giacomo P. Basadonna, and Luca Inverardi
Diabetes 2003 52: 957 -964. [Abstract] [Full Text] [PDF]  

Islet Studies:

Inhibition of Mitochondrial Na⁺-Ca²⁺ Exchanger Increases Mitochondrial Metabolism and Potentiates Glucose-Stimulated Insulin Secretion in Rat Pancreatic Islets

Bumsup Lee, Philip D. Miles, Leonardo Vargas, Peng Luan, Susan Glasco, Yulia Kushnareva, Elisabeth S. Kornbrust, Kathryn A. Grako, Claes B. Wollheim, Pierre Maechler, Jerrold M. Olefsky, and Christen M. Anderson
Diabetes 2003 52: 965 -973. [Abstract] [Full Text] [PDF]  

Differential Activation Mechanisms of Erk-1/2 and p70^S6K by Glucose in Pancreatic ß-Cells

Isabelle Briaud, Melissa K. Lingohr, Lorna M. Dickson, Christian E. Wrede, and Christopher J. Rhodes
Diabetes 2003 52: 974 -983. [Abstract] [Full Text] [PDF]  

Programming of Islet Functions in the Progeny of Hyperinsulinemic/Obese Rats

Malathi Srinivasan, Ravikumar Aalinkeel, Fei Song, and Mulchand S. Patel
Diabetes 2003 52: 984 -990. [Abstract] [Full Text] [PDF]  

Protein Kinase C Activation and Translocation to the Nucleus Are Required for Fatty Acid-Induced Apoptosis of Insulin-Secreting Cells

Katrin Eitel, Harald Staiger, Johannes Rieger, Harald Mischak, Heide Brandhorst, Mathias D. Brendel, Reinhard G. Bretzel, Hans-Ulrich Häring, and Monika Kellerer
Diabetes 2003 52: 991 -997. [Abstract] [Full Text] [PDF]  

Insulin Does Not Mediate Glucose Stimulation of Proinsulin Biosynthesis

Gil Leibowitz, Andrei I. Oprescu, Gökhan Üçkaya, David J. Gross, Erol Cerasi, and Nurit Kaiser
Diabetes 2003 52: 998 -1003. [Abstract] [Full Text] [PDF]  

Semicarbazide-Sensitive Amine Oxidase/Vascular Adhesion Protein-1 Activity Exerts an Antidiabetic Action in Goto-Kakizaki Rats

Anna Abella, Luc Marti, Marta Camps, Marc Claret, J. Fernández-Alvarez, Ramon Gomis, Anna Gumà, Nathalie Viguerie, Christian Carpéné, Manuel Palacín, Xavier Testar, and Antonio Zorzano
Diabetes 2003 52: 1004 -1013. [Abstract] [Full Text] [PDF]  

Complications:

Diabetes Can Alter the Signal Transduction Pathways in the Lens of Rats

D. Steven Zatechka, Jr, Peter F. Kador, Sixto Garcia-Castiñeiras, and Marjorie F. Lou
Diabetes 2003 52: 1014 -1022. [Abstract] [Full Text] [PDF]  

Nephrin Expression Is Reduced in Human Diabetic Nephropathy: Evidence for a Distinct Role for Glycated Albumin and Angiotensin II

Sophie Doublier, Gennaro Salvidio, Enrico Lupia, Vesa Ruotsalainen, Daniela Verzola, Giacomo Deferrari, and Giovanni Camussi
Diabetes 2003 52: 1023 -1030. [Abstract] [Full Text] [PDF]  

Is Podocyte Injury Relevant in Diabetic Nephropathy?: Studies in Patients With Type 2 Diabetes

Michele Dalla Vestra, Alessandra Masiero, Anna Maria Roiter, Alois Saller, Gaetano Crepaldi, and Paola Fioretto
Diabetes 2003 52: 1031 -1035. [Abstract] [Full Text] [PDF]  

Low Glomerular Filtration Rate in Normoalbuminuric Type 1 Diabetic Patients: An Indicator of More Advanced Glomerular Lesions

M. Luiza Caramori, Paola Fioretto, and Michael Mauer
Diabetes 2003 52: 1036 -1040. [Abstract] [Full Text] [PDF]  

Evaluation of Autofluorescent Property of Hemoglobin-Advanced Glycation End Product as a Long-Term Glycemic Index of Diabetes

Bijukumar Gopalkrishnapillai, Vigneshwaran Nadanathangam, Nivedita Karmakar, Sneh Anand, and Anoop Misra
Diabetes 2003 52: 1041 -1046. [Abstract] [Full Text] [PDF]  

Genetics:

Using Genetic Admixture to Explain Racial Differences in Insulin-Related Phenotypes

Barbara A. Gower, José R. Fernández, T. Mark Beasley, Mark D. Shriver, and Michael I. Goran
Diabetes 2003 52: 1047 -1051. [Abstract] [Full Text] [PDF]  

Brief Genetics Reports:

Genetic Liability of Type 1 Diabetes and the Onset Age Among 22,650 Young Finnish Twin Pairs: A Nationwide Follow-Up Study

Valma Hyttinen, Jaakko Kaprio, Leena Kinnunen, Markku Koskenvuo, and Jaakko Tuomilehto
Diabetes 2003 52: 1052 -1055. [Abstract] [Full Text] [PDF]  

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